Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CFH Gene

Aliases for CFH Gene

  • Complement Factor H 2 3 5
  • Age-Related Maculopathy Susceptibility 1 2 3
  • H Factor 2 (Complement) 2 3
  • H Factor 1 (Complement) 2 3
  • Beta-1H 2 3
  • HF1 3 4
  • HF2 3 4
  • HF 3 4
  • Adrenomedullin Binding Protein 3
  • Beta-1-H-Globulin 3
  • Factor H-Like 1 3
  • H Factor 1 4
  • Factor H 3
  • AHUS1 3
  • AMBP1 3
  • ARMD4 3
  • ARMS1 3
  • CFHL3 3
  • FHL1 3
  • HUS 3
  • FH 3

External Ids for CFH Gene

Previous HGNC Symbols for CFH Gene

  • HF
  • HF1
  • HF2

Previous GeneCards Identifiers for CFH Gene

  • GC01P193352
  • GC01P194887
  • GC01P167862

Summaries for CFH Gene

Entrez Gene Summary for CFH Gene

  • This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]

GeneCards Summary for CFH Gene

CFH (Complement Factor H) is a Protein Coding gene. Diseases associated with CFH include Complement Factor H Deficiency and Hemolytic Uremic Syndrome, Atypical 1. Among its related pathways are Creation of C4 and C2 activators and Complement and coagulation cascades. Gene Ontology (GO) annotations related to this gene include heparin binding and heparan sulfate proteoglycan binding. An important paralog of this gene is CFHR5.

UniProtKB/Swiss-Prot for CFH Gene

  • Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway.

Gene Wiki entry for CFH Gene

Additional gene information for CFH Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFH Gene

Genomics for CFH Gene

GeneHancer (GH) Regulatory Elements for CFH Gene

Promoters and enhancers for CFH Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I196649 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +0.1 144 4.4 HDAC1 MEIS2 FOXA2 PKNOX1 ATF1 TAF1 TAF9B GTF2E2 E4F1 RAD21 CFH CFHR1 CFHR3 GC01M196672
GH01I196410 Enhancer 0.2 FANTOM5 1.3 -241.3 -241265 0.5 KCNT2 CFHR3 CFH GC01M196344 GC01P196522
GH01I196660 Enhancer 0.6 Ensembl 0.4 +9.1 9123 0.4 CTCF ZNF654 REST ELF1 RAD21 ARID2 VEZF1 SMC3 ZNF143 PRDM1 KCNT2 CFH GC01M196672
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CFH on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CFH gene promoter:

Genomic Locations for CFH Gene

Genomic Locations for CFH Gene
95,627 bases
Plus strand

Genomic View for CFH Gene

Genes around CFH on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CFH Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CFH Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFH Gene

Proteins for CFH Gene

  • Protein details for CFH Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Complement factor H
    Protein Accession:
    Secondary Accessions:
    • A5PL14
    • P78435
    • Q14570
    • Q2TAZ5
    • Q38G77
    • Q5TFM3
    • Q8N708
    • Q9NU86

    Protein attributes for CFH Gene

    1231 amino acids
    Molecular mass:
    139096 Da
    Quaternary structure:
    • (Microbial infection) Interacts with West nile virus non-structural protein 1 (NS1); this interaction leads to the degradation of C3.
    • Sequence=CAB41739.1; Type=Frameshift; Positions=341; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for CFH Gene

    Alternative splice isoforms for CFH Gene


neXtProt entry for CFH Gene

Post-translational modifications for CFH Gene

  • Glycosylation at Asn217, Asn529, Asn718, Asn802, Asn822, posLast=882882, posLast=911911, Asn1029, and posLast=10951095
  • Modification sites at PhosphoSitePlus

Other Protein References for CFH Gene

No data available for DME Specific Peptides for CFH Gene

Domains & Families for CFH Gene

Gene Families for CFH Gene

Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Plasma proteins
  • Predicted secreted proteins

Protein Domains for CFH Gene

Suggested Antigen Peptide Sequences for CFH Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CFH: view

No data available for UniProtKB/Swiss-Prot for CFH Gene

Function for CFH Gene

Molecular function for CFH Gene

UniProtKB/Swiss-Prot Function:
Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway.

Phenotypes From GWAS Catalog for CFH Gene

Gene Ontology (GO) - Molecular Function for CFH Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16612335
GO:0008201 heparin binding IDA 22471560
GO:0043395 heparan sulfate proteoglycan binding IDA 22471560
genes like me logo Genes that share ontologies with CFH: view
genes like me logo Genes that share phenotypes with CFH: view

Human Phenotype Ontology for CFH Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for CFH Gene

MGI Knock Outs for CFH:
  • Cfh tm1Mbo
  • Cfh tm1a(EUCOMM)Wtsi

miRNA for CFH Gene

miRTarBase miRNAs that target CFH

Clone Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for CFH Gene

Localization for CFH Gene

Subcellular locations from UniProtKB/Swiss-Prot for CFH Gene


Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CFH gene
Compartment Confidence
extracellular 5
plasma membrane 3
mitochondrion 1
nucleus 1
endoplasmic reticulum 1
cytosol 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for CFH Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space TAS 9312129
GO:0070062 extracellular exosome IDA,HDA 23533145
GO:0072562 blood microparticle HDA,IDA 22516433
genes like me logo Genes that share ontologies with CFH: view

Pathways & Interactions for CFH Gene

genes like me logo Genes that share pathways with CFH: view

Pathways by source for CFH Gene

1 Sino Biological pathway for CFH Gene
1 BioSystems pathway for CFH Gene
1 GeneGo (Thomson Reuters) pathway for CFH Gene

Gene Ontology (GO) - Biological Process for CFH Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006956 complement activation IDA 24835392
GO:0006957 complement activation, alternative pathway IEA --
GO:0016032 viral process IEA --
GO:0030449 regulation of complement activation TAS --
GO:0045087 innate immune response IEA --
genes like me logo Genes that share ontologies with CFH: view

No data available for SIGNOR curated interactions for CFH Gene

Drugs & Compounds for CFH Gene

(20) Drugs for CFH Gene - From: DrugBank, PharmGKB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Zinc Approved, Investigational Pharma Target 2430
Copper Approved, Investigational Pharma Target 202
Bevacizumab Approved, Investigational Pharma VEGF antagonist, Therapeutic Antibodies, Vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) inhibitors 2087
Ranibizumab Approved Pharma 502
photodynamic therapy Pharma 0

(7) Additional Compounds for CFH Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with CFH: view

Transcripts for CFH Gene

Unigene Clusters for CFH Gene

Complement factor H:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CFH Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
SP1: -
SP2: - -
SP3: - - -

Relevant External Links for CFH Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CFH Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CFH Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CFH Gene

This gene is overexpressed in Liver (x13.1) and Heart - Atrial Appendage (x4.8).

Protein differential expression in normal tissues from HIPED for CFH Gene

This gene is overexpressed in Serum (15.5), Plasma (15.3), Synovial fluid (14.8), and Monocytes (9.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CFH Gene

Protein tissue co-expression partners for CFH Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CFH Gene:


SOURCE GeneReport for Unigene cluster for CFH Gene:


mRNA Expression by UniProt/SwissProt for CFH Gene:

Tissue specificity: Expressed by the liver and secreted in plasma.

Evidence on tissue expression from TISSUES for CFH Gene

  • Liver(4.9)
  • Nervous system(4.7)
  • Bone marrow(4.2)
  • Heart(2.9)
  • Kidney(2.9)
  • Blood(2.8)
  • Eye(2.8)
  • Lung(2.4)
  • Intestine(2.2)
  • Skin(2.2)
  • Gall bladder(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for CFH Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
  • cardiovascular
  • digestive
  • immune
  • integumentary
  • nervous
  • respiratory
  • urinary
Head and neck:
  • brain
  • cranial nerve
  • ear
  • eye
  • head
  • heart
  • lung
  • duodenum
  • intestine
  • kidney
  • large intestine
  • liver
  • pancreas
  • small intestine
  • urinary bladder
  • blood
  • blood vessel
  • coagulation system
  • peripheral nerve
  • peripheral nervous system
  • red blood cell
  • skin
  • spinal cord
  • white blood cell
genes like me logo Genes that share expression patterns with CFH: view

Orthologs for CFH Gene

This gene was present in the common ancestor of animals.

Orthologs for CFH Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CFH 34 33
  • 98.62 (n)
(Canis familiaris)
Mammalia LOC478952 33
  • 75.55 (n)
-- 34
  • 59 (a)
-- 34
  • 59 (a)
(Bos Taurus)
Mammalia CFH 34 33
  • 75.2 (n)
-- 34
  • 62 (a)
-- 34
  • 60 (a)
-- 34
  • 55 (a)
(Rattus norvegicus)
Mammalia Cfh 33
  • 73.32 (n)
(Mus musculus)
Mammalia Cfh 33 16 34
  • 72.46 (n)
Cfhr3 34
  • 69 (a)
Gm4788 34
  • 57 (a)
Cfhr2 34
  • 55 (a)
Cfhr1 34
  • 47 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 47 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 26 (a)
(Gallus gallus)
Aves CFH 33
  • 54.61 (n)
-- 34
  • 34 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 36 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101731666 33
  • 48.21 (n)
(Danio rerio)
Actinopterygii LOC100535929 33
  • 49.05 (n)
cfhl3 34
  • 28 (a)
(Caenorhabditis elegans)
Secernentea F36H2.5 33
  • 42.28 (n)
Species where no ortholog for CFH was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CFH Gene

Gene Tree for CFH (if available)
Gene Tree for CFH (if available)

Paralogs for CFH Gene

(6) SIMAP similar genes for CFH Gene using alignment to 4 proteins: Pseudogenes for CFH Gene

genes like me logo Genes that share paralogs with CFH: view

Variants for CFH Gene

Sequence variations from dbSNP and Humsavar for CFH Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1061147 benign, Macular degeneration, Basal laminar drusen, Mesangiocapillary glomerulonephritis, type II, Atypical hemolytic uremic syndrome 196,685,194(+) A/C coding_sequence_variant, non_coding_transcript_variant, synonymous_variant
rs1061170 risk-factor, pathogenic, benign, Age-related macular degeneration 4, Basal laminar drusen, Macular degeneration, Mesangiocapillary glomerulonephritis, type II, Atypical hemolytic uremic syndrome 196,690,107(+) C/T coding_sequence_variant, missense_variant, non_coding_transcript_variant
rs1065489 benign, Basal laminar drusen, Macular degeneration, Mesangiocapillary glomerulonephritis, type II, Atypical hemolytic uremic syndrome 196,740,644(+) G/T coding_sequence_variant, genic_downstream_transcript_variant, missense_variant, non_coding_transcript_variant
rs121913051 risk-factor, uncertain-significance, Atypical hemolytic-uremic syndrome 1, CFH-Related Disorders 196,747,260(+) C/G/T coding_sequence_variant, genic_downstream_transcript_variant, missense_variant, non_coding_transcript_variant, stop_gained
rs121913052 pathogenic, Factor H deficiency 196,715,679(+) T/C coding_sequence_variant, genic_downstream_transcript_variant, missense_variant, non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CFH Gene

Variant ID Type Subtype PubMed ID
dgv132e212 CNV loss 25503493
dgv133e212 CNV loss 25503493
dgv42e201 CNV deletion 23290073
dgv503n100 CNV gain 25217958
dgv504n100 CNV gain 25217958
dgv505n100 CNV gain 25217958
dgv506n100 CNV gain 25217958
dgv507n100 CNV loss 25217958
dgv508n100 CNV loss 25217958
dgv509n100 CNV gain+loss 25217958
dgv510n100 CNV gain+loss 25217958
dgv511n100 CNV gain 25217958
dgv512n100 CNV loss 25217958
dgv733n54 CNV loss 21841781
dgv734n54 CNV loss 21841781
dgv735n54 CNV loss 21841781
dgv736n54 CNV loss 21841781
dgv86e199 CNV deletion 23128226
esv1001500 CNV deletion 20482838
esv1247490 CNV insertion 17803354
esv26552 CNV gain+loss 19812545
esv2758990 CNV gain+loss 17122850
esv3578358 CNV loss 25503493
esv3584613 CNV loss 24956385
esv3588467 CNV loss 21293372
esv3588468 CNV loss 21293372
esv3891026 CNV gain+loss 25118596
nsv1003733 CNV gain+loss 25217958
nsv1010268 CNV gain 25217958
nsv1159821 CNV deletion 26073780
nsv428290 CNV gain+loss 18775914
nsv469810 CNV loss 16826518
nsv471393 CNV gain 19718026
nsv471614 CNV gain+loss 15918152
nsv477921 CNV novel sequence insertion 20440878
nsv517662 CNV gain+loss 19592680
nsv528460 CNV gain 19592680
nsv548743 CNV loss 21841781
nsv548744 CNV loss 21841781
nsv548745 CNV gain 21841781
nsv548746 CNV loss 21841781
nsv548747 CNV gain 21841781
nsv548748 CNV gain 21841781
nsv548749 CNV loss 21841781
nsv548754 CNV loss 21841781
nsv548755 CNV loss 21841781
nsv818733 CNV gain 17921354
nsv818744 CNV gain 17921354
nsv819563 CNV gain 19587683
nsv825997 CNV loss 20364138
nsv826008 CNV loss 20364138
nsv8691 CNV gain+loss 18304495
nsv946555 CNV duplication 23825009

Variation tolerance for CFH Gene

Residual Variation Intolerance Score: 39% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.10; 75.45% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CFH Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CFH Gene

Disorders for CFH Gene

MalaCards: The human disease database

(40) MalaCards diseases for CFH Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
complement factor h deficiency
  • cfhd
hemolytic uremic syndrome, atypical 1
  • hemolytic uremic syndrome, atypical, susceptibility to, 1
basal laminar drusen
  • drusen of bruch membrane
macular degeneration, age-related, 4
  • armd4
atypical hemolytic-uremic syndrome with h factor anomaly
  • atypical hus with h factor anomaly
- elite association - COSMIC cancer census association via MalaCards
Search CFH in MalaCards View complete list of genes associated with diseases


  • Basal laminar drusen (BLD) [MIM:126700]: Drusen are extracellular deposits that accumulate below the retinal pigment epithelium on Bruch membrane. Basal laminar drusen refers to an early adult-onset drusen phenotype that shows a pattern of uniform small, slightly raised yellow subretinal nodules randomly scattered in the macula. In later stages, these drusen often become more numerous, with clustered groups of drusen scattered throughout the retina. In time these small basal laminar drusen may expand and ultimately lead to a serous pigment epithelial detachment of the macula that may result in vision loss. {ECO:0000269 PubMed:18252232}. Note=The gene represented in this entry is involved in disease pathogenesis.
  • Complement factor H deficiency (CFHD) [MIM:609814]: A disorder that can manifest as several different phenotypes, including asymptomatic, recurrent bacterial infections, and renal failure. Laboratory features usually include decreased serum levels of factor H, complement component C3, and a decrease in other terminal complement components, indicating activation of the alternative complement pathway. It is associated with a number of renal diseases with variable clinical presentation and progression, including membranoproliferative glomerulonephritis and atypical hemolytic uremic syndrome. {ECO:0000269 PubMed:10803850, ECO:0000269 PubMed:11158219, ECO:0000269 PubMed:11170895, ECO:0000269 PubMed:11170896, ECO:0000269 PubMed:12020532, ECO:0000269 PubMed:14978182, ECO:0000269 PubMed:16612335, ECO:0000269 PubMed:9312129}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Hemolytic uremic syndrome atypical 1 (AHUS1) [MIM:235400]: An atypical form of hemolytic uremic syndrome. It is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease. {ECO:0000269 PubMed:10577907, ECO:0000269 PubMed:10762557, ECO:0000269 PubMed:11851332, ECO:0000269 PubMed:12960213, ECO:0000269 PubMed:14583443, ECO:0000269 PubMed:14978182, ECO:0000269 PubMed:20513133, ECO:0000269 PubMed:9551389}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. Other genes may play a role in modifying the phenotype.
  • Macular degeneration, age-related, 4 (ARMD4) [MIM:610698]: A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. {ECO:0000269 PubMed:22019782}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Additional Disease Information for CFH

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with CFH: view

No data available for Genatlas for CFH Gene

Publications for CFH Gene

  1. Complement factor H polymorphism in age-related macular degeneration. (PMID: 15761122) Klein RJ … Hoh J (Science (New York, N.Y.) 2005) 3 4 22 44 58
  2. Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: the C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease. (PMID: 14583443) Caprioli J … International Registry of Recurrent and Familial HUS/TTP (Human molecular genetics 2003) 3 4 22 44 58
  3. Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome. (PMID: 10577907) Ying L … Landau D (American journal of human genetics 1999) 3 4 22 44 58
  4. Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome. (PMID: 20513133) Maga TK … Smith RJ (Human mutation 2010) 3 4 44 58
  5. The dot-and-fleck retinopathy of X linked Alport syndrome is independent of complement factor H (CFH) gene polymorphisms. (PMID: 19019939) Liu J … Savige J (The British journal of ophthalmology 2009) 3 22 44 58

Products for CFH Gene

Sources for CFH Gene

Loading form....