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Aliases for CENPJ Gene

Aliases for CENPJ Gene

  • Centromere Protein J 2 3 3 5
  • Centrosomal P4.1-Associated Protein 2 3 4
  • LYST-Interacting Protein 1 3 4
  • LAG-3-Associated Protein 3 4
  • CENP-J 3 4
  • CPAP 3 4
  • LIP1 3 4
  • LAP 3 4
  • Microcephaly, Primary Autosomal Recessive 6 2
  • LYST-Interacting Protein LIP1 3
  • LYST-Interacting Protein LIP7 3
  • BM032 3
  • SASS4 3
  • SCKL4 3
  • Sas-4 3
  • MCPH6 3

External Ids for CENPJ Gene

Previous HGNC Symbols for CENPJ Gene

  • MCPH6

Previous GeneCards Identifiers for CENPJ Gene

  • GC13M023437
  • GC13M019437
  • GC13M024387
  • GC13M023255
  • GC13M024355
  • GC13M025456
  • GC13M006269

Summaries for CENPJ Gene

Entrez Gene Summary for CENPJ Gene

  • This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and cognitive disability. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]

GeneCards Summary for CENPJ Gene

CENPJ (Centromere Protein J) is a Protein Coding gene. Diseases associated with CENPJ include Microcephaly 6, Primary, Autosomal Recessive and Seckel Syndrome 4. Among its related pathways are Gene Expression and Cell Cycle, Mitotic. Gene Ontology (GO) annotations related to this gene include protein kinase binding and tubulin binding.

UniProtKB/Swiss-Prot for CENPJ Gene

  • Plays an important role in cell division and centrosome function by participating in centriole duplication (PubMed:17681131, PubMed:20531387). Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles (PubMed:15047868, PubMed:27219064, PubMed:27306797). Required for centriole elongation and for STIL-mediated centriole amplification (PubMed:22020124). May be involved in the control of centriolar-microtubule growth by acting as a regulator of tubulin release (PubMed:27306797).

Gene Wiki entry for CENPJ Gene

Additional gene information for CENPJ Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CENPJ Gene

Genomics for CENPJ Gene

GeneHancer (GH) Regulatory Elements for CENPJ Gene

Promoters and enhancers for CENPJ Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J024921 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 656 -0.2 -247 2.6 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 IRF4 YY1 POLR2B CENPJ TPTE2P1 RNF17 ENSG00000273628
GH13J024922 Enhancer 0.5 Ensembl 655.9 +1.8 1788 0.2 ATF4 IKZF1 CEBPG EP300 CENPJ TPTE2P1 PIR31198 GC13P024800
GH13J024097 Enhancer 0.8 ENCODE 11 +825.3 825281 0.7 RAD21 YY1 SCRT2 ATF7 RUNX3 EGR2 RXRA CEBPB REST NFIL3 CENPJ IPO7P2 PIR59399 SPATA13 ENSG00000273167
GH13J024968 Promoter 0.9 Ensembl 9.6 -45.4 -45412 0.6 CTCF ZNF654 REST RAD21 FOXA1 ZSCAN21 KLF9 ZNF143 ZNF444 FOXP1 TPTE2P1 CENPJ SLC25A15P3
GH13J024957 Enhancer 0.6 ENCODE 5.4 -34.3 -34289 0.2 CTBP1 SMARCA4 IKZF1 CBFA2T3 FEZF1 PRDM10 ZEB2 SPI1 CENPJ SLC25A15P3 TPTE2P1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CENPJ on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CENPJ gene promoter:
  • p300
  • STAT3
  • LCR-F1
  • AML1a
  • FOXJ2
  • FOXJ2 (long isoform)
  • GATA-3

Genomic Locations for CENPJ Gene

Genomic Locations for CENPJ Gene
chr13:24,882,274-24,922,889
(GRCh38/hg38)
Size:
40,616 bases
Orientation:
Minus strand
chr13:25,456,412-25,497,085
(GRCh37/hg19)
Size:
40,674 bases
Orientation:
Minus strand

Genomic View for CENPJ Gene

Genes around CENPJ on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CENPJ Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CENPJ Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CENPJ Gene

Proteins for CENPJ Gene

  • Protein details for CENPJ Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HC77-CENPJ_HUMAN
    Recommended name:
    Centromere protein J
    Protein Accession:
    Q9HC77
    Secondary Accessions:
    • Q2KHM6
    • Q5JPD5
    • Q5T6R5
    • Q96KS5
    • Q9C067

    Protein attributes for CENPJ Gene

    Size:
    1338 amino acids
    Molecular mass:
    153000 Da
    Quaternary structure:
    • Forms homodimers (PubMed:27219064). Associates with microtubules plus ends; binds to beta-tublin subunits exposed on microtubule outer surface at its distal tip; also associates with microtubule lattice (PubMed:19131341, PubMed:27219064, PubMed:27306797). Associated with the gamma-tubulin complex. Interacts with the head domain of EPB41 (PubMed:11003675). Interacts with LYST (PubMed:11984006). Interacts with CEP152 (via C-terminus) (PubMed:20852615). Interacts with STIL (PubMed:22020124, PubMed:25385835). Forms a complex with STIL and SASS6 (PubMed:22020124).
    SequenceCaution:
    • Sequence=AAH24209.3; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for CENPJ Gene

    Alternative splice isoforms for CENPJ Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CENPJ Gene

Post-translational modifications for CENPJ Gene

  • Phosphorylation at Ser-589 and Ser-595 by PLK2 is required for procentriole formation and centriole elongation. Phosphorylation by PLK2 oscillates during the cell cycle: it increases at G1/S transition and decreases during the exit from mitosis. Phosphorylation at Ser-595 is also mediated by PLK4 but is not a critical step in PLK4 function in procentriole assembly.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CENPJ Gene

No data available for DME Specific Peptides for CENPJ Gene

Domains & Families for CENPJ Gene

Gene Families for CENPJ Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Predicted intracellular proteins

Protein Domains for CENPJ Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CENPJ Gene

Graphical View of Domain Structure for InterPro Entry

Q9HC77

UniProtKB/Swiss-Prot:

CENPJ_HUMAN :
  • Belongs to the TCP10 family.
Family:
  • Belongs to the TCP10 family.
genes like me logo Genes that share domains with CENPJ: view

Function for CENPJ Gene

Molecular function for CENPJ Gene

UniProtKB/Swiss-Prot Function:
Plays an important role in cell division and centrosome function by participating in centriole duplication (PubMed:17681131, PubMed:20531387). Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles (PubMed:15047868, PubMed:27219064, PubMed:27306797). Required for centriole elongation and for STIL-mediated centriole amplification (PubMed:22020124). May be involved in the control of centriolar-microtubule growth by acting as a regulator of tubulin release (PubMed:27306797).

Gene Ontology (GO) - Molecular Function for CENPJ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 11003675
GO:0015631 tubulin binding IDA,IEA 15047868
GO:0019901 protein kinase binding IPI 20531387
GO:0019904 protein domain specific binding IPI 11984006
GO:0042802 identical protein binding IPI 24076405
genes like me logo Genes that share ontologies with CENPJ: view
genes like me logo Genes that share phenotypes with CENPJ: view

Human Phenotype Ontology for CENPJ Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for CENPJ Gene

MGI Knock Outs for CENPJ:
  • Cenpj Cenpj<tm1a(EUCOMM)Wtsi>
  • Cenpj Cenpj<tm1d(EUCOMM)Wtsi>
  • Cenpj Cenpj<tm1.1Tkt>
  • Cenpj Cenpj<tm1b(EUCOMM)Wtsi>

Animal Model Products

Clone Products

  • Addgene plasmids for CENPJ

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Transcription Factor Targets and HOMER Transcription for CENPJ Gene

Localization for CENPJ Gene

Subcellular locations from UniProtKB/Swiss-Prot for CENPJ Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localized within the center of microtubule asters (PubMed:11003675). During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles (PubMed:17681131). {ECO:0000269 PubMed:11003675, ECO:0000269 PubMed:17681131}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CENPJ gene
Compartment Confidence
cytoskeleton 5
nucleus 5
cytosol 5
plasma membrane 4

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centrosome (3)
  • Nucleoplasm (1)
  • Plasma membrane (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CENPJ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IEA --
GO:0005813 centrosome IDA 21399614
GO:0005814 centriole IDA,IEA 17681131
GO:0005815 microtubule organizing center IEA --
genes like me logo Genes that share ontologies with CENPJ: view

Pathways & Interactions for CENPJ Gene

genes like me logo Genes that share pathways with CENPJ: view

SIGNOR curated interactions for CENPJ Gene

Is activated by:

Gene Ontology (GO) - Biological Process for CENPJ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000086 G2/M transition of mitotic cell cycle TAS --
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS --
GO:0007020 microtubule nucleation TAS 11003675
GO:0007099 centriole replication IMP 17681131
GO:0007224 smoothened signaling pathway IEA --
genes like me logo Genes that share ontologies with CENPJ: view

Drugs & Compounds for CENPJ Gene

No Compound Related Data Available

Transcripts for CENPJ Gene

Unigene Clusters for CENPJ Gene

Centromere protein J:
Representative Sequences:

Clone Products

  • Addgene plasmids for CENPJ

Alternative Splicing Database (ASD) splice patterns (SP) for CENPJ Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17
SP1: - -
SP2: - -
SP3: -
SP4:
SP5: -

Relevant External Links for CENPJ Gene

GeneLoc Exon Structure for
CENPJ
ECgene alternative splicing isoforms for
CENPJ

Expression for CENPJ Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CENPJ Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CENPJ Gene

This gene is overexpressed in Cervix (48.0) and Fetal Brain (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CENPJ Gene



NURSA nuclear receptor signaling pathways regulating expression of CENPJ Gene:

CENPJ

SOURCE GeneReport for Unigene cluster for CENPJ Gene:

Hs.741581

Evidence on tissue expression from TISSUES for CENPJ Gene

  • Lymph node(4.1)
  • Muscle(4.1)
  • Nervous system(4)

Phenotype-based relationships between genes and organs from Gene ORGANizer for CENPJ Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • immune
  • integumentary
  • lymphatic
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • cerebellum
  • cheek
  • chin
  • cranial nerve
  • ear
  • eye
  • eyelid
  • face
  • forehead
  • head
  • jaw
  • larynx
  • lip
  • mandible
  • maxilla
  • mouth
  • neck
  • nose
  • outer ear
  • skull
  • tongue
  • tooth
  • vocal cord
Thorax:
  • chest wall
  • clavicle
  • heart
  • heart valve
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
Abdomen:
  • kidney
Pelvis:
  • pelvis
  • penis
  • testicle
  • ureter
  • urethra
  • vagina
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • blood
  • bone marrow
  • coagulation system
  • hair
  • peripheral nerve
  • peripheral nervous system
  • red blood cell
  • skin
  • spinal column
  • spinal cord
  • vertebrae
  • white blood cell
genes like me logo Genes that share expression patterns with CENPJ: view

No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for CENPJ Gene

Orthologs for CENPJ Gene

This gene was present in the common ancestor of animals.

Orthologs for CENPJ Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CENPJ 34 33
  • 99.53 (n)
OneToOne
dog
(Canis familiaris)
Mammalia CENPJ 34 33
  • 85.8 (n)
OneToOne
cow
(Bos Taurus)
Mammalia CENPJ 34 33
  • 82.37 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Cenpj 16 34 33
  • 79.84 (n)
rat
(Rattus norvegicus)
Mammalia Cenpj 33
  • 78.75 (n)
oppossum
(Monodelphis domestica)
Mammalia CENPJ 34
  • 62 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CENPJ 34
  • 54 (a)
OneToOne
chicken
(Gallus gallus)
Aves CENPJ 34 33
  • 61.99 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CENPJ 34
  • 41 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100491003 33
  • 55.46 (n)
Str.1652 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.13927 33
zebrafish
(Danio rerio)
Actinopterygii cenpj 34 33
  • 54.53 (n)
OneToOne
wufi46g11 33
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10651 33
fruit fly
(Drosophila melanogaster)
Insecta CG10061 35
  • 45 (a)
Sas-4 34
  • 21 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 37 (a)
OneToOne
Species where no ortholog for CENPJ was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CENPJ Gene

ENSEMBL:
Gene Tree for CENPJ (if available)
TreeFam:
Gene Tree for CENPJ (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CENPJ: view image

Paralogs for CENPJ Gene

(1) SIMAP similar genes for CENPJ Gene using alignment to 4 proteins:

  • CENPJ_HUMAN
  • H0Y5L8_HUMAN
  • Q2KHM5_HUMAN
  • Q569I1_HUMAN

Pseudogenes.org Pseudogenes for CENPJ Gene

genes like me logo Genes that share paralogs with CENPJ: view

No data available for Paralogs for CENPJ Gene

Variants for CENPJ Gene

Sequence variations from dbSNP and Humsavar for CENPJ Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1018312277 uncertain-significance, Primary Microcephaly, Recessive, Seckel syndrome 24,882,713(-) T/C 3_prime_UTR_variant, genic_downstream_transcript_variant, non_coding_transcript_variant
rs1060499557 pathogenic, Seckel syndrome 5 24,883,255(-) ATGA/ coding_sequence_variant, frameshift, genic_downstream_transcript_variant, non_coding_transcript_variant
rs112133852 benign, uncertain-significance, not specified, Seckel syndrome, Primary Microcephaly, Recessive 24,906,805(-) C/T coding_sequence_variant, non_coding_transcript_variant, synonymous_variant
rs113239817 uncertain-significance, likely-benign, Primary Microcephaly, Recessive, Seckel syndrome, not specified 24,883,234(-) G/A coding_sequence_variant, genic_downstream_transcript_variant, non_coding_transcript_variant, synonymous_variant
rs115628561 uncertain-significance, Primary autosomal recessive microcephaly 6 24,906,628(-) C/T coding_sequence_variant, non_coding_transcript_variant, synonymous_variant

Structural Variations from Database of Genomic Variants (DGV) for CENPJ Gene

Variant ID Type Subtype PubMed ID
esv3550197 CNV deletion 23714750
nsv1041986 CNV gain 25217958
nsv1053023 CNV gain 25217958
nsv1116459 OTHER inversion 24896259
nsv1153497 OTHER inversion 26484159
nsv472625 CNV novel sequence insertion 20440878

Variation tolerance for CENPJ Gene

Residual Variation Intolerance Score: 84.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.16; 69.49% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CENPJ Gene

Human Gene Mutation Database (HGMD)
CENPJ
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CENPJ

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CENPJ Gene

Disorders for CENPJ Gene

MalaCards: The human disease database

(10) MalaCards diseases for CENPJ Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search CENPJ in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

CENPJ_HUMAN
  • Microcephaly 6, primary, autosomal recessive (MCPH6) [MIM:608393]: A disease defined as a head circumference more than 3 standard deviations below the age-related mean. Brain weight is markedly reduced and the cerebral cortex is disproportionately small. Despite this marked reduction in size, the gyral pattern is relatively well preserved, with no major abnormality in cortical architecture. Affected individuals are mentally retarded. Primary microcephaly is further defined by the absence of other syndromic features or significant neurological deficits due to degenerative brain disorder. {ECO:0000269 PubMed:15793586, ECO:0000269 PubMed:22020124}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Seckel syndrome 4 (SCKL4) [MIM:613676]: A rare autosomal recessive disorder characterized by proportionate dwarfism of prenatal onset associated with low birth weight, growth retardation, severe microcephaly with a bird-headed like appearance, and mental retardation. {ECO:0000269 PubMed:20522431}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for CENPJ

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with CENPJ: view

No data available for Genatlas for CENPJ Gene

Publications for CENPJ Gene

  1. Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex. (PMID: 11003675) Hung LY … Tang TK (Molecular and cellular biology 2000) 2 3 4 22 58
  2. The PN2-3 domain of centrosomal P4.1-associated protein implements a novel mechanism for tubulin sequestration. (PMID: 19131341) Cormier A … Curmi PA (The Journal of biological chemistry 2009) 3 4 22 58
  3. Plk4-induced centriole biogenesis in human cells. (PMID: 17681131) Kleylein-Sohn J … Nigg EA (Developmental cell 2007) 3 4 22 58
  4. A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size. (PMID: 15793586) Bond J … Woods CG (Nature genetics 2005) 3 4 22 58
  5. Identification of a novel microtubule-destabilizing motif in CPAP that binds to tubulin heterodimers and inhibits microtubule assembly. (PMID: 15047868) Hung LY … Tang TK (Molecular biology of the cell 2004) 3 4 22 58

Products for CENPJ Gene

  • Addgene plasmids for CENPJ

Sources for CENPJ Gene

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