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This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations i... See more...
Aliases for CFP Gene
Aliases for CFP Gene
External Ids for CFP Gene
- HGNC: 8864
- Entrez Gene: 5199
- Ensembl: ENSG00000126759
- OMIM: 300383
- UniProtKB: P27918
Previous HGNC Symbols for CFP Gene
- PFC
Previous GeneCards Identifiers for CFP Gene
- GC0XM047368
- GC0XM047484
- GC0XM045196
Summaries for CFP Gene
-
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009]
GeneCards Summary for CFP Gene
CFP (Complement Factor Properdin) is a Protein Coding gene. Diseases associated with CFP include Properdin Deficiency, X-Linked and Properdin Deficiency. Among its related pathways are Metabolism of proteins and Innate Immune System.
UniProtKB/Swiss-Prot Summary for CFP Gene
-
A positive regulator of the alternate pathway (AP) of complement (PubMed:20382442, PubMed:28264884). It binds to and stabilizes the C3- and C5-convertase enzyme complexes (PubMed:20382442, PubMed:28264884). Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b) (PubMed:31507604).
Additional gene information for CFP Gene
- HGNC(8864)
- Entrez Gene(5199)
- Ensembl(ENSG00000126759)
- OMIM(300383)
- UniProtKB(P27918)
- Open Targets Platform(ENSG00000126759)
- Monarch Initiative
- Search for CFP at DataMed
- Search for CFP at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CFP Gene
Genomics for CFP Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CFP Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CFP on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CFP
- Top Transcription factor binding sites by QIAGEN in the CFP gene promoter:
-
- CREB
- deltaCREB
- NRSF form 1
- NRSF form 2
- STAT3
Genomic Locations for CFP Gene
Genomic Locations for CFP Gene
- chrX:47,623,172-47,630,305
- (GRCh38/hg38)
- Size:
- 7,134 bases
- Orientation:
- Minus strand
- chrX:47,483,612-47,489,704
- (GRCh37/hg19)
- Size:
- 6,093 bases
- Orientation:
- Minus strand
Genomic View for CFP Gene
Genes around CFP on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp11.23 by HGNC
- Xp11.23 by Entrez Gene
- Xp11.23 by Ensembl
CFP Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CFP Gene
Proteins for CFP Gene
-
Protein details for CFP Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P27918-PROP_HUMAN
- Recommended name:
- Properdin
- Protein Accession:
- P27918
- O15134
- O15135
- O15136
- O75826
Protein attributes for CFP Gene
- Size:
- 469 amino acids
- Molecular mass:
- 51276 Da
- Quaternary structure:
-
- In plasma, properdin exists as dimers, trimers or tetramers in the relative proportions of 26:54:20 (PubMed:20382442, PubMed:15491616, PubMed:28264884, PubMed:31507604). Interacts with the pro-C3-convertase enzyme complex (C3b-Bb) comprised of Complement C3 beta chain (C3b) and the Complement factor B Bb fragment (Bb), where it binds (via its TSP type-1 5 domain) with C3b and Bb (PubMed:28264884, PubMed:31507604). This interaction stabilizes the complex and allows it to become the active C3-convertase enzyme complex (C3b-Bb-FP) (PubMed:28264884, PubMed:31507604). Interacts with C3b (PubMed:28264884, PubMed:31507604). Interacts with CFB (PubMed:31507604).
Protein Expression for CFP Gene
Post-translational modifications for CFP Gene
Other Protein References for CFP Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences Properdin / CFP Antibody (LS-B6914) and Properdin / CFP Antibody (LS-B13878)
- G Biosciences Immunotag™ CFP Antibody
- NSJ Bioreagents CFP Antibody
-
Custom Antibody ServicesOriGene Antibodies for CFP
- Novus Biologicals Antibodies for CFP
-
Abcam antibodies for CFP
- Invitrogen Antibodies for CFP (AFLGC-CFP)
- antibodies-online: Show 53 available CFP Antibodies ranked by validation data
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-
Recommended
- 78 WB Antibodies (anti-human)
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- 6 IHC Antibodies (anti-human)
- 4 RIA Antibodies (anti-human)
- 2 FACS Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 1 EIA Antibody (anti-human)
- 1 ID Antibody (anti-human)
- 1 RID Antibody (anti-human)
- 23 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-rat)
- 10 WB Antibodies (anti-rat)
-
Boster Bio Antibodies for CFP
-
Santa Cruz Biotechnology (SCBT) Antibodies for CFP
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for CFP
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- Novus Biologicals lysates for CFP
- ProSpec Recombinant Proteins for CFP
- antibodies-online: Show 17 available CFP Proteins ranked by validation data
- Compare Top CFP Proteins
-
Signalway Proteins for CFP
-
Abcam proteins for CFP
Assay Products
- G Biosciences Immunotag™ Human CFP (Properdin) ELISA and Immunotag™ Properdin ELISA Kit
- RayBiotech Human Properdin ELISA
-
Custom Assay ServicesOriGene ELISA Kits for CFP
- Novus Biologicals ELISA Kits for CFP
-
Boster Bio ELISA Kits for CFP
No data available for DME Specific Peptides for CFP Gene
Domains & Families for CFP Gene
Gene Families for CFP Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for CFP Gene
- InterPro:
- Blocks:
-
- Thrombospondin, type I
- Thrombospondin type 1 repeat signature
- ProtoNet:
Suggested Antigen Peptide Sequences for CFP Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ16673 fis, clone THYMU3003403, highly similar to Properdin (B3KVK6_HUMAN)
- Complement factor P (PROP_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P27918UniProtKB/Swiss-Prot:
PROP_HUMAN :- TSP type-1 domain 0 binds to TSP type-1 domain 4, and TSP type-1 domain 1 binds to TSP type-1 domain 6 (PubMed:15491616, PubMed:28264884, PubMed:31507604). These interactions mediate multimerization (PubMed:15491616, PubMed:28264884, PubMed:31507604).
- Domain:
-
- TSP type-1 domain 0 binds to TSP type-1 domain 4, and TSP type-1 domain 1 binds to TSP type-1 domain 6 (PubMed:15491616, PubMed:28264884, PubMed:31507604). These interactions mediate multimerization (PubMed:15491616, PubMed:28264884, PubMed:31507604).
Function for CFP Gene
Molecular function for CFP Gene
- UniProtKB/Swiss-Prot Function:
- A positive regulator of the alternate pathway (AP) of complement (PubMed:20382442, PubMed:28264884). It binds to and stabilizes the C3- and C5-convertase enzyme complexes (PubMed:20382442, PubMed:28264884). Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b) (PubMed:31507604).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 22518841 |
Phenotypes for CFP Gene
- MGI mutant phenotypes for CFP:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for CFP:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CFP - Select products 50% OFF >
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-
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-
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miRNA for CFP Gene
- miRTarBase miRNAs that target CFP
miRNA Products
Inhibitory RNA Products
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Clone Products
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- Sino Biological Human cDNA Clone for CFP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CFP
Cell Line Products
-
Horizon Cell Lines for CFP
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Transcription Factor Targets and HOMER Transcription for CFP Gene
Localization for CFP Gene
Subcellular locations from UniProtKB/Swiss-Prot for CFP Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| endoplasmic reticulum | 4 |
| plasma membrane | 3 |
| cytoskeleton | 2 |
| nucleus | 2 |
| cytosol | 2 |
| mitochondrion | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | TAS,IEA | -- |
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
| GO:0030141 | secretory granule | IEA | -- |
| GO:0035580 | specific granule lumen | TAS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CFP Gene
Pathways & Interactions for CFP Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Innate Immune System |
.61
|
|
| 2 | Complement Pathway |
Alternative Complement Pathway
.01
|
|
| 3 | O-glycosylation of TSR domain-containing proteins | ||
| 4 | Diseases of glycosylation | ||
| 5 | Metabolism of proteins | ||
Pathways by source for CFP Gene
1 BioSystems pathway for CFP Gene
11 Reactome pathways for CFP Gene
1 KEGG pathway for CFP Gene
1 GeneGo (Thomson Reuters) pathway for CFP Gene
- Immune response Alternative complement pathway
1 Qiagen pathway for CFP Gene
- Alternative Complement Pathway
Interacting Proteins for CFP Gene
Selected Interacting proteins:
P27918-PROP_HUMAN
ENSP00000247153
for CFP Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for CFP
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002376 | immune system process | IEA | -- |
| GO:0006955 | immune response | TAS | 8530058 |
| GO:0006956 | complement activation | TAS | -- |
| GO:0006957 | complement activation, alternative pathway | TAS | -- |
| GO:0030449 | regulation of complement activation | TAS | -- |
No data available for SIGNOR curated interactions for CFP Gene
Transcripts for CFP Gene
mRNA/cDNA for CFP Gene
- 2 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000640573 2751 nts (view in UCSC)
- ENST00000478222 593 nts (view in UCSC)
- ENST00000396992 1592 nts (view in UCSC)
- ENST00000485991 4040 nts (view in UCSC)
- ENST00000377005 1435 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CFP - Select products 50% OFF >
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-
OriGene CRISPR knockouts for CFP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CFP
-
Santa Cruz Biotechnology (SCBT) CRISPR for CFP
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CFP
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Clone Products
- Applied Biological Materials (abm): Clones for CFP - Select products 50% OFF >
- * CFP as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Sino Biological Human cDNA Clone for CFP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CFP
Relevant External Links for CFP Gene
- GeneLoc Exon Structure for
- CFP
Expression for CFP Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for CFP Gene
This gene is overexpressed in Whole Blood (x37.4) and Spleen (x6.2).
This gene is overexpressed in Serum (26.5), Plasma (16.3), Cervix (12.3), and Synovial fluid (8.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CFP Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CFP
SOURCE GeneReport for Unigene cluster for CFP Gene:
Hs.53155Evidence on tissue expression from TISSUES for CFP Gene
- Spleen(4.6)
- Bone marrow(4.5)
- Blood(3.4)
- Liver(2.7)
- Intestine(2.5)
- Lymph node(2.5)
- Heart(2.4)
- Nervous system(2.4)
- Skin(2.3)
- Kidney(2.2)
- Lung(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for CFP Gene
Germ Layers:
- endoderm
Systems:
- immune
Regions:
Abdomen:
- liver
General:
- blood
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for CFP
-
OriGene qPCR primer pairs and template standards for CFP
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt for CFP Gene
Orthologs for CFP Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | CFP 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | CFP 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | CFP 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Cfp 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Cfp 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | CFP 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | CFP 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | CFP 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | cfp 30 31 |
|
OneToMany | |
| CFP (1 of 2) 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | unc-5 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | unc-5 31 |
|
ManyToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.8480 31 |
|
ManyToMany |
- Species where no ortholog for CFP was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
Evolution for CFP Gene
- ENSEMBL:
- Gene Tree for CFP (if available)
- TreeFam:
- Gene Tree for CFP (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CFP: view image
Paralogs for CFP Gene
(4) SIMAP similar genes for CFP Gene using alignment to 5 proteins:
- PROP_HUMAN
- B3KVK6_HUMAN
- C9J7V5_HUMAN
- E9PAQ1_HUMAN
- L0R836_HUMAN
No data available for Paralogs for CFP Gene
Variants for CFP Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CFP Gene
| SNP ID | Clinical significance and condition | Chr 0X pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 713258 | Benign: not provided | 47,627,159(-) | C/T | MISSENSE_VARIANT | |
| 723100 | Likely Benign: not provided | 47,626,175(-) | A/G | INTRON_VARIANT | |
| 726140 | Benign: not provided | 47,626,818(-) | C/T | MISSENSE_VARIANT | |
| 728910 | Benign: not provided | 47,629,594(-) | C/T | MISSENSE_VARIANT | |
| 729229 | Benign: not provided | 47,627,296(-) | G/A | MISSENSE_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1141672 | CNV | duplication | 24896259 |
| nsv438130 | CNV | loss | 16468122 |
Residual Variation Intolerance Score:
57.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.87;
34.93% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CFP Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CFP Gene
Disorders for CFP Gene
(39) MalaCards diseases for CFP Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| properdin deficiency, x-linked |
|
|
| properdin deficiency |
|
|
| complement deficiency |
|
|
| acute poststreptococcal glomerulonephritis |
|
|
| meningococcal meningitis |
|
Search CFP in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
PROP_HUMAN- Properdin deficiency (PFD) [MIM:312060]: Results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III). {ECO:0000269 PubMed:10909851, ECO:0000269 PubMed:28264884, ECO:0000269 PubMed:31507604, ECO:0000269 PubMed:8871668, ECO:0000269 PubMed:9710744}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for CFP
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for Genatlas for CFP Gene
Publications for CFP Gene
- Properdin, the positive regulator of complement, is highly C-mannosylated. (PMID: 10878002) Hartmann S … Hofsteenge J (The Journal of biological chemistry 2000) 3 4 23
- Molecular characterisation of 10 Dutch properdin type I deficient families: mutation analysis and X-inactivation studies. (PMID: 10909851) van den Bogaard R … Mannens MM (European journal of human genetics : EJHG 2000) 3 4 23
- Expression of properdin in complete and incomplete deficiency: normal in vitro synthesis by monocytes in two cases with properdin deficiency type II due to distinct mutations. (PMID: 9710744) Fredrikson GN … Truedsson L (Journal of clinical immunology 1998) 3 4 23
- Molecular characterization of properdin deficiency type III: dysfunction produced by a single point mutation in exon 9 of the structural gene causing a tyrosine to aspartic acid interchange. (PMID: 8871668) Fredrikson GN … Truedsson L (Journal of immunology (Baltimore, Md. : 1950) 1996) 3 4 23
- Sequence-based analysis of properdin deficiency: identification of point mutations in two phenotypic forms of an X-linked immunodeficiency. (PMID: 8530058) Westberg J … Uhlén M (Genomics 1995) 3 4 23
ExternalLinks
Products for CFP Gene
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- OriGene qPCR primer pairs for CFP
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- High-throughput Antibody Production Service
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- antibodies-online: Show 53 available CFP Antibodies ranked by validation data
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- Recommended
- 78 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
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- 6 IHC Antibodies (anti-human)
- 4 RIA Antibodies (anti-human)
- 2 FACS Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 1 EIA Antibody (anti-human)
- 1 ID Antibody (anti-human)
- 1 RID Antibody (anti-human)
- 23 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-rat)
- 10 WB Antibodies (anti-rat)
- antibodies-online: Show 49 available CFP Elisa Kits ranked by validation data
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- antibodies-online: Show 17 available CFP Proteins ranked by validation data
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- Santa Cruz Biotechnology (SCBT) Antibodies for CFP
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- Santa Cruz Biotechnology (SCBT) CRISPR for CFP
- Horizon Cell Lines for CFP
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CFP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CFP
- Search GeneCopoeia for miRNA 3'UTR Target clone products for CFP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CFP
Sources for CFP Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB