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This locus represents naturally occurring read-through transcription between the neighboring APITD1 (apoptosis-inducing, TAF9-like domain 1) and CORT (cortistatin) genes. Alternative splicing results in multiple transcript variants, two of which encode fusion proteins that share sequence identity with the products of each individual gene. [provided by RefSeq, Aug 2011]
CENPS-CORT (CENPS-CORT Readthrough) is a Protein Coding gene. Among its related pathways are Fanconi anemia pathway. An important paralog of this gene is CENPS.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005179 | hormone activity | IEA | -- |
GO:0046982 | protein heterodimerization activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000776 | kinetochore | IEA | -- |
GO:0005576 | extracellular region | IEA | -- |
GO:0071821 | FANCM-MHF complex | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Fanconi anemia pathway |
Symbol | External ID(s) | Details |
---|---|---|
CCNB1IP1 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006281 | DNA repair | IEA | -- |
GO:0007165 | signal transduction | IEA | -- |
GO:0051382 | kinetochore assembly | IEA | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | APITD1 30 31 |
|
OneToMany | |
Cow (Bos Taurus) |
Mammalia | APITD1 30 31 |
|
OneToMany | |
Dog (Canis familiaris) |
Mammalia | APITD1 30 |
|
||
Rat (Rattus norvegicus) |
Mammalia | Apitd1 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Apitd1 30 31 |
|
OneToMany | |
Cenps 17 |
|
||||
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Chicken (Gallus gallus) |
Aves | APITD1 30 31 |
|
OneToMany | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | apitd1 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | apitd1 30 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2758920 | CNV | gain+loss | 17122850 |
esv2764192 | CNV | gain | 21179565 |
No disorders were found for CENPS-CORT Gene.