Aliases for CHAD Gene
External Ids for CHAD Gene
Previous GeneCards Identifiers for CHAD Gene
Chondroadherin is a cartilage matrix protein thought to mediate adhesion of isolated chondrocytes. The protein contains 11 leucine-rich repeats flanked by cysteine-rich regions. The chondroadherin messenger RNA is present in chondrocytes at all ages. [provided by RefSeq, Jul 2008]
GeneCards Summary for CHAD Gene
CHAD (Chondroadherin) is a Protein Coding gene. Diseases associated with CHAD include Calcific Tendinitis and Autonomic Peripheral Neuropathy. Among its related pathways are Focal Adhesion and PI3K-Akt signaling pathway. An important paralog of this gene is CHADL.
UniProtKB/Swiss-Prot Summary for CHAD Gene
Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation (By similarity).