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Aliases for CFAP97D1 Gene

Aliases for CFAP97D1 Gene

  • CFAP97 Domain Containing 1 2 3
  • C17orf105 3 4 5
  • Chromosome 17 Open Reading Frame 105 2 5
  • Uncharacterized Protein C17orf105 3

External Ids for CFAP97D1 Gene

Previous HGNC Symbols for CFAP97D1 Gene

  • C17orf105

Summaries for CFAP97D1 Gene

GeneCards Summary for CFAP97D1 Gene

CFAP97D1 (CFAP97 Domain Containing 1) is a Protein Coding gene.

Additional gene information for CFAP97D1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP97D1 Gene

Genomics for CFAP97D1 Gene

GeneHancer (GH) Regulatory Elements for CFAP97D1 Gene

Promoters and enhancers for CFAP97D1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I043777 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +0.3 265 2.7 HDGF PKNOX1 MLX ARNT ARID4B NEUROD1 SIN3A FEZF1 DMAP1 YY1 DUSP3 CFAP97D1 PIR48941 ASB16-AS1 UBTF HMGN1P29 TMUB2 DHX8 ENSG00000267340 LINC00910
GH17I043780 Promoter 0.5 EPDnew 550.8 +2.0 2025 0.1 CFAP97D1 PIR48941 DUSP3
GH17I043926 Enhancer 1.1 FANTOM5 Ensembl ENCODE 23.8 +149.8 149817 2.8 SOX5 SOX13 GATAD2A TFAP4 HMG20A SKI TCF7 PRDM10 SMAD4 ZBTB12 LOC105371788 LRRC37A10P LOC102724183 LSM12 CFAP97D1 MPP2 NAGS PYY ENSG00000221044 CD300LG
GH17I043839 Enhancer 1 Ensembl ENCODE 10.9 +61.8 61755 1.6 NFIB RAD21 YY1 ZNF335 ZNF366 SCRT2 RCOR1 ZNF391 ELK4 SMARCC1 DUSP3 CFAP97D1 MPP2 MPP3 MEOX1 CD300LG
GH17I044024 Enhancer 0.4 FANTOM5 25.2 +246.1 246073 0.4 KLF9 RCOR1 TMEM101 PYY ENSG00000221044 CFAP97D1 LSM12 NAGS CD300LG GC17P043983
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CFAP97D1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CFAP97D1 Gene

Genomic Locations for CFAP97D1 Gene
chr17:43,778,391-43,787,612
(GRCh38/hg38)
Size:
9,222 bases
Orientation:
Plus strand
chr17:41,857,803-41,864,980
(GRCh37/hg19)

Genomic View for CFAP97D1 Gene

Genes around CFAP97D1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CFAP97D1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CFAP97D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFAP97D1 Gene

Proteins for CFAP97D1 Gene

  • Protein details for CFAP97D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B2RV13-CQ105_HUMAN
    Recommended name:
    Uncharacterized protein C17orf105
    Protein Accession:
    B2RV13

    Protein attributes for CFAP97D1 Gene

    Size:
    164 amino acids
    Molecular mass:
    19546 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CFAP97D1 Gene

Post-translational modifications for CFAP97D1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CFAP97D1 Gene

No data available for DME Specific Peptides for CFAP97D1 Gene

Domains & Families for CFAP97D1 Gene

Gene Families for CFAP97D1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CFAP97D1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CFAP97D1: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CFAP97D1 Gene

Function for CFAP97D1 Gene

Phenotypes From GWAS Catalog for CFAP97D1 Gene

miRNA for CFAP97D1 Gene

miRTarBase miRNAs that target CFAP97D1

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CFAP97D1 Gene

Localization for CFAP97D1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CFAP97D1 gene
Compartment Confidence
nucleus 2
cytosol 2
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CFAP97D1 Gene

Pathways & Interactions for CFAP97D1 Gene

SuperPathways for CFAP97D1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CFAP97D1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CFAP97D1 Gene

Drugs & Compounds for CFAP97D1 Gene

No Compound Related Data Available

Transcripts for CFAP97D1 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CFAP97D1 Gene

No ASD Table

Relevant External Links for CFAP97D1 Gene

GeneLoc Exon Structure for
CFAP97D1
ECgene alternative splicing isoforms for
CFAP97D1

Expression for CFAP97D1 Gene

NURSA nuclear receptor signaling pathways regulating expression of CFAP97D1 Gene:

CFAP97D1

Evidence on tissue expression from TISSUES for CFAP97D1 Gene

  • Blood(2)
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CFAP97D1 Gene

Orthologs for CFAP97D1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CFAP97D1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf105 33
  • 99.19 (n)
C17orf105 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C9H17orf105 33
  • 91.67 (n)
C17orf105 34
  • 90 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C19H17orf105 33
  • 90.45 (n)
C17orf105 34
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700006E09Rik 33 16 34
  • 87.8 (n)
rat
(Rattus norvegicus)
Mammalia RGD1565533 33
  • 86.59 (n)
oppossum
(Monodelphis domestica)
Mammalia C17orf105 34
  • 48 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C17orf105 34
  • 29 (a)
OneToOne
chicken
(Gallus gallus)
Aves C17orf105 34
  • 35 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C17orf105 34
  • 40 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii C25H17orf105 (1 of 2) 34
  • 23 (a)
OneToMany
C9H17orf105 (2 of 2) 34
  • 22 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 27 (a)
OneToOne
Species where no ortholog for CFAP97D1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CFAP97D1 Gene

ENSEMBL:
Gene Tree for CFAP97D1 (if available)
TreeFam:
Gene Tree for CFAP97D1 (if available)

Paralogs for CFAP97D1 Gene

No data available for Paralogs for CFAP97D1 Gene

Variants for CFAP97D1 Gene

Sequence variations from dbSNP and Humsavar for CFAP97D1 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000602014 -- 43,778,777(+) C/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000972813 -- 43,778,936(+) G/A genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1001088813 -- 43,779,011(+) G/C genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1001236686 -- 43,778,873(+) C/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1001251253 -- 43,784,691(+) G/T 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant, non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CFAP97D1 Gene

Variant ID Type Subtype PubMed ID
esv27934 CNV gain 19812545
esv3640637 CNV gain 21293372
nsv1060861 CNV gain 25217958
nsv1146669 OTHER inversion 26484159

Variation tolerance for CFAP97D1 Gene

Gene Damage Index Score: 0.89; 18.61% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CFAP97D1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CFAP97D1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CFAP97D1 Gene

Disorders for CFAP97D1 Gene

Additional Disease Information for CFAP97D1

No disorders were found for CFAP97D1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CFAP97D1 Gene

Publications for CFAP97D1 Gene

  1. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for CFAP97D1 Gene

Sources for CFAP97D1 Gene

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