This gene codes for a choline/ethanolaminephosphotransferase, which functions in the synthesis of choline- or ethanolamine- containing phospholipids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016] See more...

Aliases for CEPT1 Gene

Aliases for CEPT1 Gene

  • Choline/Ethanolamine Phosphotransferase 1 2 3 5
  • Choline/Ethanolaminephosphotransferase 1 3 4
  • EC 4 51
  • EC 4
  • EC 2.7.8 51
  • HCEPT1 4
  • CEPT1 5

External Ids for CEPT1 Gene

Previous GeneCards Identifiers for CEPT1 Gene

  • GC01P112099
  • GC01P110554
  • GC01P110784
  • GC01P110981
  • GC01P111394
  • GC01P111682
  • GC01P109554

Summaries for CEPT1 Gene

Entrez Gene Summary for CEPT1 Gene

  • This gene codes for a choline/ethanolaminephosphotransferase, which functions in the synthesis of choline- or ethanolamine- containing phospholipids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

GeneCards Summary for CEPT1 Gene

CEPT1 (Choline/Ethanolamine Phosphotransferase 1) is a Protein Coding gene. Among its related pathways are Glycerophospholipid biosynthesis and Acyl chain remodelling of PE. Gene Ontology (GO) annotations related to this gene include phosphotransferase activity, for other substituted phosphate groups and ethanolaminephosphotransferase activity. An important paralog of this gene is CHPT1.

UniProtKB/Swiss-Prot Summary for CEPT1 Gene

  • Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity.

Additional gene information for CEPT1 Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CEPT1 Gene

Genomics for CEPT1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CEPT1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CEPT1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CEPT1

Top Transcription factor binding sites by QIAGEN in the CEPT1 gene promoter:
  • E2F
  • E2F-1
  • E2F-2
  • E2F-3a
  • E2F-5

Genomic Locations for CEPT1 Gene

Genomic Locations for CEPT1 Gene
45,722 bases
Plus strand
45,476 bases
Plus strand

Genomic View for CEPT1 Gene

Genes around CEPT1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CEPT1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CEPT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CEPT1 Gene

Proteins for CEPT1 Gene

  • Protein details for CEPT1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Choline/ethanolaminephosphotransferase 1
    Protein Accession:
    Secondary Accessions:
    • Q69YJ9
    • Q9P0Y8

    Protein attributes for CEPT1 Gene

    416 amino acids
    Molecular mass:
    46554 Da
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
    Quaternary structure:
    No Data Available
    • Sequence=AAF61194.1; Type=Frameshift; Evidence={ECO:0000305};

neXtProt entry for CEPT1 Gene

Selected DME Specific Peptides for CEPT1 Gene


Post-translational modifications for CEPT1 Gene

  • Glycosylation at Asn144
  • Modification sites at PhosphoSitePlus

Other Protein References for CEPT1 Gene

Domains & Families for CEPT1 Gene

Gene Families for CEPT1 Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Predicted membrane proteins
  • Transporters

Protein Domains for CEPT1 Gene

  • CDP-alcohol phosphatidyltransferase

Suggested Antigen Peptide Sequences for CEPT1 Gene

GenScript: Design optimal peptide antigens:
  • Choline/ethanolaminephosphotransferase 1 (CEPT1_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  • Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
genes like me logo Genes that share domains with CEPT1: view

Function for CEPT1 Gene

Molecular function for CEPT1 Gene

UniProtKB/Swiss-Prot Function:
Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a 1,2-diacyl-sn-glycerol + CDP-ethanolamine = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+); Xref=Rhea:RHEA:32943, ChEBI:CHEBI:15378, ChEBI:CHEBI:17815, ChEBI:CHEBI:57876, ChEBI:CHEBI:60377, ChEBI:CHEBI:64612; EC=; Evidence={ECO:0000269|PubMed:10191259};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a 1,2-diacyl-sn-glycerol + CDP-choline = a 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+); Xref=Rhea:RHEA:32939, ChEBI:CHEBI:15378, ChEBI:CHEBI:17815, ChEBI:CHEBI:57643, ChEBI:CHEBI:58779, ChEBI:CHEBI:60377; EC=; Evidence={ECO:0000269|PubMed:10191259};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+); Xref=Rhea:RHEA:54232, ChEBI:CHEBI:15378, ChEBI:CHEBI:58779, ChEBI:CHEBI:60377, ChEBI:CHEBI:76979, ChEBI:CHEBI:78228; Evidence={ECO:0000269|PubMed:10191259};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1,2-didecanoyl-sn-glycerol + CDP-choline = 1,2-didecanoyl-sn-glycero-3-phosphocholine + CMP + H(+); Xref=Rhea:RHEA:54236, ChEBI:CHEBI:15378, ChEBI:CHEBI:18155, ChEBI:CHEBI:58779, ChEBI:CHEBI:60377, ChEBI:CHEBI:78226; Evidence={ECO:0000269|PubMed:10191259};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-choline = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+); Xref=Rhea:RHEA:54240, ChEBI:CHEBI:15378, ChEBI:CHEBI:52333, ChEBI:CHEBI:58779, ChEBI:CHEBI:60377, ChEBI:CHEBI:74669; Evidence={ECO:0000269|PubMed:10191259};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-choline = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+); Xref=Rhea:RHEA:54244, ChEBI:CHEBI:15378, ChEBI:CHEBI:58779, ChEBI:CHEBI:60377, ChEBI:CHEBI:73001, ChEBI:CHEBI:75466; Evidence={ECO:0000269|PubMed:10191259};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+); Xref=Rhea:RHEA:54248, ChEBI:CHEBI:15378, ChEBI:CHEBI:52333, ChEBI:CHEBI:57876, ChEBI:CHEBI:60377, ChEBI:CHEBI:74986; Evidence={ECO:0000269|PubMed:10191259};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+); Xref=Rhea:RHEA:54252, ChEBI:CHEBI:15378, ChEBI:CHEBI:57876, ChEBI:CHEBI:60377, ChEBI:CHEBI:73007, ChEBI:CHEBI:75466; Evidence={ECO:0000269|PubMed:10191259};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + CDP-choline = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CMP + H(+); Xref=Rhea:RHEA:54332, ChEBI:CHEBI:15378, ChEBI:CHEBI:58779, ChEBI:CHEBI:60377, ChEBI:CHEBI:74963, ChEBI:CHEBI:82949; Evidence={ECO:0000269|PubMed:10191259};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-choline = 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+); Xref=Rhea:RHEA:54336, ChEBI:CHEBI:15378, ChEBI:CHEBI:58779, ChEBI:CHEBI:60377, ChEBI:CHEBI:83717, ChEBI:CHEBI:84417; Evidence={ECO:0000269|PubMed:10191259};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-ethanolamine = 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+); Xref=Rhea:RHEA:54340, ChEBI:CHEBI:15378, ChEBI:CHEBI:57876, ChEBI:CHEBI:60377, ChEBI:CHEBI:84417, ChEBI:CHEBI:138145; Evidence={ECO:0000269|PubMed:10191259};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1-O-hexadecyl-2-acetyl-sn-glycerol + CDP-choline = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CMP + H(+); Xref=Rhea:RHEA:54348, ChEBI:CHEBI:15378, ChEBI:CHEBI:44811, ChEBI:CHEBI:58779, ChEBI:CHEBI:60377, ChEBI:CHEBI:75936; Evidence={ECO:0000269|PubMed:10893425};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CMP + H(+); Xref=Rhea:RHEA:54352, ChEBI:CHEBI:15378, ChEBI:CHEBI:55430, ChEBI:CHEBI:58779, ChEBI:CHEBI:60377, ChEBI:CHEBI:77184; Evidence={ECO:0000269|PubMed:10893425};.
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=37 uM for CDP-choline {ECO:0000269|PubMed:10191259, ECO:0000269|PubMed:12216837}; KM=101 uM for CDP-ethanolamine {ECO:0000269|PubMed:10191259, ECO:0000269|PubMed:12216837}; Vmax=10.5 nmol/min/mg enzyme with CDP-choline as substrate {ECO:0000269|PubMed:10191259, ECO:0000269|PubMed:12216837}; Vmax=4.35 nmol/min/mg enzyme with CDP-ethanolamine as substrate {ECO:0000269|PubMed:10191259, ECO:0000269|PubMed:12216837};

Enzyme Numbers (IUBMB) for CEPT1 Gene

Phenotypes From GWAS Catalog for CEPT1 Gene

Gene Ontology (GO) - Molecular Function for CEPT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004142 diacylglycerol cholinephosphotransferase activity IBA 21873635
GO:0004307 ethanolaminephosphotransferase activity IBA 21873635
GO:0016740 transferase activity IEA --
GO:0016780 phosphotransferase activity, for other substituted phosphate groups IEA,IBA 21873635
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with CEPT1: view
genes like me logo Genes that share phenotypes with CEPT1: view

Animal Model Products

  • Taconic Biosciences Mouse Models for CEPT1

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CEPT1

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CEPT1 Gene

Localization for CEPT1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CEPT1 Gene

Endoplasmic reticulum membrane. Multi-pass membrane protein. Nucleus membrane. Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CEPT1 gene
Compartment Confidence
endoplasmic reticulum 4
plasma membrane 3
peroxisome 3
nucleus 3
golgi apparatus 3
mitochondrion 2
extracellular 1
cytoskeleton 1
endosome 1
cytosol 1
lysosome 1

Gene Ontology (GO) - Cellular Components for CEPT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005783 endoplasmic reticulum IEA --
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0005794 Golgi apparatus IBA 21873635
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with CEPT1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for CEPT1 Gene

Pathways & Interactions for CEPT1 Gene

genes like me logo Genes that share pathways with CEPT1: view

UniProtKB/Swiss-Prot Q9Y6K0-CEPT1_HUMAN

  • Pathway: Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 3/3.
  • Pathway: Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 2/2.

Gene Ontology (GO) - Biological Process for CEPT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006629 lipid metabolic process TAS 10191259
GO:0006646 phosphatidylethanolamine biosynthetic process IBA,TAS --
GO:0006656 phosphatidylcholine biosynthetic process TAS --
GO:0006657 CDP-choline pathway IEA --
GO:0008654 phospholipid biosynthetic process IEA --
genes like me logo Genes that share ontologies with CEPT1: view

No data available for SIGNOR curated interactions for CEPT1 Gene

Drugs & Compounds for CEPT1 Gene

(7) Drugs for CEPT1 Gene - From: DrugBank and HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Choline Approved Nutra Enzyme, substrate 223
Choline salicylate Approved Nutra Enzyme, substrate 0
Citicoline Approved, Experimental Pharma 0
Magnesium Approved, Experimental, Investigational Pharma 0
Manganese Approved Nutra 56

(11) Additional Compounds for CEPT1 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
  • CDP Ethanolamine
  • Cytidine 5'-(trihydrogen diphosphate), p'-(2-aminoethyl) ester
  • Cytidine diphosphate ethanolamine
  • Cytidine 5'-(trihydrogen diphosphoric acid), p'-(2-aminoethyl) ester
  • Cytidine diphosphoric acid ethanolamine
  • CMPciliatine
  • CMP-2-Aminoethylphosphonic acid
  • CMP-2-Trimethylaminoethylphosphonate
  • CMP-2-Trimethylaminoethylphosphonic acid
  • CMP-N-Trimethyl-2-aminoethylphosphonic acid
  • (2-Acetyloxy-3-octadec-9-enoxypropyl) 2-trimethylazaniumylethyl phosphate
  • 2-Acetyl-1-(9Z-octadecenyl)-sn-glycero-3-phosphocholine
  • PC(O-18:1(9Z)/2:0)
  • 1-(Hexadec-1-enyl)-2-palmitoyl-sn-glycero-3-phosphoethanolamine zwitterion
  • 1-[(1Z)-Hexadec-1-enyl]-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion
  • 1-[(1Z)-Hexadec-1-enyl]-2-palmitoyl-sn-glycero-3-phosphoethanolamine zwitterion
  • PE(P-16:0/16:0)
  • 2-Hexadecanoyl-1-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine
genes like me logo Genes that share compounds with CEPT1: view

Transcripts for CEPT1 Gene

mRNA/cDNA for CEPT1 Gene

10 NCBI additional mRNA sequence :
11 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CEPT1

Alternative Splicing Database (ASD) splice patterns (SP) for CEPT1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c ^ 9
SP1: - - -
SP3: -
SP4: -

Relevant External Links for CEPT1 Gene

GeneLoc Exon Structure for

Expression for CEPT1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CEPT1 Gene

Protein differential expression in normal tissues from HIPED for CEPT1 Gene

This gene is overexpressed in Breast (12.0), Monocytes (11.5), and Placenta (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CEPT1 Gene

Protein tissue co-expression partners for CEPT1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CEPT1

SOURCE GeneReport for Unigene cluster for CEPT1 Gene:


mRNA Expression by UniProt/SwissProt for CEPT1 Gene:

Tissue specificity: Ubiquitously expressed.

Evidence on tissue expression from TISSUES for CEPT1 Gene

  • Bone marrow(4.3)
  • Pancreas(4.1)
  • Liver(2.8)
  • Nervous system(2.5)
  • Kidney(2.2)
  • Intestine(2.2)
genes like me logo Genes that share expression patterns with CEPT1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CEPT1 Gene

Orthologs for CEPT1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for CEPT1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CEPT1 30 31
  • 99.84 (n)
(Ornithorhynchus anatinus)
Mammalia CEPT1 31
  • 97 (a)
(Bos Taurus)
Mammalia CEPT1 30 31
  • 94.47 (n)
(Mus musculus)
Mammalia Cept1 30 17 31
  • 93.83 (n)
(Rattus norvegicus)
Mammalia Cept1 30
  • 93.43 (n)
(Canis familiaris)
Mammalia CEPT1 30 31
  • 92.55 (n)
(Monodelphis domestica)
Mammalia CEPT1 31
  • 92 (a)
(Gallus gallus)
Aves CEPT1 30 31
  • 84.29 (n)
(Anolis carolinensis)
Reptilia CEPT1 31
  • 90 (a)
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia cept1 30
  • 76.36 (n)
Str.8915 30
African clawed frog
(Xenopus laevis)
Amphibia cept1-prov 30
(Danio rerio)
Actinopterygii cept1a 31
  • 74 (a)
cept1b 30 31
  • 70.69 (n)
Dr.669 30
Fruit Fly
(Drosophila melanogaster)
Insecta CG6016 32
  • 54 (a)
bbc 31
  • 50 (a)
(Caenorhabditis elegans)
Secernentea Y49A3A.1 30 32
  • 51.3 (n)
cept-1 31
  • 45 (a)
cept-2 31
  • 42 (a)
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CPT1 31 33
  • 25 (a)
EPT1 31
  • 22 (a)
Thale Cress
(Arabidopsis thaliana)
eudicotyledons AAPT1 30
  • 45.04 (n)
(Oryza sativa)
Liliopsida Os02g0119800 30
  • 45.73 (n)
Bread mold
(Neurospora crassa)
Ascomycetes NCU03223 30
  • 41.3 (n)
Species where no ortholog for CEPT1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for CEPT1 Gene

Gene Tree for CEPT1 (if available)
Gene Tree for CEPT1 (if available)
Evolutionary constrained regions (ECRs) for CEPT1: view image

Paralogs for CEPT1 Gene

Paralogs for CEPT1 Gene

(1) SIMAP similar genes for CEPT1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CEPT1: view

Variants for CEPT1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CEPT1 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
775055 Benign: not provided 111,159,398(+) A/G MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for CEPT1 Gene

Structural Variations from Database of Genomic Variants (DGV) for CEPT1 Gene

Variant ID Type Subtype PubMed ID
esv2455976 CNV deletion 19546169
nsv10639 CNV gain 18304495
nsv1113155 CNV deletion 24896259

Variation tolerance for CEPT1 Gene

Residual Variation Intolerance Score: 26.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.55; 29.96% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CEPT1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CEPT1 Gene

Disorders for CEPT1 Gene

Additional Disease Information for CEPT1

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform

No disorders were found for CEPT1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CEPT1 Gene

Publications for CEPT1 Gene

  1. PC and PE synthesis: mixed micellar analysis of the cholinephosphotransferase and ethanolaminephosphotransferase activities of human choline/ethanolamine phosphotransferase 1 (CEPT1). (PMID: 12216837) Wright MM … McMaster CR (Lipids 2002) 2 3 4 23
  2. The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity. (PMID: 12221122) Henneberry AL … McMaster CR (Molecular biology of the cell 2002) 3 4 23
  3. Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine. (PMID: 10191259) Henneberry AL … McMaster CR (The Biochemical journal 1999) 2 3 4
  4. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. (PMID: 22001757) Chambers JC … Kooner JS (Nature genetics 2011) 3 41
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41

Products for CEPT1 Gene

Sources for CEPT1 Gene