Aliases for CHIAP2 Gene

Aliases for CHIAP2 Gene

  • Chitinase, Acidic Pseudogene 2 2 3 5
  • CHIA-Like Pseudogene 3
  • CHIAP2 5

External Ids for CHIAP2 Gene

Previous GeneCards Identifiers for CHIAP2 Gene

  • GC01P111825

Summaries for CHIAP2 Gene

GeneCards Summary for CHIAP2 Gene

CHIAP2 (Chitinase, Acidic Pseudogene 2) is a Pseudogene. Diseases associated with CHIAP2 include Lung Cancer Susceptibility 3.

Additional gene information for CHIAP2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CHIAP2 Gene

Genomics for CHIAP2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CHIAP2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J111275 Enhancer 0.7 Ensembl ENCODE 12.8 -4.8 -4758 1.4 SCRT2 RUNX3 USF1 FOSL1 FOXA1 MNT USF2 CHIAP2 CHIA CHIAP1 DENND2D
GH01J111270 Enhancer 0.5 Ensembl 8.8 -9.6 -9558 0.2 CTBP1 USF1 HLF CBFA2T3 EZH2 CHIAP2 CHIA CHIAP1 DENND2D
GH01J111259 Enhancer 0.2 Ensembl 10.7 -19.9 -19858 0.4 CHIAP2 CHIAP1 CHIA DENND2D
GH01J111290 Promoter 0.5 EPDnew 0.4 +10.8 10774 0.1 SCRT2 YY1 CHIA CHIAP2 DENND2D
GH01J111254 Enhancer 0.3 Ensembl 0.3 -25.5 -25458 0.4 FOXA1 CHIAP1 CHIAP2 CHIA DENND2D
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CHIAP2 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for CHIAP2 Gene

Genomic Locations for CHIAP2 Gene
6,058 bases
Plus strand
6,058 bases
Plus strand

Genomic View for CHIAP2 Gene

Genes around CHIAP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CHIAP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CHIAP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CHIAP2 Gene

Proteins for CHIAP2 Gene

Post-translational modifications for CHIAP2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CHIAP2 Gene

Domains & Families for CHIAP2 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for CHIAP2 Gene

Function for CHIAP2 Gene

Phenotypes From GWAS Catalog for CHIAP2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CHIAP2 Gene

Localization for CHIAP2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CHIAP2 Gene

Pathways & Interactions for CHIAP2 Gene

PathCards logo

SuperPathways for CHIAP2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CHIAP2 Gene


No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for CHIAP2 Gene

Drugs & Compounds for CHIAP2 Gene

No Compound Related Data Available

Transcripts for CHIAP2 Gene

mRNA/cDNA for CHIAP2 Gene

2 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CHIAP2 Gene

No ASD Table

Relevant External Links for CHIAP2 Gene

GeneLoc Exon Structure for

Expression for CHIAP2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CHIAP2 Gene

mRNA differential expression in normal tissues according to GTEx for CHIAP2 Gene

This gene is overexpressed in Lung (x38.0) and Stomach (x12.0).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CHIAP2

SOURCE GeneReport for Unigene cluster for CHIAP2 Gene:

genes like me logo Genes that share expression patterns with CHIAP2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CHIAP2 Gene

Orthologs for CHIAP2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CHIAP2 Gene

Organism Taxonomy Gene Similarity Type Details
African clawed frog
(Xenopus laevis)
Amphibia chia-A-prov 30
(Danio rerio)
Actinopterygii wufb60f06 30
Species where no ortholog for CHIAP2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for CHIAP2 Gene

Gene Tree for CHIAP2 (if available)
Gene Tree for CHIAP2 (if available)

Paralogs for CHIAP2 Gene

No data available for Paralogs for CHIAP2 Gene

Variants for CHIAP2 Gene

Structural Variations from Database of Genomic Variants (DGV) for CHIAP2 Gene

Variant ID Type Subtype PubMed ID
dgv18n111 CNV deletion 26073780
esv2665968 CNV deletion 23128226
esv2758960 CNV loss 17122850
esv3587180 CNV loss 21293372
nsv1005303 CNV gain 25217958
nsv441709 CNV loss 18776908
nsv463250 CNV loss 19166990
nsv547535 CNV loss 21841781
nsv547536 CNV gain+loss 21841781

Additional Variant Information for CHIAP2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for CHIAP2 Gene

Disorders for CHIAP2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CHIAP2 Gene - From: LncRNADisease

Disorder Aliases PubMed IDs
lung cancer susceptibility 3
  • lncr3
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for CHIAP2

genes like me logo Genes that share disorders with CHIAP2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CHIAP2 Gene

Publications for CHIAP2 Gene

  1. Pseudogene CHIAP2 inhibits proliferation and invasion of lung adenocarcinoma cells by means of the WNT pathway. (PMID: 30623445) Shang J … Li S (Journal of cellular physiology 2019) 3
  2. Chitinases: biomarkers for human diseases. (PMID: 19442228) Guan SP … Wong WS (Protein and peptide letters 2009) 3
  3. Evolution of mammalian chitinase(-like) members of family 18 glycosyl hydrolases. (PMID: 17720922) Bussink AP … Boot RG (Genetics 2007) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for CHIAP2 Gene

Sources for CHIAP2 Gene