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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal t... See more...
Aliases for CLDN11 Gene
Aliases for CLDN11 Gene
External Ids for CLDN11 Gene
- HGNC: 8514
- NCBI Entrez Gene: 5010
- Ensembl: ENSG00000013297
- OMIM®: 601326
- UniProtKB/Swiss-Prot: O75508
Previous HGNC Symbols for CLDN11 Gene
- OTM
Previous GeneCards Identifiers for CLDN11 Gene
- GC03P167279
- GC03P171185
- GC03P171538
- GC03P171457
- GC03P171619
- GC03P170136
- GC03P167506
Summaries for CLDN11 Gene
-
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Aug 2010]
GeneCards Summary for CLDN11 Gene
CLDN11 (Claudin 11) is a Protein Coding gene. Diseases associated with CLDN11 include Lyme Disease and Deafness, Autosomal Recessive 29. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration: Pathways Overview and Cell junction organization. Gene Ontology (GO) annotations related to this gene include identical protein binding and structural molecule activity. An important paralog of this gene is ENSG00000285218.
UniProtKB/Swiss-Prot Summary for CLDN11 Gene
-
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Additional gene information for CLDN11 Gene
- HGNC (8514)
- NCBI Entrez Gene (5010)
- Ensembl (ENSG00000013297)
- OMIM® (601326)
- UniProtKB/Swiss-Prot (O75508)
- Open Targets Platform(ENSG00000013297)
- Alliance of Genome Resources
- Search for CLDN11 at DataMed
- Search for CLDN11 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CLDN11 Gene
Genomics for CLDN11 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CLDN11 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CLDN11 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CLDN11
- Top Transcription factor binding sites by QIAGEN in the CLDN11 gene promoter:
-
- AML1a
- CREB
- deltaCREB
- Evi-1
- GATA-1
- GATA-2
- GATA-3
- USF-1
- USF1
Genomic Locations for CLDN11 Gene
Latest Assembly
- chr3:170,418,868-170,454,733
- (GRCh38/hg38)
- Size:
- 35,866 bases
- Orientation:
- Plus strand
Previous Assembly
- chr3:170,136,656-170,152,479
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 15,824 bases
- Orientation:
- Plus strand
Genomic View for CLDN11 Gene
Genes around CLDN11 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q26.2 by HGNC
- 3q26.2 by Entrez Gene
- 3q26.2 by Ensembl
CLDN11 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CLDN11 Gene
Proteins for CLDN11 Gene
-
Protein details for CLDN11 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75508-CLD11_HUMAN
- Recommended name:
- Claudin-11
- Protein Accession:
- O75508
- B2R7C1
- D3DNQ5
- Q5U0P3
Protein attributes for CLDN11 Gene
- Size:
- 207 amino acids
- Molecular mass:
- 21993 Da
- Quaternary structure:
-
- Interacts with tetraspanin-3/TSPAN3 (By similarity). Interacts with OCLN (PubMed:20375010).
Protein Expression for CLDN11 Gene
Post-translational modifications for CLDN11 Gene
Other Protein References for CLDN11 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences CLDN11 / Claudin 11 Antibody (LS-B939) and CLDN11 / Claudin 11 Antibody (LS-B13323)
-
Custom Antibody ServicesOriGene Antibodies for CLDN11
- Novus Biologicals Antibodies for CLDN11
-
Abcam antibodies for CLDN11
- Invitrogen Antibodies for CLDN11 (AFLGC-Cldn11)
- antibodies-online: Show 19 available CLDN11 Antibodies ranked by validation data
- Compare Top CLDN11 Antibodies
-
Recommended
- 52 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 10 FACS Antibodies (anti-human)
- 6 IHC (p) Antibodies (anti-human)
- 4 IHC Antibodies (anti-human)
- 34 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 4 IHC (p) Antibodies (anti-mouse)
- 3 IHC Antibodies (anti-mouse)
- 36 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
-
Biorbyt antibodies for CLDN11
-
Boster Bio Antibodies for CLDN11
-
Custom Antibody ServicesProSci Antibodies for CLDN11
-
Santa Cruz Biotechnology (SCBT) Antibodies for CLDN11
Protein products for research
-
OriGene Purified Proteins for CLDN11
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- Sino Biological Recombinant Proteins for CLDN11
- Sino Biological Cell Lysates for CLDN11
-
Abcam proteins for CLDN11
Assay products for research
- G Biosciences Immunotag™ Human CLDN11 (Claudin 11) ELISA
- Novus Biologicals ELISA Kits for CLDN11
-
Boster Bio ELISA Kits for CLDN11
No data available for DME Specific Peptides for CLDN11 Gene
Domains & Families for CLDN11 Gene
Gene Families for CLDN11 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for CLDN11 Gene
- InterPro:
- Blocks:
-
- Claudin family signature
- Claudin-11 signature
Suggested Antigen Peptide Sequences for CLDN11 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ57917, highly similar to Claudin-11 (B4DFI2_HUMAN)
- Oligodendrocyte-specific protein (CLD11_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O75508- Family:
-
- Belongs to the claudin family.
Function for CLDN11 Gene
Molecular function for CLDN11 Gene
- UniProtKB/Swiss-Prot Function:
- Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Phenotypes From GWAS Catalog for CLDN11 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005198 | structural molecule activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 20375010 |
| GO:0042802 | identical protein binding | IMP,ISS | -- |
Phenotypes for CLDN11 Gene
- MGI mutant phenotypes for CLDN11:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for CLDN11:
Animal Models for CLDN11 Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for CLDN11 - Starting at $85 >
- * CLDN11 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
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- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CLDN11
-
Santa Cruz Biotechnology (SCBT) CRISPR for CLDN11
miRNA for CLDN11 Gene
- miRTarBase miRNAs that target CLDN11
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CLDN11
- Browse OriGene Inhibitory RNA Products For CLDN11
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Clone products for research
- Applied Biological Materials (abm): Clones for CLDN11 - Starting at $45 >
- * CLDN11 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for CLDN11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CLDN11
Cell Lines for research
-
Horizon Cell Lines for CLDN11
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CLDN11 Gene
Localization for CLDN11 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CLDN11 Gene
- Cell junction, tight junction. Cell membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytoskeleton | 4 |
| extracellular | 2 |
| nucleus | 2 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| cytosol | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Cell Junctions (3)
- Lipid droplets (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005811 | lipid droplet | IDA | -- |
| GO:0005883 | neurofilament | IDA | 30734065 |
| GO:0005886 | plasma membrane | IBA,IDA | 20375010 |
| GO:0005923 | bicellular tight junction | IBA,ISS | -- |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for CLDN11 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling Pathways | ||
| 2 | Cell junction organization | ||
| 3 | Blood-Brain Barrier and Immune Cell Transmigration: Pathways Overview | ||
| 4 | Sertoli-Sertoli Cell Junction Dynamics |
Sertoli-Sertoli Cell Junction Dynamics
.38
|
Epithelial Tight Junctions
.36
|
| 5 | Cell adhesion molecules | ||
Pathways by source for CLDN11 Gene
1 BioSystems pathway for CLDN11 Gene
4 Reactome pathways for CLDN11 Gene
5 KEGG pathways for CLDN11 Gene
1 GeneGo (Thomson Reuters) pathway for CLDN11 Gene
- Cell adhesion Tight junctions
6 R&D Systems pathways for CLDN11 Gene
- Blood-Brain Barrier and Immune Cell Transmigration: CCL2/MCP-1 Signaling Pathways
- Blood-Brain Barrier and Immune Cell Transmigration: ICAM-1/CD54 Signaling Pathways
- Blood-Brain Barrier and Immune Cell Transmigration: Pathways Overview
- Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling Pathways
- Blood-Brain Barrier and Immune Cell Transmigration: VEGF Signaling Pathways
3 Qiagen pathways for CLDN11 Gene
- Epithelial Tight Junctions
- Sertoli-Sertoli Cell Junction Dynamics
- Transendothelial Migration of Leukocytes
Interacting Proteins for CLDN11 Gene
Selected Interacting proteins:
O75508-CLD11_HUMAN
ENSP00000064724
for CLDN11 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for CLDN11
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007155 | cell adhesion | IEA,IBA | 21873635 |
| GO:0007283 | spermatogenesis | IEA | -- |
| GO:0008366 | axon ensheathment | IEA | -- |
| GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules | ISS | -- |
| GO:0070830 | bicellular tight junction assembly | IBA | 21873635 |
No data available for SIGNOR curated interactions for CLDN11 Gene
Drugs & Compounds for CLDN11 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Calcium | Nutra | 6959 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for CLDN11 Gene
mRNA/cDNA for CLDN11 Gene
- 2 REFSEQ mRNAs :
- 11 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000064724 2758 nts (view in UCSC)
- ENST00000468358 593 nts (view in UCSC)
- ENST00000477531 1065 nts (view in UCSC)
- ENST00000486429 998 nts (view in UCSC)
- ENST00000488989 600 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for CLDN11 - Starting at $85 >
- * CLDN11 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for CLDN11
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CLDN11
-
Santa Cruz Biotechnology (SCBT) CRISPR for CLDN11
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CLDN11
- Browse OriGene Inhibitory RNA Products For CLDN11
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CLDN11
Clone products for research
- Applied Biological Materials (abm): Clones for CLDN11 - Starting at $45 >
- * CLDN11 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for CLDN11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CLDN11
Relevant External Links for CLDN11 Gene
- GeneLoc Exon Structure for
- CLDN11
Expression for CLDN11 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Kidney (Urinary System)
- Ureteric Bud Cells Ureteric Bud
- Loop of Henle Cells Loop of Henle
- Proximal Tubule Cells Proximal Tubule
-
Epithelial Cells
- Loop of Henle Cells Loop of Henle
- Mature Choroid Plexus Cells Choroid Plexus
- Proximal Tubule Cells Proximal Tubule
-
Spinal Cord (Nervous System)
- Myelinating Oligodendrocyte Cells Spinal Cord White Matter
- Oligodendrocyte-like cells(Najm FJ et. al. 2011)
-
Glial Cells
- Myelinating Oligodendrocyte Cells Spinal Cord White Matter
- Oligodendrocyte-like cells(Najm FJ et. al. 2011)
- Bone (Muscoskeletal System)
- Endothelium (Cardiovascular System)
-
Heart (Cardiovascular System)
- Atrioventricular Node Cells Atrioventricular Node
-
Eye (Sensory Organs)
- nGnG Amacrine Cells Inner Nuclear Layer
-
Neurons
- nGnG Amacrine Cells Inner Nuclear Layer
-
Peripheral Nervous System (Nervous System)
- Immature Schwann Cells Peripheral Nerve Domain
-
Head Mesenchyme (Muscoskeletal System)
- Dental Mesenchymal Cells Branchial Arch 1
-
Tooth
- Dental Mesenchymal Cells Branchial Arch 1
- Lung (Respiratory System)
- Limb (Muscoskeletal System)
- Dermis (Integumentary System)
- Fibroblasts
- Adipose (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
- Skeletal Muscle (Muscoskeletal System)
-
Testis (Reproductive System)
-
Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for CLDN11 Gene
This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x10.2) and Brain - Substantia nigra (x5.2).
This gene is overexpressed in Frontal cortex (38.2) and Spinal cord (23.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CLDN11 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CLDN11
SOURCE GeneReport for Unigene cluster for CLDN11 Gene:
Hs.31595Evidence on tissue expression from TISSUES for CLDN11 Gene
- Nervous system(4.9)
- Lung(4.3)
- Skin(2.1)
- Intestine(2)
Primer products for research
-
OriGene qPCR primer pairs for CLDN11
-
OriGene qPCR primer pairs and template standards for CLDN11
Gene Expression Assays for research
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CLDN11 Gene
Orthologs for CLDN11 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | CLDN11 29 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | CLDN11 29 30 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | CLDN11 29 30 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | CLDN11 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Cldn11 29 |
|
||
| Mouse (Mus musculus) |
Mammalia | Cldn11 29 16 30 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | CLDN11 29 30 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | CLDN11 30 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | cldn11 29 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | cldn11a 29 30 |
|
OneToMany | |
| cldn11b 30 |
|
OneToMany | |||
| Dr.12486 29 |
|
- Species where no ortholog for CLDN11 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for CLDN11 Gene
- ENSEMBL:
- Gene Tree for CLDN11 (if available)
- TreeFam:
- Gene Tree for CLDN11 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CLDN11: view image
- Alliance of Genome Resources:
- Additional Orthologs for CLDN11
Paralogs for CLDN11 Gene
Paralogs for CLDN11 Gene
(7) SIMAP similar genes for CLDN11 Gene using alignment to 2 proteins:
- CLD11_HUMAN
- B4DFI2_HUMAN
Variants for CLDN11 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CLDN11 Gene
| SNP ID | Clinical significance and condition | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1577466242 | Uncertain Significance: Marfanoid habitus and intellectual disability | 170,419,158(+) |
TGGTGACCTGCGG/T NM_005602.6(CLDN11):c.93_104del (p.Val32_Gly35del) |
INFRAME_DELETION |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
38.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.27;
6.12% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CLDN11 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CLDN11 Gene
Disorders for CLDN11 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| lyme disease |
|
|
| deafness, autosomal recessive 29 |
|
|
| pyriform sinus cancer |
|
|
| microcystic adenoma |
|
|
| orchitis |
|
|
Search CLDN11 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CLDN11
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for CLDN11 Gene
Publications for CLDN11 Gene
- Involvement of OSP/claudin-11 in oligodendrocyte membrane interactions: role in biology and disease. (PMID: 10700007) Bronstein JM … Stevens DB (Journal of neuroscience research 2000) 3 4 22
- Isolation and characterization of a novel oligodendrocyte-specific protein. (PMID: 8797478) Bronstein JM … Farber DB (Neurology 1996) 2 3 22
- Chromosomal localization of murine and human oligodendrocyte-specific protein genes. (PMID: 8661061) Bronstein JM … Farber DB (Genomics 1996) 2 3 22
- Claudin association with CD81 defines hepatitis C virus entry. (PMID: 20375010) Harris HJ … McKeating JA (The Journal of biological chemistry 2010) 3 4
- Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells. (PMID: 19956721) Agarwal R … Meltzer SJ (PloS one 2009) 3 22
ExternalLinks
Products for CLDN11 Gene
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- antibodies-online: Show 19 available CLDN11 Antibodies ranked by validation data
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- 4 IHC Antibodies (anti-human)
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- 12 IF (p) Antibodies (anti-rat)
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- antibodies-online: Show 33 available CLDN11 Elisa Kits ranked by validation data
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- antibodies-online: Show 6 available CLDN11 Proteins ranked by validation data
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- Santa Cruz Biotechnology (SCBT) Antibodies for CLDN11
- Search Santa Cruz Biotechnology (SCBT) for CLDN11 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CLDN11
- Custom Antibody ServicesProSci Antibodies for CLDN11
- Search for CLDN11 Proteins at ProSci
- Horizon Cell Lines for CLDN11
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CLDN11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CLDN11
- Search GeneCopoeia for miRNA 3'UTR Target clone products for CLDN11
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CLDN11
- Boster Bio Antibodies for CLDN11
- Boster Bio ELISA Kits for CLDN11
- Biorbyt antibodies for CLDN11
Sources for CLDN11 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources