CHST3 Gene (Protein Coding)

Carbohydrate Sulfotransferase 3

GC10P071964
GIFtS:
42
This gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis. [provided by RefSeq, Mar 2009] See more...

Aliases for CHST3 Gene

Aliases for CHST3 Gene

  • Carbohydrate Sulfotransferase 3 2 3 4 5
  • Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 0 3 4
  • Carbohydrate (Chondroitin 6) Sulfotransferase 3 2 3
  • Chondroitin 6-O-Sulfotransferase 1 3 4
  • Chondroitin 6 Sulfotransferase 1 2 3
  • EC 2.8.2.17 4 51
  • C6ST-1 3 4
  • C6ST1 2 3
  • GST-0 3 4
  • C6ST 2 3
  • Chondroitin 6-Sulfotransferase 4
  • EC 2.8.2 51
  • CHST3 5
  • HSD 3

External Ids for CHST3 Gene

Previous GeneCards Identifiers for CHST3 Gene

  • GC10P072502
  • GC10P072827
  • GC10P073616
  • GC10P073068
  • GC10P073394
  • GC10P073724
  • GC10P067718

Summaries for CHST3 Gene

Entrez Gene Summary for CHST3 Gene

  • This gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis. [provided by RefSeq, Mar 2009]

GeneCards Summary for CHST3 Gene

CHST3 (Carbohydrate Sulfotransferase 3) is a Protein Coding gene. Diseases associated with CHST3 include Spondyloepiphyseal Dysplasia With Congenital Joint Dislocations and Larsen Syndrome. Among its related pathways are Glycosaminoglycan metabolism and Chondroitin sulfate/dermatan sulfate metabolism. Gene Ontology (GO) annotations related to this gene include sulfotransferase activity and chondroitin 6-sulfotransferase activity. An important paralog of this gene is CHST1.

UniProtKB/Swiss-Prot Summary for CHST3 Gene

  • Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen.

Additional gene information for CHST3 Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CHST3 Gene

Genomics for CHST3 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for CHST3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CHST3 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CHST3

Top Transcription factor binding sites by QIAGEN in the CHST3 gene promoter:
  • E2F
  • E2F-1
  • E2F-2
  • HNF-3beta
  • HNF-4alpha1
  • HNF-4alpha2
  • RelA
  • SEF-1 (1)
  • Sox9
  • STAT3

Genomic Locations for CHST3 Gene

Genomic Locations for CHST3 Gene
chr10:71,964,395-72,013,562
(GRCh38/hg38)
Size:
49,168 bases
Orientation:
Plus strand
chr10:73,724,120-73,773,322
(GRCh37/hg19)
Size:
49,203 bases
Orientation:
Plus strand

Genomic View for CHST3 Gene

Genes around CHST3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CHST3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CHST3 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for CHST3 Gene

Proteins for CHST3 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for CHST3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7LGC8-CHST3_HUMAN
    Recommended name:
    Carbohydrate sulfotransferase 3
    Protein Accession:
    Q7LGC8
    Secondary Accessions:
    • O75099
    • Q52M30

    Protein attributes for CHST3 Gene

    Size:
    479 amino acids
    Molecular mass:
    54706 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CHST3 Gene

Protein Expression for CHST3 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Selected DME Specific Peptides for CHST3 Gene

Q7LGC8:
  • EVQRLRGNCE
  • YMLVRYED
  • LLMATTRTGSSFVGEFFNQ
  • SSEQFEKWR
  • GSALVYRDVL
  • LVRDPRAV
  • IFYLFEPLWH

Post-translational modifications for CHST3 Gene

  • Glycosylation at Asn63, Asn74, Asn96, Asn256, Asn420, and Asn464
  • Modification sites at PhosphoSitePlus

Other Protein References for CHST3 Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains & Families for CHST3 Gene

Gene Families for CHST3 Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted membrane proteins

Protein Domains for CHST3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CHST3 Gene

GenScript: Design optimal peptide antigens:
  • Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0 (CHST3_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q7LGC8

UniProtKB/Swiss-Prot:

CHST3_HUMAN :
  • Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
Family:
  • Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
genes like me logo Genes that share domains with CHST3: view

Function for CHST3 Gene

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  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Molecular function for CHST3 Gene

UniProtKB/Swiss-Prot Function:
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=n 3'-phosphoadenylyl sulfate + chondroitin beta-D-glucuronate = n adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate + 2 H(+); Xref=Rhea:RHEA:11108, Rhea:RHEA-COMP:9827, Rhea:RHEA-COMP:9828, ChEBI:CHEBI:15378, ChEBI:CHEBI:57652, ChEBI:CHEBI:58339, ChEBI:CHEBI:58343, ChEBI:CHEBI:62065; EC=2.8.2.17;.

Enzyme Numbers (IUBMB) for CHST3 Gene

Phenotypes From GWAS Catalog for CHST3 Gene

Gene Ontology (GO) - Molecular Function for CHST3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity IBA 21873635
GO:0008146 sulfotransferase activity TAS 9883891
GO:0008459 chondroitin 6-sulfotransferase activity IBA,IDA 9883891
GO:0016740 transferase activity IEA --
genes like me logo Genes that share ontologies with CHST3: view
genes like me logo Genes that share phenotypes with CHST3: view

Human Phenotype Ontology for CHST3 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for CHST3 Gene

MGI Knock Outs for CHST3:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CHST3

No data available for Transcription Factor Targets and HOMER Transcription for CHST3 Gene

Localization for CHST3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CHST3 Gene

Golgi apparatus membrane. Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CHST3 gene
Compartment Confidence
golgi apparatus 5
cytosol 3
plasma membrane 2
extracellular 2
cytoskeleton 2
mitochondrion 2
nucleus 2
endoplasmic reticulum 1
endosome 1
lysosome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Golgi apparatus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CHST3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane TAS --
GO:0005794 Golgi apparatus IEA --
GO:0005802 trans-Golgi network IBA 21873635
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CHST3: view

Pathways & Interactions for CHST3 Gene

genes like me logo Genes that share pathways with CHST3: view

Gene Ontology (GO) - Biological Process for CHST3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005975 carbohydrate metabolic process IEA --
GO:0006044 N-acetylglucosamine metabolic process IBA 21873635
GO:0006790 sulfur compound metabolic process IBA,IDA 9883891
GO:0030206 chondroitin sulfate biosynthetic process IBA,TAS --
genes like me logo Genes that share ontologies with CHST3: view

No data available for SIGNOR curated interactions for CHST3 Gene

Drugs & Compounds for CHST3 Gene

Products:

  1. Drug

(9) Drugs for CHST3 Gene - From: PharmGKB, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Docetaxel Approved, Investigational Pharma Microtubulin disassembly inhibitor, Tubulin and VEGF inhibitor, Taxanes 2330
Thalidomide Approved, Investigational, Withdrawn Pharma Immunomodulatory agent,sedative drug,angiogenesis inhibitor, TNF-alpha synthesis inhibitor, Immunomodulatory agents 429
3'-phospho-5'-adenylyl sulfate Experimental Pharma 0
Adenosine 3',5'-diphosphate Experimental Pharma 0
Chondroitin Pharma 74

(7) Additional Compounds for CHST3 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Chondroitin 6'-sulfate
Keratan
  • Keratan 6'-sulfate
  • Keratan 6'-sulphate
  • Keratan sulfate
  • Keratan sulphate
  • kerato 6'-Sulfate
 69992-87-6
n-acetyllactosamine
  • beta-D-Galactosyl-1,4-N-acetyl-D-glucosamine
  • Galb1-4glcnacb
  • Galbeta1-4glcnacbeta
  • LacNAc
  • b-D-Galactosyl-1,4-N-acetyl-D-glucosamine
 32181-59-2
genes like me logo Genes that share compounds with CHST3: view

Transcripts for CHST3 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for CHST3 Gene

1 REFSEQ mRNAs :
10 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CHST3

Alternative Splicing Database (ASD) splice patterns (SP) for CHST3 Gene

No ASD Table

Relevant External Links for CHST3 Gene

GeneLoc Exon Structure for
CHST3

Expression for CHST3 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CHST3 Gene

mRNA expression in normal human tissues for CHST3 Gene
mRNA expression by BioGPS for CHST3 GenemRNA expression by GTEx for CHST3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CHST3 Gene

This gene is overexpressed in Monocytes (25.9), Colon muscle (17.2), Testis (14.5), and Platelet (11.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CHST3 Gene



Protein tissue co-expression partners for CHST3 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CHST3

SOURCE GeneReport for Unigene cluster for CHST3 Gene:

Hs.158304

mRNA Expression by UniProt/SwissProt for CHST3 Gene:

Q7LGC8-CHST3_HUMAN
Tissue specificity: Widely expressed in adult tissues. Expressed in heart, placenta, skeletal muscle and pancreas. Also expressed in various immune tissues such as spleen, lymph node, thymus and appendix.

Evidence on tissue expression from TISSUES for CHST3 Gene

  • Nervous system(4.6)
  • Liver(4.6)
  • Heart(2.2)
  • Kidney(2.1)
  • Skin(2.1)
  • Muscle(2.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for CHST3 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • integumentary
  • nervous
  • respiratory
  • skeletal muscle
  • skeleton
Regions:
Head and neck:
  • brain
  • cerebellum
  • ear
  • eye
  • head
  • jaw
  • mandible
  • maxilla
  • mouth
  • neck
  • outer ear
  • skull
  • tooth
Thorax:
  • aorta
  • breast
  • chest wall
  • clavicle
  • heart
  • heart valve
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
Pelvis:
  • pelvis
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • blood
  • blood vessel
  • peripheral nerve
  • peripheral nervous system
  • skin
  • spinal column
  • vertebrae
genes like me logo Genes that share expression patterns with CHST3: view

No data available for mRNA differential expression in normal tissues for CHST3 Gene

Orthologs for CHST3 Gene

This gene was present in the common ancestor of animals.

Orthologs for CHST3 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia CHST3 30 31
  • 99.79 (n)
 OneToOne
Dog
(Canis familiaris)
 Mammalia CHST3 30 31
  • 90.08 (n)
 OneToOne
Cow
(Bos Taurus)
 Mammalia CHST3 30 31
  • 87.11 (n)
 OneToOne
Rat
(Rattus norvegicus)
 Mammalia Chst3 30
  • 86.08 (n)
Oppossum
(Monodelphis domestica)
 Mammalia CHST3 31
  • 86 (a)
 OneToOne
Mouse
(Mus musculus)
 Mammalia Chst3 30 17 31
  • 85.17 (n)
 OneToOne
Chicken
(Gallus gallus)
 Aves CHST3 30 31
  • 80.27 (n)
 OneToOne
Lizard
(Anolis carolinensis)
 Reptilia CHST3 31
  • 81 (a)
 OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
 Amphibia chst3 30
  • 65.65 (n)
Zebrafish
(Danio rerio)
 Actinopterygii chst3b 30 31
  • 69.66 (n)
 OneToMany
chst3a 31
  • 58 (a)
 OneToMany
Fruit Fly
(Drosophila melanogaster)
 Insecta CG9550 31
  • 20 (a)
 ManyToMany
CG31637 31
  • 18 (a)
 ManyToMany
Sea Squirt
(Ciona savignyi)
 Ascidiacea -- 31
  • 35 (a)
 ManyToMany
-- 31
  • 29 (a)
 ManyToMany
-- 31
  • 28 (a)
 ManyToMany
-- 31
  • 23 (a)
 ManyToMany
-- 31
  • 22 (a)
 ManyToMany
-- 31
  • 22 (a)
 ManyToMany
CSA.5535 31
  • 21 (a)
 ManyToMany
-- 31
  • 20 (a)
 ManyToMany
Species where no ortholog for CHST3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for CHST3 Gene

ENSEMBL:
Gene Tree for CHST3 (if available)
TreeFam:
Gene Tree for CHST3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CHST3: view image

Paralogs for CHST3 Gene

Paralogs for CHST3 Gene

(4) SIMAP similar genes for CHST3 Gene using alignment to 1 proteins:

  • CHST3_HUMAN
genes like me logo Genes that share paralogs with CHST3: view

Variants for CHST3 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CHST3 Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
6045 Pathogenic: Spondyloepiphyseal dysplasia with congenital joint dislocations 72,008,116(+) TG/T FRAMESHIFT_VARIANT
694680 Pathogenic: Larsen syndrome, dominant type 72,008,283(+) CAGA/C INFRAME_DELETION
715153 Conflicting Interpretations: Spondyloepiphyseal dysplasia with congenital joint dislocations 72,008,166(+) C/T SYNONYMOUS_VARIANT
737568 Likely Benign: not provided 72,008,216(+) G/A SYNONYMOUS_VARIANT
742648 Conflicting Interpretations: Spondyloepiphyseal dysplasia with congenital joint dislocations; not provided 72,007,454(+) G/A SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for CHST3 Gene

Structural Variations from Database of Genomic Variants (DGV) for CHST3 Gene

Variant ID Type Subtype PubMed ID
dgv1263n54 CNV loss 21841781
esv3623787 CNV loss 21293372
nsv1122538 CNV deletion 24896259
nsv551509 CNV loss 21841781
nsv551512 CNV loss 21841781
nsv7110 CNV insertion 18451855
nsv820285 CNV loss 19587683

Variation tolerance for CHST3 Gene

Residual Variation Intolerance Score: 31.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.06; 84.35% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CHST3 Gene

Human Gene Mutation Database (HGMD)
CHST3
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CHST3

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CHST3 Gene

Disorders for CHST3 Gene

MalaCards: The human disease database

(14) MalaCards diseases for CHST3 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search CHST3 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

CHST3_HUMAN
  • Spondyloepiphyseal dysplasia with congenital joint dislocations (SEDCJD) [MIM:143095]: A bone dysplasia clinically characterized by dislocation of the knees and/or hips at birth, clubfoot, elbow joint dysplasia with subluxation and limited extension, short stature, and progressive kyphosis developing in late childhood. The disorder is usually evident at birth, with short stature and multiple joint dislocations or subluxations that dominate the neonatal clinical and radiographic picture. During childhood, the dislocations improve, both spontaneously and with surgical treatment, and features of spondyloepiphyseal dysplasia become apparent, leading to arthritis of the hips and spine with intervertebral disk degeneration, rigid kyphoscoliosis, and trunk shortening by late childhood. {ECO:0000269 PubMed:15215498, ECO:0000269 PubMed:18513679}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for CHST3

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with CHST3: view

No data available for Genatlas for CHST3 Gene

Publications for CHST3 Gene

  1. Molecular cloning and expression of human chondroitin 6-sulfotransferase. (PMID: 9714738) Fukuta M … Habuchi O (Biochimica et biophysica acta 1998) 2 3 4 23
  2. Functional expression and genomic structure of human chondroitin 6-sulfotransferase. (PMID: 9883891) Tsutsumi K … Sugahara K (FEBS letters 1998) 2 3 4 23
  3. Congenital joint dislocations caused by carbohydrate sulfotransferase 3 deficiency in recessive Larsen syndrome and humero-spinal dysostosis. (PMID: 18513679) Hermanns P … Superti-Furga A (American journal of human genetics 2008) 3 4 23
  4. Loss of chondroitin 6-O-sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement. (PMID: 15215498) Thiele H … Mundlos S (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 23
  5. Omani-type spondyloepiphyseal dysplasia with cardiac involvement caused by a missense mutation in CHST3. (PMID: 19320654) Tuysuz B … Turkmen S (Clinical genetics 2009) 3 23

ExternalLinks

View latest publications for CHST3 gene in Mastermind

Products for CHST3 Gene

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