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CHMP7 (Charged Multivesicular Body Protein 7) is a Protein Coding gene. Diseases associated with CHMP7 include Cerebellar Ataxia Type 48 and Attention Deficit-Hyperactivity Disorder. Among its related pathways are Budding and maturation of HIV virion and Necroptosis. Gene Ontology (GO) annotations related to this gene include protein transporter activity. An important paralog of this gene is CHMP5.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 16856878 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000785 | colocalizes_with chromatin | IDA | 28242692 |
GO:0000815 | ESCRT III complex | NAS | 28242692 |
GO:0005623 | cell | IEA | -- |
GO:0005634 | nucleus | IEA | -- |
GO:0005635 | nuclear envelope | IEA,IDA | 26040712 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | HIV Life Cycle |
.91
.65
|
.45
|
2 | Budding and maturation of HIV virion | ||
3 | Vesicle-mediated transport | ||
4 | Endocytosis | ||
5 | Necroptosis |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006900 | vesicle budding from membrane | IBA | 21873635 |
GO:0006997 | nucleus organization | IMP | 20616062 |
GO:0007034 | vacuolar transport | IEA | -- |
GO:0007080 | mitotic metaphase plate congression | IMP | 20616062 |
GO:0010458 | exit from mitosis | IMP | 26040712 |
ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
SP3: | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
SP6: | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP7: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP8: | |||||||||||||||||||||||||||||||||||||||||||||||
SP9: | - |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | CHMP7 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | CHMP7 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | CHMP7 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | CHMP7 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Chmp7 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Chmp7 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | CHMP7 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | CHMP7 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | CHMP7 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | chmp7 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | chmp7 30 31 |
|
OneToOne | |
zgc73300 30 |
|
||||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP012459 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG5498 30 31 |
|
OneToOne | |
Worm (Caenorhabditis elegans) |
Secernentea | T24B8.2 30 31 |
|
OneToOne |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2736756 | CNV | deletion | 23290073 |
esv2759604 | CNV | loss | 17122850 |
nsv1017570 | CNV | gain | 25217958 |
nsv1027718 | CNV | gain | 25217958 |
Disorder | Aliases | PubMed IDs |
---|---|---|
cerebellar ataxia type 48 |
|
|
attention deficit-hyperactivity disorder |
|
|