Aliases for CEP350 Gene
Aliases for CEP350 Gene
External Ids for CEP350 Gene
- HGNC: 24238
- Entrez Gene: 9857
- Ensembl: ENSG00000135837
- UniProtKB: Q5VT06
Previous GeneCards Identifiers for CEP350 Gene
- GC01P178190
- GC01P151155
Summaries for CEP350 Gene
-
The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for CEP350 Gene
CEP350 (Centrosomal Protein 350) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include microtubule binding. An important paralog of this gene is CLIP1.
UniProtKB/Swiss-Prot for CEP350 Gene
-
Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ (PubMed:19052644). Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network (PubMed:16314388, PubMed:17878239, PubMed:28659385). Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity (PubMed:15615782). Required for ciliation (PubMed:28659385).
Additional gene information for CEP350 Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CEP350 Gene
Genomics for CEP350 Gene
GeneHancer (GH) Regulatory Elements for CEP350 Gene
Promoters and enhancers for CEP350 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CEP350 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for CEP350 Gene
Genomic Locations for CEP350 Gene
- chr1:179,954,738-180,114,880
- (GRCh38/hg38)
- Size:
- 160,143 bases
- Orientation:
- Plus strand
- chr1:179,923,873-180,084,015
- (GRCh37/hg19)
Genomic View for CEP350 Gene
Genes around CEP350 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q25.2 by Ensembl
- 1q25.2 by Entrez Gene
- 1q25.2 by HGNC
CEP350 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CEP350 Gene
Proteins for CEP350 Gene
-
Protein details for CEP350 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5VT06-CE350_HUMAN
- Recommended name:
- Centrosome-associated protein 350
- Protein Accession:
- Q5VT06
- O75068
- Q8TDK3
- Q8WY20
Protein attributes for CEP350 Gene
- Size:
- 3117 amino acids
- Molecular mass:
- 350930 Da
- Quaternary structure:
-
- Part of a ternary complex that contains CEP350, FGFR1OP and MAPRE1. Interacts (via C-terminus) directly with FGFR1OP (via N-terminus) (PubMed:16314388, PubMed:28625565, PubMed:28428259). Interacts with NR1H3, PPARA, PPARD and PPARG (PubMed:15615782). Interacts directly with microtubules (PubMed:17878239). Interacts with the fusion protein FGFR1OP-FGFR1, and by doing so recruits and activates PI3K and PLC-gamma (PubMed:18412956). Interacts with CYLD (PubMed:25134987). Interacts with CFAP157 (By similarity). Interacts with CEP19 (via C-terminus) (PubMed:28659385).
Protein Expression for CEP350 Gene
Post-translational modifications for CEP350 Gene
- Phosphorylated during mitosis.
- Ubiquitination at Lys250, posLast=663663, Lys686, posLast=829829, and posLast=13181318
- Modification sites at PhosphoSitePlus
Other Protein References for CEP350 Gene
Antibody Products
- Novus Biologicals Antibodies for CEP350
- Invitrogen Antibodies for CEP350
- Search GeneTex for Antibodies for CEP350
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CEP350
- Origene Custom Protein Services for CEP350
- Novus Biologicals proteins for CEP350
- Search GeneTex for Proteins for CEP350
Assay Products
No data available for DME Specific Peptides for CEP350 Gene
Domains & Families for CEP350 Gene
Gene Families for CEP350 Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for CEP350 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CEP350 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for CEP350 Gene
Function for CEP350 Gene
Molecular function for CEP350 Gene
- UniProtKB/Swiss-Prot Function:
- Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ (PubMed:19052644). Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network (PubMed:16314388, PubMed:17878239, PubMed:28659385). Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity (PubMed:15615782). Required for ciliation (PubMed:28659385).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25134987 |
| GO:0008017 | microtubule binding | IEA | -- |
Phenotypes for CEP350 Gene
- GenomeRNAi human phenotypes for CEP350:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CEP350
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CEP350 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CEP350 gene
- Search ViGene Biosciences for CEP350
CRISPR Products
-
OriGene CRISPR knockouts for CEP350
- genomics-online: gRNA clones - Search results for 45 available CEP350 gene related products
- Overview of 45 available CEP350 gene related products
- Applied Biological Materials CRISPR for CEP350
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CEP350
- GenScript: Design CRISPR guide RNA sequences for CEP350
miRNA for CEP350 Gene
- miRTarBase miRNAs that target CEP350
-
- hsa-mir-19b-3p (MIRT031197)
- hsa-mir-1229-3p (MIRT036285)
- hsa-mir-19a-3p (MIRT060822)
- hsa-mir-518a-5p (MIRT060823)
- hsa-mir-527 (MIRT060824)
- hsa-mir-616-3p (MIRT060826)
- hsa-mir-1468-3p (MIRT060827)
- hsa-mir-548f-5p (MIRT060828)
- hsa-mir-548g-5p (MIRT060829)
- hsa-mir-548x-5p (MIRT060830)
- hsa-mir-4289 (MIRT060831)
- hsa-mir-548aj-5p (MIRT060832)
- hsa-mir-4698 (MIRT060833)
- hsa-mir-548aw (MIRT060835)
- hsa-mir-4426 (MIRT060841)
- hsa-mir-4647 (MIRT060843)
- hsa-mir-4662b (MIRT060844)
- hsa-mir-30a-5p (MIRT131793)
- hsa-mir-30c-5p (MIRT131794)
- hsa-mir-30d-5p (MIRT131795)
- hsa-mir-30b-5p (MIRT131796)
- hsa-mir-30e-5p (MIRT131798)
- hsa-mir-153-3p (MIRT367987)
- hsa-mir-648 (MIRT367991)
- hsa-mir-3606-5p (MIRT367993)
- hsa-mir-3658 (MIRT367994)
miRNA Products
- Search ViGene Biosciences for CEP350
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CEP350
- Browse OriGene Inhibitory RNA Products For CEP350
- genomics-online: shRNA clones - Search results for 45 available CEP350 gene related products
- Overview of 45 available CEP350 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CEP350 gene
Clone Products
-
OriGene ORF clones in human for CEP350
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for CEP350
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CEP350
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CEP350
- Applied Biological Materials Clones for CEP350
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for CEP350 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CEP350 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CEP350 gene
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CEP350 Gene
Localization for CEP350 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CEP350 Gene
- Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Associated with mitotic spindles (PubMed:16314388). Nuclear, in discrete foci. Associated with intermediate filaments (PubMed:15615782). Also present in the pericentrosomal area (PubMed:17878239). Localizes on both mother and daughter centrioles. Localizes to an axial position on the mother centriole (PubMed:28625565). Localizes to the distal end of the centriole on the subdistal appendage region (PubMed:28659385). {ECO:0000269 PubMed:15615782, ECO:0000269 PubMed:16314388, ECO:0000269 PubMed:17878239, ECO:0000269 PubMed:28625565, ECO:0000269 PubMed:28659385}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| cytosol | 4 |
- Centrosome (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005813 | centrosome | IEA,IDA | 21399614 |
| GO:0005814 | centriole | IDA,IEA | 28625565 |
| GO:0005815 | microtubule organizing center | IEA | -- |
Pathways & Interactions for CEP350 Gene
No Data Available
Interacting Proteins for CEP350 Gene
Selected Interacting proteins:
ENSP00000356579
Q5VT06-CE350_HUMAN
for CEP350 Gene via
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0034453 | microtubule anchoring | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for CEP350 Gene
Transcripts for CEP350 Gene
mRNA/cDNA for CEP350 Gene
- (6) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (291) Selected AceView cDNA sequences:
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CEP350 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CEP350
- genomics-online: gRNA clones - Search results for 45 available CEP350 gene related products
- Overview of 45 available CEP350 gene related products
- Applied Biological Materials CRISPR for CEP350
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CEP350
- GenScript: Design CRISPR guide RNA sequences for CEP350
miRNA Products
- Search ViGene Biosciences for CEP350
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CEP350
- Browse OriGene Inhibitory RNA Products For CEP350
- genomics-online: shRNA clones - Search results for 45 available CEP350 gene related products
- Overview of 45 available CEP350 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CEP350 gene
Clone Products
-
OriGene ORF clones in human for CEP350
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for CEP350
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CEP350
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CEP350
- Applied Biological Materials Clones for CEP350
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: |
| ExUns: | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33a | · | 33b | ^ | 34a | · | 34b | · | 34c | · | 34d | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38 | ^ | 39 | ^ | 40 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: |
| ExUns: | 41 | ^ | 42 | ^ | 43 | ^ | 44 | ^ | 45 |
|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||
| SP2: | |||||||||
| SP3: | |||||||||
| SP4: | |||||||||
| SP5: | |||||||||
| SP6: | |||||||||
| SP7: | |||||||||
| SP8: | |||||||||
| SP9: | |||||||||
| SP10: | |||||||||
| SP11: |
Expression for CEP350 Gene
This gene is overexpressed in Fetal gut (22.9), NK cells (10.2), Fetal heart (9.3), and Blymphocyte (6.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CEP350 Gene
NURSA nuclear receptor signaling pathways regulating expression of CEP350 Gene:
CEP350SOURCE GeneReport for Unigene cluster for CEP350 Gene:
Hs.413045mRNA Expression by UniProt/SwissProt for CEP350 Gene:
Q5VT06-CE350_HUMAN
Tissue specificity:
Detected in heart, brain, skeletal muscle, testis, placenta, lung, liver, kidney and pancreas.
Evidence on tissue expression from TISSUES for CEP350 Gene
- Blood(4.2)
- Liver(4.2)
- Nervous system(2)
Primer Products
-
OriGene qPCR primer pairs for CEP350
- genomics-online: primer clones - Search results for 45 available CEP350 gene related products
- Overview of 45 available CEP350 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CEP350 Gene
Orthologs for CEP350 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CEP350 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | CEP350 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | CEP350 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Cep350 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cep350 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CEP350 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CEP350 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CEP350 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CEP350 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cep350 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | si:dkey-39n1.3 33 |
|
||
| CEP350 34 |
|
OneToOne | |||
| -- 33 |
|
||||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | NIP100 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for CEP350 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CEP350 Gene
(3) SIMAP similar genes for CEP350 Gene using alignment to 10 proteins:
Variants for CEP350 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000017931 | -- | 179,969,988(+) | A/C/G | intron_variant | |
| rs1000049914 | -- | 180,023,128(+) | G/A | intron_variant | |
| rs1000087497 | -- | 179,977,028(+) | T/C | intron_variant | |
| rs1000154786 | -- | 179,999,623(+) | G/C | intron_variant | |
| rs1000165468 | -- | 179,963,698(+) | T/C | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv656n54 | CNV | loss | 21841781 |
| esv3588061 | CNV | loss | 21293372 |
| nsv1000698 | CNV | loss | 25217958 |
| nsv3755 | CNV | deletion | 18451855 |
| nsv466228 | CNV | loss | 19166990 |
| nsv478740 | CNV | novel sequence insertion | 20440878 |
| nsv520278 | CNV | gain | 19592680 |
| nsv520322 | CNV | loss | 19592680 |
| nsv946526 | CNV | duplication | 23825009 |
| nsv952274 | CNV | duplication | 24416366 |
Residual Variation Intolerance Score:
74% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
9.06;
87.57% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CEP350 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CEP350 Gene
Disorders for CEP350 Gene
Additional Disease Information for CEP350
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for CEP350 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CEP350 Gene
Publications for CEP350 Gene
- A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring. (PMID: 16314388) Yan X … Nigg EA (Molecular biology of the cell 2006) 2 3 4 22 58
- Centrosomal CAP350 protein stabilises microtubules associated with the Golgi complex. (PMID: 17878239) Hoppeler-Lebel A … Tassin AM (Journal of cell science 2007) 3 4 22 58
- Activity and subcellular compartmentalization of peroxisome proliferator-activated receptor alpha are altered by the centrosome-associated protein CAP350. (PMID: 15615782) Patel H … Capone JP (Journal of cell science 2005) 2 3 4 58
- CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme. (PMID: 28659385) Mojarad BA … Pelletier L (Open biology 2017) 3 4 58
- The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. (PMID: 28625565) Kanie T … Jackson PK (Developmental cell 2017) 3 4 58
Products for CEP350 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CEP350
- Origene Custom Protein Services for CEP350
- Origene sirna, shrna, and RNAi products in human, mouse, rat for CEP350
- Browse OriGene Inhibitory RNA Products For CEP350
- OriGene qPCR primer pairs for CEP350
- OriGene CRISPR knockouts for CEP350
- OriGene ORF clones in human for CEP350
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CEP350
- GenScript: Next-day shipping of latest version cDNA ORF clones for CEP350 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CEP350
- GenScript Custom Assay Services for CEP350
- GenScript Custom overexpressing Cell Line Services for CEP350
- GenScript: Design CRISPR guide RNA sequences for CEP350
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CEP350
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for CEP350
- Novus Biologicals proteins for CEP350
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for CEP350
- VectorBuilder custom plasmid, inducible vectors for CEP350
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CEP350
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CEP350
- antibodies-online: Search results for 19 available CEP350 Antibodies ranked by validation data
- Compare Top CEP350 Antibodies
- antibodies-online: Search results for available CEP350 related products ranked by validation data
- antibodies-online: Search results for available CEP350 related products ranked by validation data
- Search GeneTex for Antibodies for CEP350
- Search GeneTex for Proteins for CEP350
- ViGene Biosciences adenoviral particle packaged cDNA for CEP350 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CEP350 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CEP350 gene
- Search ViGene Biosciences for CEP350
- genomics-online: cdna clones - Search results for 45 available CEP350 gene related products
- Overview of 45 available CEP350 gene related products
- orf clones - Search results for 45 available CEP350 gene related products
- Overview of 45 available CEP350 gene related products
- genomics-online: gRNA clones - Search results for 45 available CEP350 gene related products
- Overview of 45 available CEP350 gene related products
- genomics-online: primer clones - Search results for 45 available CEP350 gene related products
- Overview of 45 available CEP350 gene related products
- genomics-online: shRNA clones - Search results for 45 available CEP350 gene related products
- Overview of 45 available CEP350 gene related products
Sources for CEP350 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
