Free for academic non-profit institutions. Other users need a Commercial license
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The p... See more...
Aliases for CGA Gene
Aliases for CGA Gene
- Glycoprotein Hormones, Alpha Polypeptide 2 3 5
- Thyroid-Stimulating Hormone Alpha Chain 2 3 4
- Glycoprotein Hormones Alpha Chain 2 3 4
- Luteinizing Hormone Alpha Chain 2 3 4
- Lutropin Alpha Chain 2 3 4
- Anterior Pituitary Glycoprotein Hormones Common Subunit Alpha 3 4
- Follicle-Stimulating Hormone Alpha Subunit 2 3
- Chorionic Gonadotropin, Alpha Polypeptide 2 3
- Follicle-Stimulating Hormone Alpha Chain 3 4
- Chorionic Gonadotrophin Subunit Alpha 3 4
- Choriogonadotropin Alpha Chain 3 4
- Follitropin Alpha Chain 3 4
- Thyrotropin Alpha Chain 3 4
External Ids for CGA Gene
- HGNC: 1885
- NCBI Entrez Gene: 1081
- Ensembl: ENSG00000135346
- OMIM®: 118850
- UniProtKB/Swiss-Prot: P01215
Previous GeneCards Identifiers for CGA Gene
- GC06M087741
- GC06M087790
- GC06M087851
- GC06M087795
- GC06M085012
Summaries for CGA Gene
-
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
GeneCards Summary for CGA Gene
CGA (Glycoprotein Hormones, Alpha Polypeptide) is a Protein Coding gene. Diseases associated with CGA include Ectopic Pregnancy and Ovarian Hyperstimulation Syndrome. Among its related pathways are Signaling by GPCR and Human Thyroid Stimulating Hormone (TSH) signaling pathway. Gene Ontology (GO) annotations related to this gene include hormone activity.
UniProtKB/Swiss-Prot Summary for CGA Gene
-
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
Additional gene information for CGA Gene
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CGA Gene
Genomics for CGA Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CGA Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CGA on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CGA
- Top Transcription factor binding sites by QIAGEN in the CGA gene promoter:
-
- AML1a
- CREB
- deltaCREB
- En-1
Genomic Locations for CGA Gene
Latest Assembly
- chr6:87,085,498-87,095,106
- (GRCh38/hg38)
- Size:
- 9,609 bases
- Orientation:
- Minus strand
Previous Assembly
- chr6:87,795,216-87,804,824
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 9,609 bases
- Orientation:
- Minus strand
Genomic View for CGA Gene
Genes around CGA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6q14.3 by HGNC
- 6q14.3 by Entrez Gene
- 6q14.3 by Ensembl
CGA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CGA Gene
Proteins for CGA Gene
-
Protein details for CGA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P01215-GLHA_HUMAN
- Recommended name:
- Glycoprotein hormones alpha chain
- Protein Accession:
- P01215
Protein attributes for CGA Gene
- Size:
- 116 amino acids
- Molecular mass:
- 13075 Da
- Quaternary structure:
-
- Heterodimer. The active hormones thyrotropin, lutropin, follitropin and choriogonadotropin are heterodimers composed of CGA, a common alpha chain described here and a unique beta chain which confers their biological specificity to the hormones: TSHB for thyrotropin, LHB for lutropin, FSHB for follitropin and choriogonadotropin subunit beta/CGB for choriogonadotropin.
Protein Expression for CGA Gene
Post-translational modifications for CGA Gene
Other Protein References for CGA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences CGA / hCG Alpha Monoclonal Antibody and CGA / hCG Alpha Antibody
- G Biosciences Immunotag™ hCG (ABT-HCG) mouse mAb and Immunotag™ CGA Antibody
-
Custom Antibody ServicesOriGene Antibodies for CGA
- Novus Biologicals Antibodies for CGA
-
Abcam antibodies for CGA
- Invitrogen Antibodies for CGA (AFLGC-CGA)
-
Biorbyt antibodies for CGA
-
Custom Antibody ServicesProSci Antibodies for CGA
- glycoprotein hormones, alpha polypeptide [14-394]
- Glycoprotein hormones alpha chain [34-094]
- Glycoprotein hormones alpha chain [56-122]
- glycoprotein hormones, alpha polypeptide [33-112]
- glycoprotein hormones, alpha polypeptide [33-525]
- Glycoprotein hormones alpha chain [33-645]
- glycoprotein hormones, alpha polypeptide [33-872]
-
Santa Cruz Biotechnology (SCBT) Antibodies for CGA
- Sino Biological Antibodies for CGA
Protein products for research
-
OriGene Purified Proteins for CGA
- Search Origene for MassSpec and Protein Over-expression Lysates for CGA
- Origene Custom Protein Services for CGA
- Sino Biological Recombinant Proteins for CGA
- Sino Biological Cell Lysates for CGA
- antibodies-online: Show 10 available hCG-a Proteins ranked by validation data
- Compare Top hCG-a Proteins
-
Quality Products:
-
ProSci Proteins for CGA
-
Abcam proteins for CGA
Assay products for research
- G Biosciences Immunotag™ Glycoprotein hormones alpha chain ELISA Kit
- Novus Biologicals ELISA Kits for CGA
- antibodies-online: Show 53 available hCG-a Elisa Kits ranked by validation data
- Compare Top hCG-a Elisa Kits
-
Quality Products:
- ABIN1114143
- ABIN840350
- ABIN417683
- ABIN1980580
- ABIN5525596
- ABIN5525597
- ABIN5669601
- ABIN1568968
- ABIN5595244
- ABIN5652938
- ABIN5525598
- ABIN840351
- ABIN455751
- ABIN2947969
- ABIN5595245
- ABIN5072001
- ABIN5525599
- ABIN578868
- ABIN840352
- ABIN5595247
- ABIN2947970
- ABIN5071440
- ABIN578867
- ABIN5595246
- ABIN1560482
- ABIN6233817
- Sino Biological Assays for CGA
No data available for DME Specific Peptides for CGA Gene
Domains & Families for CGA Gene
Gene Families for CGA Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted secreted proteins
Protein Domains for CGA Gene
- InterPro:
- Blocks:
-
- Growth factor cystine knot superfamily signature
- Glycoprotein hormones alpha chain
Suggested Antigen Peptide Sequences for CGA Gene
- GenScript: Design optimal peptide antigens:
-
- Follicle-stimulating hormone alpha subunit (C0KRQ8_HUMAN)
- Thyrotropin alpha chain (GLHA_HUMAN)
- cDNA, FLJ92245, Homo sapiens glycoprotein hormones, alpha polypeptide (CGA), mRNA (Q6I9S8_HUMAN)
- Glycoprotein hormones, alpha polypeptide (Q96QJ4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P01215- Family:
-
- Belongs to the glycoprotein hormones subunit alpha family.
Function for CGA Gene
Molecular function for CGA Gene
- UniProtKB/Swiss-Prot Function:
- Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
- GENATLAS Biochemistry:
- glycoprotein hormones,alpha polypeptide,common to chorionic gonadotropin,FSH,LH,TSH
Phenotypes From GWAS Catalog for CGA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005179 | hormone activity | IEA,IMP | 11207219 |
| GO:0005515 | protein binding | IPI | 7922031 |
| GO:0016913 | follicle-stimulating hormone activity | IDA | 2494176 |
Phenotypes for CGA Gene
- MGI mutant phenotypes for CGA:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CGA:
Animal Models for CGA Gene
- MGI Knock Outs for CGA:
-
- Cga Cga<tm1Sac>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for CGA - Starting at $85 >
- * CGA CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for CGA
-
Santa Cruz Biotechnology (SCBT) CRISPR for CGA
miRNA for CGA Gene
- miRTarBase miRNAs that target CGA
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CGA
- Browse OriGene Inhibitory RNA Products For CGA
Clone products for research
- Applied Biological Materials (abm): Clones for CGA - Starting at $45 >
- * CGA as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for CGA
Cell Lines for research
-
Horizon Cell Lines for CGA
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CGA Gene
Localization for CGA Gene
Subcellular locations from UniProtKB/Swiss-Prot for CGA Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| golgi apparatus | 4 |
| plasma membrane | 2 |
| cytoskeleton | 2 |
| nucleus | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA,TAS | -- |
| GO:0005615 | extracellular space | IBA,IDA | 2494176 |
| GO:0005796 | Golgi lumen | TAS | -- |
| GO:0016914 | follicle-stimulating hormone complex | IDA | 2494176 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CGA Gene
Pathways & Interactions for CGA Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Peptide ligand-binding receptors | ||
| 2 | Metabolism of steroid hormones | ||
| 3 | Peptide hormone metabolism | ||
| 4 | Signaling by GPCR | ||
| 5 | Amine-derived hormones | ||
Pathways by source for CGA Gene
4 BioSystems pathways for CGA Gene
28 Reactome pathways for CGA Gene
9 KEGG pathways for CGA Gene
2 GeneGo (Thomson Reuters) pathways for CGA Gene
- Development Role of Activin A in cell differentiation and proliferation
- Transcription_Role of VDR in regulation of genes involved in osteoporosis
1 Qiagen pathway for CGA Gene
- GnRH Signaling
Interacting Proteins for CGA Gene
Selected Interacting proteins:
P01215-GLHA_HUMAN
ENSP00000482232
for CGA Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for CGA
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006357 | regulation of transcription by RNA polymerase II | TAS | -- |
| GO:0006590 | thyroid hormone generation | IBA | 21873635 |
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G protein-coupled receptor signaling pathway | TAS | -- |
| GO:0008284 | positive regulation of cell proliferation | NAS | 20613903 |
Drugs & Compounds for CGA Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Levoleucovorin | Approved, Investigational | Pharma | 3859,989 | |||
| Cetuximab | Approved | Pharma | EGFR Inhibitors, Therapeutic Antibodies, Epidermal growth factor receptor (EGFR) inhibitors | 902 | ||
| Fluorouracil | Approved | Pharma | RNA processing inhibitor and thymidylate synthase inhibitor | 2449 | ||
| leucovorin | Approved | Pharma | 1627 | |||
| Folic acid | Approved, Vet_approved | Nutra | 5007 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
(1) ApexBio Compounds for CGA Gene
| Compound | Action | Cas Number |
|---|---|---|
| Luteinizing hormone releasing hormone human acetate salt (LHRH) | 71447-49-9 |
Drug products for research
- ApexBio compounds for CGA
Transcripts for CGA Gene
mRNA/cDNA for CGA Gene
- 2 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000369582 729 nts (view in UCSC)
- ENST00000610310 615 nts (view in UCSC)
- ENST00000625577 587 nts (view in UCSC)
- ENST00000627148 710 nts (view in UCSC)
- ENST00000627552 601 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for CGA - Starting at $85 >
- * CGA CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for CGA
-
Santa Cruz Biotechnology (SCBT) CRISPR for CGA
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CGA
- Browse OriGene Inhibitory RNA Products For CGA
Clone products for research
- Applied Biological Materials (abm): Clones for CGA - Starting at $45 >
- * CGA as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for CGA
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | · | 6c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||
| SP5: | - |
Relevant External Links for CGA Gene
- GeneLoc Exon Structure for
- CGA
Expression for CGA Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Placenta (Extraembryonic Tissues)
- Trophoblast (Extraembryonic Tissues)
- Endocrine System (Endocrine System)
- Uncategorized
- NULL (Uncategorized)
- Brain (Nervous System)
- Liver (Hepatobiliary System)
mRNA differential expression in normal tissues according to GTEx for CGA Gene
This gene is overexpressed in Pituitary (x52.6).
This gene is overexpressed in Placenta (65.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CGA Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CGA
SOURCE GeneReport for Unigene cluster for CGA Gene:
Hs.119689Evidence on tissue expression from TISSUES for CGA Gene
- Nervous system(4.4)
- Stomach(2.2)
- Lung(2.1)
Primer products for research
-
OriGene qPCR primer pairs for CGA
-
OriGene qPCR primer pairs and template standards for CGA
Gene Expression Assays for research
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CGA Gene
Orthologs for CGA Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | CGA 29 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | CGA 29 30 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | CGA 29 30 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Cga 29 16 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Cga 29 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | CGA 30 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | CGA 30 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | CGA 29 30 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | CGA 30 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | cga 29 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | tsha-A 29 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | cga 29 30 |
|
OneToOne | |
| Dr.13896 29 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.11927 29 |
|
- Species where no ortholog for CGA was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for CGA Gene
- ENSEMBL:
- Gene Tree for CGA (if available)
- TreeFam:
- Gene Tree for CGA (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CGA: view image
- Alliance of Genome Resources:
- Additional Orthologs for CGA
Paralogs for CGA Gene
No data available for Paralogs for CGA Gene
Variants for CGA Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CGA Gene
| SNP ID | Clinical significance and condition | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs143780652 | Benign: not provided | 87,085,839(-) |
G/A NM_000735.4(CGA):c.274-6C>T |
INTRON | |
| rs148435935 | Benign: not provided | 87,086,295(-) |
G/A NM_000735.4(CGA):c.228C>T (p.Asn76=) |
SYNONYMOUS | |
| rs781108998 | Likely Benign: not provided | 87,086,328(-) |
T/C NM_000735.4(CGA):c.195A>G (p.Leu65=) |
SYNONYMOUS |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1002835 | CNV | deletion | 20482838 |
| esv2763585 | CNV | gain | 21179565 |
| nsv5385 | CNV | deletion | 18451855 |
| nsv604106 | CNV | gain | 21841781 |
Residual Variation Intolerance Score:
43.1% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CGA Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CGA Gene
Disorders for CGA Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ectopic pregnancy |
|
|
| ovarian hyperstimulation syndrome |
|
|
| triploidy |
|
|
| ovarian remnant syndrome |
|
|
| ovarian disease |
|
|
Search CGA in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CGA
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for CGA Gene
Publications for CGA Gene
- The gene encoding the common alpha subunit of the four human glycoprotein hormones. (PMID: 6286817) Fiddes JC … Goodman HM (Journal of molecular and applied genetics 1981) 2 3 4
- Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer. (PMID: 24692546) Jiang X … He X (The Journal of biological chemistry 2014) 3 4
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 40
- A large-scale candidate gene association study of age at menarche and age at natural menopause. (PMID: 20734064) He C … Hunter DJ (Human genetics 2010) 3 40
- Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium. (PMID: 20634197) Canzian F … Feigelson HS (Human molecular genetics 2010) 3 40
ExternalLinks
Products for CGA Gene
- View all 3 R&D Systems CGA (Chorionic Gonadotropin alpha Chain (HCG alpha)) Products
- View all R&D Systems CGA (Chorionic Gonadotropin alpha Chain (HCG alpha)) Proteins and Enzymes
- View all 2 R&D Systems CGA (Chorionic Gonadotropin alpha Chain (HCG alpha)) Primary Antibodies
- Learn more about R&D Systems custom CGA antibody, protein, and immunoassay development services
- Custom Antibody ServicesOriGene Antibodies for CGA
- Custom Assay Services
- OriGene Purified Proteins for CGA
- Search Origene for MassSpec and Protein Over-expression Lysates for CGA
- Origene Custom Protein Services for CGA
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CGA
- Browse OriGene Inhibitory RNA Products For CGA
- OriGene qPCR primer pairs for CGA
- OriGene qPCR primer pairs and template standards for CGA
- OriGene CRISPR knockouts for CGA
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CGA
- Sino Biological Human cDNA Clone for CGA
- Sino Biological Recombinant Proteins for CGA
- Sino Biological Cell Lysates for CGA
- Sino Biological Antibodies for CGA
- Sino Biological Assays for CGA
- Browse Antibodies
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for CGA
- Novus Biologicals proteins and lysates for CGA
- Novus Biologicals ELISA Kits for CGA
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for CGA
- Abcam proteins for CGA
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for CGA (AFLGC-CGA)
- ApexBio compounds for CGA
- VectorBuilder Custom and pre-made DNA vectors for CGA (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for CGA (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for CGA (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for CGA CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for CGA
- antibodies-online: Show 9 available hCG-a Antibodies ranked by validation data
- Compare Top hCG-a Antibodies
- antibodies-online: Show 53 available hCG-a Elisa Kits ranked by validation data
- Compare Top hCG-a Elisa Kits
- Quality Products:
- ABIN1114143
- ABIN840350
- ABIN417683
- ABIN1980580
- ABIN5525596
- ABIN5525597
- ABIN5669601
- ABIN1568968
- ABIN5595244
- ABIN5652938
- ABIN5525598
- ABIN840351
- ABIN455751
- ABIN2947969
- ABIN5595245
- ABIN5072001
- ABIN5525599
- ABIN578868
- ABIN840352
- ABIN5595247
- ABIN2947970
- ABIN5071440
- ABIN578867
- ABIN5595246
- ABIN1560482
- ABIN6233817
- antibodies-online: Show 10 available hCG-a Proteins ranked by validation data
- Compare Top hCG-a Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for CGA
- Search Santa Cruz Biotechnology (SCBT) for CGA siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CGA
- Custom Antibody ServicesProSci Antibodies for CGA
- glycoprotein hormones, alpha polypeptide [14-394]
- Glycoprotein hormones alpha chain [34-094]
- Glycoprotein hormones alpha chain [56-122]
- glycoprotein hormones, alpha polypeptide [33-112]
- glycoprotein hormones, alpha polypeptide [33-525]
- Glycoprotein hormones alpha chain [33-645]
- glycoprotein hormones, alpha polypeptide [33-872]
- ProSci Proteins for CGA
- Horizon Cell Lines for CGA
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for CGA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for CGA
- Search GeneCopoeia for miRNA 3'UTR Target clone products for CGA
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for CGA
- Biorbyt antibodies for CGA
Sources for CGA Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources