This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier syste... See more...

Aliases for CES3 Gene

Aliases for CES3 Gene

  • Carboxylesterase 3 2 3 4 5
  • Liver Carboxylesterase 31 Homolog 3 4
  • Carboxylesterase 3 (Brain) 2 3
  • Esterase 31 2 3
  • EC 3.1.1.1 4 50
  • ES31 2 3
  • Brain Carboxylesterase BR3 2
  • FLJ21736 2
  • EC 3.1.1 50
  • CES3 5

External Ids for CES3 Gene

Previous GeneCards Identifiers for CES3 Gene

  • GC16U990091
  • GC16P055532
  • GC16M055612
  • GC16M054394
  • GC16P065553
  • GC16P066995
  • GC16P052869

Summaries for CES3 Gene

Entrez Gene Summary for CES3 Gene

  • This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.[provided by RefSeq, Jun 2010]

GeneCards Summary for CES3 Gene

CES3 (Carboxylesterase 3) is a Protein Coding gene. Diseases associated with CES3 include Lymph Node Tuberculosis and Cholesterol Ester Storage Disease. Among its related pathways are Cytochrome P450 - arranged by substrate type and Metabolism. Gene Ontology (GO) annotations related to this gene include hydrolase activity and carboxylic ester hydrolase activity. An important paralog of this gene is CES2.

UniProtKB/Swiss-Prot Summary for CES3 Gene

  • Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.

Gene Wiki entry for CES3 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CES3 Gene

Genomics for CES3 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CES3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J066960 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE 250.7 0.0 -35 1.2 ZNF600 POLR2A REST DEK TRIM22 HOMEZ CTCF SIN3A ARNT KMT2B CES3 FBXL8 TRADD HSF4 CES2 RRAD CDH16 CIAO2B B3GNT9 CBFB
GH16J066948 Promoter/Enhancer 1.3 EPDnew ENCODE dbSUPER 261.9 -13.0 -12978 1.5 SSRP1 CHD4 SIN3A TRIM22 CHD2 KMT2B THAP11 RXRA SAP130 TEAD3 CES3 HSALNG0112139 ENSG00000265408 HSALNG0112138 LOC107984881 CES2
GH16J066932 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 11.9 -25.9 -25944 5 SP1 MYC ZNF600 IKZF1 SSRP1 ZNF580 ZNF592 KLF9 CEBPA POLR2A CES2 CIAO2B CES3 NAE1 ENSG00000265408 lnc-FAM96B-3
GH16J066879 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 9.4 -80.5 -80544 2.6 SP1 NCOR1 IKZF1 MYC SSRP1 ZNF580 ZNF592 KLF9 CEBPA ZNF10 PDP2 lnc-PDP2-3 CES2 B3GNT9 CTCF ENSG00000260465 CDH16 RRAD NAE1 ZDHHC1
GH16J066902 Enhancer 1.8 VISTA FANTOM5 ENCODE CraniofacialAtlas dbSUPER 9.5 -56.7 -56704 4.1 IKZF1 SSRP1 ZMYM3 CEBPA ZNF10 ZIC2 NFIC CHD4 KLF11 ZNF341 HSALNG0112130 LOC107984821 lnc-CDH16-1 CES2 KIAA0895L E2F4 NAE1 RRAD CIAO2B EDC4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CES3 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CES3

Top Transcription factor binding sites by QIAGEN in the CES3 gene promoter:
  • AML1a
  • C/EBPalpha
  • GR
  • GR-alpha
  • HEN1
  • NF-kappaB1
  • Pax-3

Genomic Locations for CES3 Gene

Latest Assembly
chr16:66,961,245-66,975,149
(GRCh38/hg38)
Size:
13,905 bases
Orientation:
Plus strand

Previous Assembly
chr16:66,995,169-67,009,052
(GRCh37/hg19 by Entrez Gene)
Size:
13,884 bases
Orientation:
Plus strand

chr16:66,995,140-67,009,051
(GRCh37/hg19 by Ensembl)
Size:
13,912 bases
Orientation:
Plus strand

Genomic View for CES3 Gene

Genes around CES3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CES3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CES3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CES3 Gene

Proteins for CES3 Gene

  • Protein details for CES3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UWW8-EST3_HUMAN
    Recommended name:
    Carboxylesterase 3
    Protein Accession:
    Q6UWW8
    Secondary Accessions:
    • B2Z3W9
    • F5H242
    • Q7Z6J1
    • Q9H6X7

    Protein attributes for CES3 Gene

    Size:
    571 amino acids
    Molecular mass:
    62282 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CES3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CES3 Gene

Selected DME Specific Peptides for CES3 Gene

Q6UWW8:
  • GFFSTGD
  • FLGIPFA
  • FARTGDPN
  • AALRWVQ
  • YRLGVLGF

Post-translational modifications for CES3 Gene

Other Protein References for CES3 Gene

Domains & Families for CES3 Gene

Gene Families for CES3 Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins

Protein Domains for CES3 Gene

Suggested Antigen Peptide Sequences for CES3 Gene

GenScript: Design optimal peptide antigens:
  • Liver carboxylesterase 31 homolog (EST3_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6UWW8

UniProtKB/Swiss-Prot:

EST3_HUMAN :
  • Belongs to the type-B carboxylesterase/lipase family.
Family:
  • Belongs to the type-B carboxylesterase/lipase family.
genes like me logo Genes that share domains with CES3: view

Function for CES3 Gene

Molecular function for CES3 Gene

UniProtKB/Swiss-Prot Function:
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+); Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1; Evidence={ECO:0000255|PROSITE-ProRule:PRU10039};.
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=137 uM for 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin {ECO:0000269|PubMed:15100172}; KM=460 uM for 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin {ECO:0000269|PubMed:15100172};

Enzyme Numbers (IUBMB) for CES3 Gene

Phenotypes From GWAS Catalog for CES3 Gene

Gene Ontology (GO) - Molecular Function for CES3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004771 sterol esterase activity IBA 21873635
GO:0004806 triglyceride lipase activity IBA 21873635
GO:0016787 hydrolase activity IEA --
GO:0052689 carboxylic ester hydrolase activity TAS --
GO:0080030 methyl indole-3-acetate esterase activity IEA --
genes like me logo Genes that share ontologies with CES3: view
genes like me logo Genes that share phenotypes with CES3: view

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CES3

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CES3 Gene

Localization for CES3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CES3 Gene

Endoplasmic reticulum lumen.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CES3 gene
Compartment Confidence
extracellular 5
endoplasmic reticulum 4
cytosol 4
lysosome 2
plasma membrane 1
cytoskeleton 1
mitochondrion 1
peroxisome 1
nucleus 1
endosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (2)
  • Nuclear membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CES3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IBA 21873635
GO:0005783 endoplasmic reticulum IEA --
GO:0005788 endoplasmic reticulum lumen IEA --
GO:0005829 cytosol TAS --
GO:0070062 extracellular exosome HDA 19199708
genes like me logo Genes that share ontologies with CES3: view

Pathways & Interactions for CES3 Gene

genes like me logo Genes that share pathways with CES3: view

Gene Ontology (GO) - Biological Process for CES3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006805 xenobiotic metabolic process TAS --
GO:0016042 lipid catabolic process IBA 21873635
GO:0034383 low-density lipoprotein particle clearance TAS --
genes like me logo Genes that share ontologies with CES3: view

No data available for SIGNOR curated interactions for CES3 Gene

Drugs & Compounds for CES3 Gene

(6) Drugs for CES3 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Palmitic Acid Approved Pharma 27
Stearic acid Approved, Experimental Pharma 0
Water Approved Pharma 0
arachidonic acid Experimental Pharma 41
Myristic acid Experimental Pharma 0

(4) Additional Compounds for CES3 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Arachidic acid
  • Arachic acid
  • Arachidinic acid
  • Arachinsaeure
  • C20:0
  • CH3-[CH2]18-COOH
506-30-9
Heptadecanoic acid
  • 17:0
  • C17:0
  • CH3-[CH2]15-COOH
  • Heptadecoic acid
  • Heptadecylic acid
506-12-7
Heptadecanoyl CoA
  • Heptadecanoyl-coenzyme A
  • Heptadecanoate
  • Heptadecanoic acid
  • Heptadecanoic acid CoA
  • Heptadecanoyl coenzyme A
3546-17-6
Pentadecanoic acid
  • 15:00
  • C15
  • C15:0
  • N-Pentadecanoic acid
  • Pentadecylic acid
1002-84-2
genes like me logo Genes that share compounds with CES3: view

Transcripts for CES3 Gene

mRNA/cDNA for CES3 Gene

4 REFSEQ mRNAs :
8 NCBI additional mRNA sequence :
8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CES3

Alternative Splicing Database (ASD) splice patterns (SP) for CES3 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14a · 14b · 14c
SP1: - - -
SP2: - -
SP3: - - -
SP4: - - - -
SP5:
SP6:

Relevant External Links for CES3 Gene

GeneLoc Exon Structure for
CES3

Expression for CES3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CES3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CES3 Gene

This gene is overexpressed in Colon - Transverse (x15.5), Liver (x9.4), and Muscle - Skeletal (x6.0).

Protein differential expression in normal tissues from HIPED for CES3 Gene

This gene is overexpressed in Milk (24.2), Colon (14.8), Stomach (12.2), and Gallbladder (10.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CES3 Gene



Protein tissue co-expression partners for CES3 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CES3

SOURCE GeneReport for Unigene cluster for CES3 Gene:

Hs.268700

mRNA Expression by UniProt/SwissProt for CES3 Gene:

Q6UWW8-EST3_HUMAN
Tissue specificity: Expressed in liver, colon and small intestine.

Evidence on tissue expression from TISSUES for CES3 Gene

  • Liver(4.6)
  • Intestine(4.5)
  • Eye(4)
  • Kidney(2.2)
genes like me logo Genes that share expression patterns with CES3: view

Primer products for research

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CES3 Gene

Orthologs for CES3 Gene

This gene was present in the common ancestor of animals.

Orthologs for CES3 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia CES3 29 30
  • 98.89 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia CES3 29 30
  • 79.82 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Ces3b 29 16 30
  • 75.23 (n)
OneToMany
Ces3a 16 30
  • 65 (a)
OneToMany
Rat
(Rattus norvegicus)
Mammalia Ces3a 29
  • 74.05 (n)
Platypus
(Ornithorhynchus anatinus)
Mammalia CES3 30
  • 52 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia CES3 30
  • 51 (a)
OneToOne
Zebrafish
(Danio rerio)
Actinopterygii ces2 30
  • 41 (a)
ManyToMany
ces3 30
  • 41 (a)
ManyToMany
si:ch211-93f2.1 30
  • 14 (a)
ManyToMany
Fruit Fly
(Drosophila melanogaster)
Insecta CG8424 31
  • 42 (a)
alpha-Est4 31
  • 38 (a)
CG3841 31
  • 34 (a)
clt 31
  • 31 (a)
alpha-Est8 31
  • 31 (a)
BcDNA:GH05741 31
  • 30 (a)
CG6018 31
  • 30 (a)
alpha-Est2 31
  • 30 (a)
alpha-Est6 31
  • 30 (a)
alpha-Est7 31
  • 30 (a)
Jhe 31
  • 30 (a)
CG10175 31
  • 29 (a)
CG6414 31
  • 29 (a)
Est-P 31
  • 29 (a)
alpha-Est10 31
  • 29 (a)
CG4382 31
  • 28 (a)
CG5397 31
  • 28 (a)
alpha-Est3 31
  • 28 (a)
alpha-Est9 31
  • 28 (a)
Est-6 31
  • 27 (a)
CG9289 31
  • 27 (a)
CG10339 31
  • 26 (a)
CG7529 31
  • 26 (a)
Worm
(Caenorhabditis elegans)
Secernentea F15A8.6 31
  • 45 (a)
K11G9.1 31
  • 41 (a)
R173.3 31
  • 37 (a)
Y75B8A.3 31
  • 36 (a)
B0238.13 31
  • 33 (a)
B0238.1 31
  • 31 (a)
C52A10.1 31
  • 31 (a)
C52A10.2 31
  • 31 (a)
F13H6.3 31
  • 30 (a)
F07C4.12 31
  • 30 (a)
Y71H2AM.13 31
  • 30 (a)
T28C12.4a 31
  • 29 (a)
T28C12.4b 31
  • 29 (a)
B0238.7 31
  • 29 (a)
F13H6.4 31
  • 29 (a)
ges-1 31
  • 28 (a)
K07C11.4 31
  • 28 (a)
F55D10.3 31
  • 27 (a)
T02B5.3 31
  • 27 (a)
K11G9.2 31
  • 27 (a)
T02B5.1 31
  • 26 (a)
T07H6.1a 31
  • 26 (a)
ZC376.2 31
  • 24 (a)
Species where no ortholog for CES3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)

Evolution for CES3 Gene

ENSEMBL:
Gene Tree for CES3 (if available)
TreeFam:
Gene Tree for CES3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CES3: view image
Alliance of Genome Resources:
Additional Orthologs for CES3

Paralogs for CES3 Gene

Paralogs for CES3 Gene

(16) SIMAP similar genes for CES3 Gene using alignment to 3 proteins:

  • EST3_HUMAN
  • H3BRE5_HUMAN
  • H3BUA3_HUMAN
genes like me logo Genes that share paralogs with CES3: view

Variants for CES3 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CES3 Gene

SNP ID Clinical significance and condition Chr 16 pos Variation AA Info Type
rs61742964 -- p.Glu191Lys
rs61743167 -- p.Arg367Trp
rs61745806 -- p.Val129Ile
rs71647891 -- p.Ala151Thr
rs71647892 -- p.Tyr160His

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for CES3 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for CES3 Gene

Variant ID Type Subtype PubMed ID
dgv526e214 CNV gain 21293372
nsv827706 CNV loss 20364138

Variation tolerance for CES3 Gene

Residual Variation Intolerance Score: 93.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.28; 62.65% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CES3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CES3
Leiden Open Variation Database (LOVD)
CES3

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CES3 Gene

Disorders for CES3 Gene

MalaCards: The human disease database

(2) MalaCards diseases for CES3 Gene - From: COP

Disorder Aliases PubMed IDs
lymph node tuberculosis
  • king's evil
cholesterol ester storage disease
- elite association - COSMIC cancer census association via MalaCards
Search CES3 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for CES3

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with CES3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CES3 Gene

Publications for CES3 Gene

  1. Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3. (PMID: 15100172) Sanghani SP … Bosron WF (Drug metabolism and disposition: the biological fate of chemicals 2004) 2 3 4 22
  2. Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis. (PMID: 14581373) Sanghani SP … Bosron WF (Clinical cancer research : an official journal of the American Association for Cancer Research 2003) 2 3 4 22
  3. Mammalian carboxylesterase 3: comparative genomics and proteomics. (PMID: 20422440) Holmes RS … VandeBerg JL (Genetica 2010) 3 22
  4. Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins. (PMID: 20931200) Holmes RS … Maltais LJ (Mammalian genome : official journal of the International Mammalian Genome Society 2010) 2 3
  5. Human carboxylesterases: an update on CES1, CES2 and CES3. (PMID: 19508181) Sanghani SP … Bosron WF (Protein and peptide letters 2009) 3 22

Products for CES3 Gene

Sources for CES3 Gene