Aliases for CIAO1 Gene
External Ids for CIAO1 Gene
Previous HGNC Symbols for CIAO1 Gene
Previous GeneCards Identifiers for CIAO1 Gene
GeneCards Summary for CIAO1 Gene
CIAO1 (Cytosolic Iron-Sulfur Assembly Component 1) is a Protein Coding gene. Diseases associated with CIAO1 include Hereditary Paraganglioma-Pheochromocytoma Syndromes and Retinitis Pigmentosa. Among its related pathways are Metabolism and Glucose / Energy Metabolism. An important paralog of this gene is WSB2.
UniProtKB/Swiss-Prot for CIAO1 Gene
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.