Aliases for CHMP7 Gene
External Ids for CHMP7 Gene
Previous GeneCards Identifiers for CHMP7 Gene
GeneCards Summary for CHMP7 Gene
CHMP7 (Charged Multivesicular Body Protein 7) is a Protein Coding gene. Diseases associated with CHMP7 include Cerebellar Ataxia Type 48 and Attention Deficit-Hyperactivity Disorder. Among its related pathways are Budding and maturation of HIV virion and Necroptosis. Gene Ontology (GO) annotations related to this gene include protein transporter activity. An important paralog of this gene is CHMP5.
UniProtKB/Swiss-Prot Summary for CHMP7 Gene
ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase (PubMed:26040712). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed:26040712). Plays a role in the endosomal sorting pathway (PubMed:16856878).