CHIAP2 Gene (Pseudogene)

Chitinase, Acidic Pseudogene 2

GC01P111280
GIFtS:
17

Aliases for CHIAP2 Gene

Aliases for CHIAP2 Gene

  • Chitinase, Acidic Pseudogene 2 2 3 5
  • CHIA-Like Pseudogene 3

External Ids for CHIAP2 Gene

Previous GeneCards Identifiers for CHIAP2 Gene

  • GC01P111825

Summaries for CHIAP2 Gene

GeneCards Summary for CHIAP2 Gene

CHIAP2 (Chitinase, Acidic Pseudogene 2) is a Pseudogene. Diseases associated with CHIAP2 include Lung Cancer Susceptibility 3.

Additional gene information for CHIAP2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CHIAP2 Gene

Genomics for CHIAP2 Gene

GeneHancer (GH) Regulatory Elements for CHIAP2 Gene

Promoters and enhancers for CHIAP2 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH01J111275 Enhancer 0.7 Ensembl ENCODE 12.8 -4.8 -4758 1.4 MNT SCRT2 RUNX3 USF1 FOSL1 FOXA1 CHIAP2 CHIA CHIAP1
GH01J111270 Enhancer 0.4 Ensembl 8.8 -9.6 -9558 0.2 HLF CTBP1 USF1 CBFA2T3 CHIAP2 CHIAP1
GH01J111259 Enhancer 0.2 Ensembl 10.7 -19.9 -19858 0.4 CHIAP2 CHIAP1
GH01J111290 Promoter 0.5 EPDnew 0.4 +10.8 10774 0.1 SCRT2 YY1 CHIA CHIAP2
GH01J111251 Enhancer 0.2 Ensembl 0.3 -28.3 -28258 1.6 CHIAP1 CHI3L2 CHIAP2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CHIAP2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CHIAP2 Gene

Genomic Locations for CHIAP2 Gene
chr1:111,280,059-111,286,116
(GRCh38/hg38)
Size:
6,058 bases
Orientation:
Plus strand
chr1:111,822,681-111,828,738
(GRCh37/hg19)
Size:
6,058 bases
Orientation:
Plus strand

Genomic View for CHIAP2 Gene

Genes around CHIAP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CHIAP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CHIAP2 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for CHIAP2 Gene

Proteins for CHIAP2 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for CHIAP2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CHIAP2 Gene

Domains & Families for CHIAP2 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for CHIAP2 Gene

Function for CHIAP2 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for CHIAP2 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CHIAP2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CHIAP2 Gene

Localization for CHIAP2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CHIAP2 Gene

Pathways & Interactions for CHIAP2 Gene

PathCards logo

SuperPathways for CHIAP2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CHIAP2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CHIAP2 Gene

Drugs & Compounds for CHIAP2 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for CHIAP2 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for CHIAP2 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CHIAP2

Alternative Splicing Database (ASD) splice patterns (SP) for CHIAP2 Gene

No ASD Table

Relevant External Links for CHIAP2 Gene

GeneLoc Exon Structure for
CHIAP2
ECgene alternative splicing isoforms for
CHIAP2

Expression for CHIAP2 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CHIAP2 Gene

mRNA expression in normal human tissues for CHIAP2 Gene
mRNA expression by GTEx for CHIAP2 Gene

mRNA differential expression in normal tissues according to GTEx for CHIAP2 Gene

This gene is overexpressed in Lung (x38.0) and Stomach (x12.0).

NURSA nuclear receptor signaling pathways regulating expression of CHIAP2 Gene:

CHIAP2

SOURCE GeneReport for Unigene cluster for CHIAP2 Gene:

Hs.736960
genes like me logo Genes that share expression patterns with CHIAP2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CHIAP2 Gene

Orthologs for CHIAP2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CHIAP2 Gene

Organism Taxonomy Gene Similarity Type Details
African clawed frog
(Xenopus laevis)
 Amphibia chia-A-prov 32
zebrafish
(Danio rerio)
 Actinopterygii wufb60f06 32
Species where no ortholog for CHIAP2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CHIAP2 Gene

ENSEMBL:
Gene Tree for CHIAP2 (if available)
TreeFam:
Gene Tree for CHIAP2 (if available)

Paralogs for CHIAP2 Gene

No data available for Paralogs for CHIAP2 Gene

Variants for CHIAP2 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for CHIAP2 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000236729 -- 111,280,170(+) T/G upstream_transcript_variant
rs1000360764 -- 111,285,144(+) G/A non_coding_transcript_variant
rs1000515856 -- 111,281,262(+) A/G intron_variant
rs1000569761 -- 111,281,497(+) A/T intron_variant
rs1001101031 -- 111,286,306(+) C/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CHIAP2 Gene

Variant ID Type Subtype PubMed ID
dgv18n111 CNV deletion 26073780
esv2665968 CNV deletion 23128226
esv2758960 CNV loss 17122850
esv3587180 CNV loss 21293372
nsv1005303 CNV gain 25217958
nsv441709 CNV loss 18776908
nsv463250 CNV loss 19166990
nsv547535 CNV loss 21841781
nsv547536 CNV gain+loss 21841781

Additional Variant Information for CHIAP2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CHIAP2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CHIAP2 Gene

Disorders for CHIAP2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CHIAP2 Gene - From: LncRNADisease

Disorder Aliases PubMed IDs
lung cancer susceptibility 3
  • lncr3
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for CHIAP2

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with CHIAP2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CHIAP2 Gene

Publications for CHIAP2 Gene

  1. Chitinases: biomarkers for human diseases. (PMID: 19442228) Guan SP … Wong WS (Protein and peptide letters 2009) 3 56
  2. Evolution of mammalian chitinase(-like) members of family 18 glycosyl hydrolases. (PMID: 17720922) Bussink AP … Boot RG (Genetics 2007) 3 56
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 56

ExternalLinks

View latest publications for CHIAP2 gene in Mastermind

Products for CHIAP2 Gene

Sources for CHIAP2 Gene