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Aliases for CFAP99 Gene

Aliases for CFAP99 Gene

  • Cilia And Flagella Associated Protein 99 2 3 5
  • Cilia- And Flagella-Associated Protein 99 3

External Ids for CFAP99 Gene

Summaries for CFAP99 Gene

GeneCards Summary for CFAP99 Gene

CFAP99 (Cilia And Flagella Associated Protein 99) is a Protein Coding gene.

Additional gene information for CFAP99 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP99 Gene

Genomics for CFAP99 Gene

GeneHancer (GH) Regulatory Elements for CFAP99 Gene

Promoters and enhancers for CFAP99 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J002415 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 650.7 -0.9 -893 4.2 PKNOX1 ARNT ARID4B SIN3A ZNF2 YY1 ZNF766 ZNF207 ZNF143 SP3 ZFYVE28 CFAP99 RNF4 HAUS3 NELFA ENSG00000270195 FAM193A SH3BP2 MXD4 GC04M002409
GH04J002361 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE 11.7 -55.4 -55442 4.5 FOXA2 PKNOX1 ATF1 YY1 RXRA REST ZNF592 NFIL3 GMEB1 SMARCA4 ZFYVE28 ENSG00000251148 MXD4 CFAP99 RNF4 LOC105374353 HAUS3 POLN NELFA C4orf48
GH04J002383 Enhancer 0.7 FANTOM5 dbSUPER 14.3 -35.0 -34952 0.2 GLIS1 GTF2A2 ZNF395 PIR52561 CFAP99 ZFYVE28 ENSG00000251148 MXD4 HAUS3 POLN SH3BP2 ENSG00000250623 TNIP2
GH04J002382 Enhancer 0.7 FANTOM5 14.3 -36.0 -35954 0.3 HDAC1 GTF2F1 CDC5L E4F1 FOSL1 POLR2B ZNF766 POLR2A FOXK2 EGR1 ZFYVE28 CFAP99 ENSG00000251148 MXD4 HAUS3 POLN ENSG00000250623 SH3BP2 TNIP2 PIR52561
GH04J002792 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 3.8 +381.4 381425 15.2 HDGF PKNOX1 CLOCK MLX ZFP64 ARID4B SIN3A DMAP1 ZBTB7B YY1 SH3BP2 ADD1 TNIP2 NOP14-AS1 GRK4 CFAP99 ZFYVE28 HTT
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CFAP99 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CFAP99 Gene

Genomic Locations for CFAP99 Gene
chr4:2,418,893-2,462,963
(GRCh38/hg38)
Size:
44,071 bases
Orientation:
Plus strand
chr4:2,420,701-2,464,690
(GRCh37/hg19)
Size:
43,990 bases
Orientation:
Plus strand

Genomic View for CFAP99 Gene

Genes around CFAP99 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CFAP99 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CFAP99 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFAP99 Gene

Proteins for CFAP99 Gene

  • Protein details for CFAP99 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    D6REC4-CFA99_HUMAN
    Recommended name:
    Cilia- and flagella-associated protein 99
    Protein Accession:
    D6REC4

    Protein attributes for CFAP99 Gene

    Size:
    459 amino acids
    Molecular mass:
    52293 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CFAP99 Gene

Post-translational modifications for CFAP99 Gene

No Post-translational modifications

Other Protein References for CFAP99 Gene

No data available for DME Specific Peptides for CFAP99 Gene

Domains & Families for CFAP99 Gene

Gene Families for CFAP99 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CFAP99 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

D6REC4

UniProtKB/Swiss-Prot:

CFA99_HUMAN :
  • Belongs to the CFAP99 family.
Family:
  • Belongs to the CFAP99 family.
genes like me logo Genes that share domains with CFAP99: view

No data available for Suggested Antigen Peptide Sequences for CFAP99 Gene

Function for CFAP99 Gene

Phenotypes From GWAS Catalog for CFAP99 Gene

genes like me logo Genes that share phenotypes with CFAP99: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CFAP99

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CFAP99 Gene

Localization for CFAP99 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CFAP99 Gene

Cell projection, cilium, flagellum.

Gene Ontology (GO) - Cellular Components for CFAP99 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0031514 motile cilium IEA --
genes like me logo Genes that share ontologies with CFAP99: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for CFAP99 Gene

Pathways & Interactions for CFAP99 Gene

SuperPathways for CFAP99 Gene

No Data Available

Interacting Proteins for CFAP99 Gene

Gene Ontology (GO) - Biological Process for CFAP99 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CFAP99 Gene

Drugs & Compounds for CFAP99 Gene

No Compound Related Data Available

Transcripts for CFAP99 Gene

mRNA/cDNA for CFAP99 Gene

(2) REFSEQ mRNAs :
(10) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CFAP99

Alternative Splicing Database (ASD) splice patterns (SP) for CFAP99 Gene

No ASD Table

Relevant External Links for CFAP99 Gene

GeneLoc Exon Structure for
CFAP99
ECgene alternative splicing isoforms for
CFAP99

Expression for CFAP99 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CFAP99 Gene

Protein differential expression in normal tissues from HIPED for CFAP99 Gene

This gene is overexpressed in Fetal Brain (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CFAP99 Gene



Protein tissue co-expression partners for CFAP99 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CFAP99 Gene:

CFAP99
genes like me logo Genes that share expression patterns with CFAP99: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CFAP99 Gene

Orthologs for CFAP99 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CFAP99 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC750504 33
  • 99.07 (n)
cow
(Bos Taurus)
Mammalia LOC100847979 33
  • 80.46 (n)
rat
(Rattus norvegicus)
Mammalia RGD1564567 33
  • 78.95 (n)
mouse
(Mus musculus)
Mammalia Gm21446 33
  • 78.69 (n)
Cfap99 16
chicken
(Gallus gallus)
Aves LOC422887 33
  • 56.72 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100495334 33
  • 56.25 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC100534701 33
  • 51.78 (n)
Species where no ortholog for CFAP99 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CFAP99 Gene

ENSEMBL:
Gene Tree for CFAP99 (if available)
TreeFam:
Gene Tree for CFAP99 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CFAP99: view image

Paralogs for CFAP99 Gene

No data available for Paralogs for CFAP99 Gene

Variants for CFAP99 Gene

Sequence variations from dbSNP and Humsavar for CFAP99 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1000011008 -- 2,419,669(+) G/C intron_variant
rs1000059398 -- 2,462,413(+) T/G intron_variant
rs1000064899 -- 2,442,481(+) G/C intron_variant
rs1000081716 -- 2,429,691(+) A/G intron_variant
rs1000111453 -- 2,462,198(+) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CFAP99 Gene

Variant ID Type Subtype PubMed ID
dgv806e201 CNV deletion 23290073
dgv807e201 CNV deletion 23290073
esv1499184 CNV deletion 17803354
esv25676 CNV loss 19812545
esv2662736 CNV deletion 23128226
esv2726835 CNV deletion 23290073
esv2726846 CNV deletion 23290073
esv2726852 CNV deletion 23290073
esv275562 CNV gain+loss 21479260
esv32578 CNV loss 17666407
esv3336658 CNV duplication 20981092
esv3599402 CNV loss 21293372
esv8335 CNV gain 19470904
nsv1009347 CNV gain 25217958
nsv1010352 CNV gain 25217958
nsv1013194 CNV gain 25217958
nsv289764 CNV deletion 16902084
nsv292996 CNV deletion 16902084
nsv293699 CNV insertion 16902084
nsv518472 CNV loss 19592680
nsv593403 CNV loss 21841781
nsv593419 CNV loss 21841781

Additional Variant Information for CFAP99 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CFAP99

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CFAP99 Gene

Disorders for CFAP99 Gene

Additional Disease Information for CFAP99

No disorders were found for CFAP99 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CFAP99 Gene

Publications for CFAP99 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for CFAP99 Gene

Sources for CFAP99 Gene

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