Aliases for CHPF Gene
External Ids for CHPF Gene
Previous GeneCards Identifiers for CHPF Gene
GeneCards Summary for CHPF Gene
CHPF (Chondroitin Polymerizing Factor) is a Protein Coding gene. Diseases associated with CHPF include Breast Pericanalicular Fibroadenoma and Coffin-Siris Syndrome 1. Among its related pathways are Glycosaminoglycan metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring glycosyl groups and glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. An important paralog of this gene is CHPF2.
UniProtKB/Swiss-Prot Summary for CHPF Gene
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PRKN transport into the mitochondria. In collaboration with PRKN, isoform 2 may enhance cell viability and protect cells from oxidative stress.