Aliases for CENPS Gene
Aliases for CENPS Gene
External Ids for CENPS Gene
- HGNC: 23163
- Entrez Gene: 378708
- Ensembl: ENSG00000175279
- OMIM: 609130
- UniProtKB: Q8N2Z9
Previous HGNC Symbols for CENPS Gene
- APITD1
- MHF1
Summaries for CENPS Gene
-
This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7. [provided by RefSeq, Nov 2010]
GeneCards Summary for CENPS Gene
CENPS (Centromere Protein S) is a Protein Coding gene. Diseases associated with CENPS include Neuroblastoma and Limited Scleroderma. Among its related pathways are Cell Cycle, Mitotic and Fanconi anemia pathway. An important paralog of this gene is CENPS-CORT.
UniProtKB/Swiss-Prot for CENPS Gene
-
DNA-binding component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage (PubMed:20347428, PubMed:20347429). In complex with CENPX (MHF heterodimer), crucial cofactor for FANCM in both binding and ATP-dependent remodeling of DNA. Stabilizes FANCM (PubMed:20347428, PubMed:20347429). In complex with CENPX and FANCM (but not other FANC proteins), rapidly recruited to blocked forks and promotes gene conversion at blocked replication forks (PubMed:20347428). In complex with CENPT, CENPW and CENPX (CENP-T-W-S-X heterotetramer), involved in the formation of a functional kinetochore outer plate, which is essential for kinetochore-microtubule attachment and faithful mitotic progression (PubMed:19620631). As a component of MHF and CENP-T-W-S-X complexes, binds DNA and bends it to form a nucleosome-like structure (PubMed:20347428, PubMed:22304917). DNA-binding function is fulfilled in the presence of CENPX, with the following preference for DNA substates: Holliday junction > double-stranded > splay arm > single-stranded. Does not bind DNA on its own (PubMed:20347428, PubMed:20347429).
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CENPS Gene
Genomics for CENPS Gene
GeneHancer (GH) Regulatory Elements for CENPS Gene
Promoters and enhancers for CENPS Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CENPS on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for CENPS Gene
Genomic Locations for CENPS Gene
- chr1:10,430,102-10,442,815
- (GRCh38/hg38)
- Size:
- 12,714 bases
- Orientation:
- Plus strand
- chr1:10,490,159-10,512,210
- (GRCh37/hg19)
- Size:
- 22,052 bases
- Orientation:
- Plus strand
Genomic View for CENPS Gene
Genes around CENPS on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.22 by Entrez Gene
- 1p36.22 by HGNC
- 1p36.22 by Ensembl
CENPS Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CENPS Gene
Proteins for CENPS Gene
-
Protein details for CENPS Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N2Z9-CENPS_HUMAN
- Recommended name:
- Centromere protein S
- Protein Accession:
- Q8N2Z9
- Q8NFE5
- Q8NFG5
Protein attributes for CENPS Gene
- Size:
- 138 amino acids
- Molecular mass:
- 15893 Da
- Quaternary structure:
-
- Heterodimer with CENPX, sometimes called MHF; this interaction stabilizes both partners (PubMed:19620631, PubMed:20347428, PubMed:20347429, PubMed:24522885). MHF heterodimers can assemble to form tetrameric structures (PubMed:22304917). MHF also coassemble with CENPT-CENPW heterodimers at centromeres to form the tetrameric CENP-T-W-S-X complex (PubMed:22304917, PubMed:24522885). Forms a discrete complex with FANCM and CENPX, called FANCM-MHF; this interaction, probably mediated by direct binding between CENPS and FANCM, leads to synergistic activation of double-stranded DNA binding and strongly stimulates FANCM-mediated DNA remodeling (PubMed:20347428, PubMed:20347429). Recruited by FANCM to the Fanconi anemia (FA) core complex, which consists of CENPS, CENPX, FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM, FAAP24 and FAAP100. The FA core complex associates with Bloom syndrome (BLM) complex, which consists of at least BLM, DNA topoisomerase 3-alpha (TOP3A), RMI1/BLAP75, RPA1/RPA70 and RPA2/RPA32. The super complex between FA and BLM is called BRAFT (PubMed:20347428, PubMed:20347429). Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex, composed of at least CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and CENPU (PubMed:16622419).
Three dimensional structures from OCA and Proteopedia for CENPS Gene
Post-translational modifications for CENPS Gene
Other Protein References for CENPS Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for CENPS
- Invitrogen Antibodies for CENPS
- GeneTex CENPS Antibody for CENPS
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for CENPS
- Origene Custom Protein Services for CENPS
- antibodies-online: Search results for 6 available APITD1 Proteins ranked by validation data
- Compare Top APITD1 Proteins
-
Quality Products:
- Search GeneTex for Proteins for CENPS
Assay Products
No data available for DME Specific Peptides for CENPS Gene
Domains & Families for CENPS Gene
Gene Families for CENPS Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for CENPS Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CENPS Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8N2Z9- Family:
-
- Belongs to the TAF9 family. CENP-S/MHF1 subfamily.
Function for CENPS Gene
Molecular function for CENPS Gene
- UniProtKB/Swiss-Prot Function:
- DNA-binding component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage (PubMed:20347428, PubMed:20347429). In complex with CENPX (MHF heterodimer), crucial cofactor for FANCM in both binding and ATP-dependent remodeling of DNA. Stabilizes FANCM (PubMed:20347428, PubMed:20347429). In complex with CENPX and FANCM (but not other FANC proteins), rapidly recruited to blocked forks and promotes gene conversion at blocked replication forks (PubMed:20347428). In complex with CENPT, CENPW and CENPX (CENP-T-W-S-X heterotetramer), involved in the formation of a functional kinetochore outer plate, which is essential for kinetochore-microtubule attachment and faithful mitotic progression (PubMed:19620631). As a component of MHF and CENP-T-W-S-X complexes, binds DNA and bends it to form a nucleosome-like structure (PubMed:20347428, PubMed:22304917). DNA-binding function is fulfilled in the presence of CENPX, with the following preference for DNA substates: Holliday junction > double-stranded > splay arm > single-stranded. Does not bind DNA on its own (PubMed:20347428, PubMed:20347429).
Phenotypes From GWAS Catalog for CENPS Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA,IDA | 20347429 |
| GO:0003682 | chromatin binding | IDA | 20347429 |
| GO:0003690 | contributes_to double-stranded DNA binding | IDA | 20347428 |
| GO:0005515 | protein binding | IPI | 20347429 |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Phenotypes for CENPS Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CENPS
-
CRISPR Products
-
OriGene CRISPR knockouts for CENPS
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CENPS
- genomics-online: gRNA clones - Search results for available APITD1 gene related products
- Applied Biological Materials CRISPR for CENPS
-
Vectors and viruses for KO, Activation, Repression, and more
- GenScript: Design CRISPR guide RNA sequences for CENPS
miRNA for CENPS Gene
- miRTarBase miRNAs that target CENPS
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CENPS
- Browse OriGene Inhibitory RNA Products For CENPS
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CENPS
- genomics-online: shRNA clones - Search results for available APITD1 gene related products
Clone Products
-
OriGene ORF clones in human for CENPS
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Custom all cDNA clones Services for CENPS
- Sino Biological Human cDNA Clone for CENPS
- VectorBuilder custom plasmid, inducible vectors for CENPS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CENPS
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CENPS
- genomics-online: cdna clones - Search results for available APITD1 gene related products
- orf clones - Search results for available APITD1 gene related products
- Applied Biological Materials Clones for CENPS
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CENPS
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CENPS Gene
Localization for CENPS Gene
Subcellular locations from UniProtKB/Swiss-Prot for CENPS Gene
- Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Assembly of CENPS and CENPX and its partner subunits CENPT and CENPW at centromeres occurs through a dynamic exchange mechanism. Although exchange is continuous in the cell cycle, de novo assembly starts principally during mid-late S phase and is complete by G2. CENPS is more stably bound at the kinetochore than CENPX (PubMed:19620631, PubMed:24522885). During S phase, rapidly recruited to DNA interstrand cross-links that block replication (PubMed:20347428). Recruited to DNA damage sites about 20 minutes following UV irradiation, reaching a plateau after approximately 40 minutes (PubMed:24522885). {ECO:0000269 PubMed:19620631, ECO:0000269 PubMed:20347428, ECO:0000269 PubMed:24522885}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| cytoskeleton | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000775 | chromosome, centromeric region | IEA | -- |
| GO:0000776 | kinetochore | IEA | -- |
| GO:0000777 | condensed chromosome kinetochore | IEA | -- |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CENPS Gene
Pathways & Interactions for CENPS Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cell Cycle, Mitotic |
.83
|
.60
|
| 2 | Chromosome Maintenance | ||
| 3 | Mitotic Metaphase and Anaphase |
.94
|
|
| 4 | Mitotic Prometaphase | ||
| 5 | Fanconi anemia pathway | ||
Pathways by source for CENPS Gene
17 Reactome pathways for CENPS Gene
1 KEGG pathway for CENPS Gene
Interacting Proteins for CENPS Gene
Selected Interacting proteins:
Q8N2Z9-CENPS_HUMAN
ENSP00000308583
for CENPS Gene via
IID
UniProtKB
STRING
MINT
GPS-Prot Interaction Network for CENPS
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000712 | resolution of meiotic recombination intermediates | IMP | 20347428 |
| GO:0006281 | DNA repair | IDA | 20347429 |
| GO:0006312 | mitotic recombination | IBA | -- |
| GO:0006974 | cellular response to DNA damage stimulus | IMP | 20347428 |
| GO:0007049 | cell cycle | IEA | -- |
No data available for SIGNOR curated interactions for CENPS Gene
Transcripts for CENPS Gene
mRNA/cDNA for CENPS Gene
- (1) REFSEQ mRNAs :
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000309048 896 bps (uc001are.4)
- ENST00000462462 584 bps (uc057ccx.2)
- ENST00000464507 684 bps (uc057ccz.1)
- ENST00000477755 914 bps (uc057ccw.2)
- ENST00000602486 312 bps (uc057ccv.1)
CRISPR Products
-
OriGene CRISPR knockouts for CENPS
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CENPS
- genomics-online: gRNA clones - Search results for available APITD1 gene related products
- Applied Biological Materials CRISPR for CENPS
-
Vectors and viruses for KO, Activation, Repression, and more
- GenScript: Design CRISPR guide RNA sequences for CENPS
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CENPS
- Browse OriGene Inhibitory RNA Products For CENPS
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CENPS
- genomics-online: shRNA clones - Search results for available APITD1 gene related products
Clone Products
-
OriGene ORF clones in human for CENPS
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Custom all cDNA clones Services for CENPS
- Sino Biological Human cDNA Clone for CENPS
- VectorBuilder custom plasmid, inducible vectors for CENPS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CENPS
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CENPS
- genomics-online: cdna clones - Search results for available APITD1 gene related products
- orf clones - Search results for available APITD1 gene related products
- Applied Biological Materials Clones for CENPS
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for CENPS Gene
NURSA nuclear receptor signaling pathways regulating expression of CENPS Gene:
CENPSmRNA Expression by UniProt/SwissProt for CENPS Gene:
Q8N2Z9-CENPS_HUMAN
Tissue specificity:
Ubiquitously expressed.
Evidence on tissue expression from TISSUES for CENPS Gene
- Kidney(4)
Primer Products
-
OriGene qPCR primer pairs and template standards for CENPS
-
OriGene qPCR primer pairs for CENPS
- genomics-online: primer clones - Search results for available APITD1 gene related products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for CENPS Gene
Orthologs for CENPS Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | APITD1 34 33 |
|
OneToMany | |
| cow (Bos Taurus) |
Mammalia | APITD1 34 33 |
|
OneToMany | |
| dog (Canis familiaris) |
Mammalia | APITD1 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Apitd1 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Apitd1 34 33 |
|
OneToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | APITD1 34 33 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | apitd1 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | apitd1 34 33 |
|
OneToMany |
- Species where no ortholog for CENPS was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for CENPS Gene
- ENSEMBL:
- Gene Tree for CENPS (if available)
- TreeFam:
- Gene Tree for CENPS (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CENPS: view image
Paralogs for CENPS Gene
Paralogs for CENPS Gene
Pseudogenes.org Pseudogenes for CENPS Gene
Variants for CENPS Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000356299 | -- | 10,442,091(+) | G/A | intron_variant | |
| rs1000780672 | -- | 10,437,962(+) | A/G | intron_variant | |
| rs1000904944 | -- | 10,431,427(+) | C/T | intron_variant | |
| rs1001668937 | -- | 10,431,301(+) | A/G | intron_variant, non_coding_transcript_variant | |
| rs1001902326 | -- | 10,436,788(+) | A/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2758920 | CNV | gain+loss | 17122850 |
| esv2764192 | CNV | gain | 21179565 |
Residual Variation Intolerance Score:
53.3% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CENPS Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CENPS
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CENPS Gene
Disorders for CENPS Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| neuroblastoma |
|
|
| limited scleroderma |
|
|
| fanconi anemia, complementation group a |
|
|
Search CENPS in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CENPS
No data available for UniProtKB/Swiss-Prot and Genatlas for CENPS Gene
Publications for CENPS Gene
- A novel 1p36.2 located gene, APITD1, with tumour-suppressive properties and a putative p53-binding domain, shows low expression in neuroblastoma tumours. (PMID: 15328517) Krona C … Martinsson T (British journal of cancer 2004) 2 3 4 22 58
- A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle. (PMID: 24522885) Dornblut C … Sullivan KF (Open biology 2014) 2 3 4 58
- FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers. (PMID: 25038251) Girard C … Mercier R (Nucleic acids research 2014) 2 3 58
- CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold. (PMID: 22304917) Nishino T … Fukagawa T (Cell 2012) 3 4 58
- MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM. (PMID: 20347429) Singh TR … Meetei AR (Molecular cell 2010) 3 4 58
Products for CENPS Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for CENPS
- Origene Custom Protein Services for CENPS
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CENPS
- Browse OriGene Inhibitory RNA Products For CENPS
- OriGene qPCR primer pairs and template standards for CENPS
- OriGene qPCR primer pairs for CENPS
- OriGene CRISPR knockouts for CENPS
- OriGene ORF clones in human for CENPS
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CENPS
- GenScript: Custom all cDNA clones Services for CENPS
- GenScript Custom Purified and Recombinant Proteins Services for CENPS
- GenScript Custom Assay Services for CENPS
- GenScript Custom overexpressing Cell Line Services for CENPS
- GenScript: Design CRISPR guide RNA sequences for CENPS
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CENPS
- Sino Biological Human cDNA Clone for CENPS
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for CENPS
- Novus Biologicals proteins and lysates for CENPS
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder custom plasmid, inducible vectors for CENPS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CENPS
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 25 available APITD1 Antibodies ranked by validation data
- Compare Top APITD1 Antibodies
- antibodies-online: Search results for 15 available APITD1 Elisa Kits ranked by validation data
- Compare Top APITD1 Elisa Kits
- antibodies-online: Search results for 6 available APITD1 Proteins ranked by validation data
- Compare Top APITD1 Proteins
- Quality Products:
- GeneTex CENPS Antibody for CENPS
- Search GeneTex for Proteins for CENPS
- Horizon Cell Lines for CENPS
- genomics-online: cdna clones - Search results for available APITD1 gene related products
- orf clones - Search results for available APITD1 gene related products
- genomics-online: gRNA clones - Search results for available APITD1 gene related products
- genomics-online: primer clones - Search results for available APITD1 gene related products
- genomics-online: shRNA clones - Search results for available APITD1 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CENPS
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CENPS
- GeneCopoeia miRNA 3'UTR Target clone products for CENPS
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CENPS
Sources for CENPS Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt