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Aliases for CENPBD1 Gene

Aliases for CENPBD1 Gene

  • CENPB DNA-Binding Domain Containing 1 2 3 5
  • CENPB DNA-Binding Domains Containing 1 2 3
  • CENPB DNA-Binding Domain-Containing Protein 1 3

External Ids for CENPBD1 Gene

Previous GeneCards Identifiers for CENPBD1 Gene

  • GC16M088567
  • GC16M090036
  • GC16M075729

Summaries for CENPBD1 Gene

GeneCards Summary for CENPBD1 Gene

CENPBD1 (CENPB DNA-Binding Domain Containing 1) is a Protein Coding gene.

Additional gene information for CENPBD1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CENPBD1 Gene

Genomics for CENPBD1 Gene

GeneHancer (GH) Regulatory Elements for CENPBD1 Gene

Promoters and enhancers for CENPBD1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J089971 Promoter/Enhancer 1.6 Ensembl ENCODE 662.1 -0.6 -631 4.8 HDGF PKNOX1 CLOCK SMAD1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 AFG3L1P CENPBD1 ANKRD11 ENSG00000268218 TCF25 DEF8 MC1R ZNF778 LOC101927863 ENSG00000259006
GH16J089947 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 5 +24.0 24015 2.4 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A ZNF2 ZBTB7B ZNF207 ZNF143 DEF8 CDK10 MC1R ACSF3 ANKRD11 ZNF778 TCF25 ENSG00000268218 SNORD68 LOC101927863
GH16J089993 Enhancer 1.5 Ensembl ENCODE dbSUPER 5.2 -22.4 -22415 3.5 HDGF PKNOX1 CLOCK FOXA2 ARNT ZFP64 ARID4B SIN3A ZNF2 ZBTB7B PIR44838 AFG3L1P ENSG00000259877 ANKRD11 MC1R ACSF3 TCF25 LOC101927863 ENSG00000268218 SNORD68
GH16J089931 Enhancer 0.5 dbSUPER 13.3 +40.5 40497 1.5 BCOR POLR2A ZMYM3 EBF1 KDM1A DEF8 AFG3L1P CENPBD1 CDK10 MC1R ENSG00000259006 GC16P089938 ENSG00000198211 TUBB3
GH16J089711 Promoter/Enhancer 1.3 Ensembl ENCODE 4.6 +260.7 260721 2 HDAC1 RB1 SIN3A ZBTB7B ZNF121 POLR2B EGR1 SCRT2 ZFP91 SMARCA5 VPS9D1-AS1 CDK10 TUBB3 GALNS CENPBD1 VPS9D1 ZNF276
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CENPBD1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CENPBD1 Gene

Genomic Locations for CENPBD1 Gene
chr16:89,969,773-89,972,832
(GRCh38/hg38)
Size:
3,060 bases
Orientation:
Minus strand
chr16:90,036,183-90,039,240
(GRCh37/hg19)

Genomic View for CENPBD1 Gene

Genes around CENPBD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CENPBD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CENPBD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CENPBD1 Gene

Proteins for CENPBD1 Gene

  • Protein details for CENPBD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B2RD01-CENP1_HUMAN
    Recommended name:
    CENPB DNA-binding domain-containing protein 1
    Protein Accession:
    B2RD01

    Protein attributes for CENPBD1 Gene

    Size:
    187 amino acids
    Molecular mass:
    21052 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CENPBD1 Gene

Post-translational modifications for CENPBD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CENPBD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CENPBD1 Gene

Domains & Families for CENPBD1 Gene

Gene Families for CENPBD1 Gene

Protein Domains for CENPBD1 Gene

Suggested Antigen Peptide Sequences for CENPBD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CENPBD1: view

No data available for UniProtKB/Swiss-Prot for CENPBD1 Gene

Function for CENPBD1 Gene

Gene Ontology (GO) - Molecular Function for CENPBD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
genes like me logo Genes that share ontologies with CENPBD1: view
genes like me logo Genes that share phenotypes with CENPBD1: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CENPBD1 Gene

Localization for CENPBD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CENPBD1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CENPBD1 gene
Compartment Confidence
nucleus 4
cytosol 2
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CENPBD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with CENPBD1: view

Pathways & Interactions for CENPBD1 Gene

SuperPathways for CENPBD1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CENPBD1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CENPBD1 Gene

Drugs & Compounds for CENPBD1 Gene

No Compound Related Data Available

Transcripts for CENPBD1 Gene

mRNA/cDNA for CENPBD1 Gene

(61) Selected AceView cDNA sequences:
(6) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CENPBD1 Gene

CENPB DNA-binding domains containing 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CENPBD1 Gene

No ASD Table

Relevant External Links for CENPBD1 Gene

GeneLoc Exon Structure for
CENPBD1
ECgene alternative splicing isoforms for
CENPBD1

Expression for CENPBD1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CENPBD1 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CENPBD1 Gene



NURSA nuclear receptor signaling pathways regulating expression of CENPBD1 Gene:

CENPBD1

SOURCE GeneReport for Unigene cluster for CENPBD1 Gene:

Hs.513832
genes like me logo Genes that share expression patterns with CENPBD1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CENPBD1 Gene

Orthologs for CENPBD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CENPBD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CENPBD1 33
  • 63.53 (n)
cow
(Bos Taurus)
Mammalia CENPBD1 34
  • 53 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CENPBD1 34
  • 46 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CENPBD1 34
  • 8 (a)
OneToOne
Species where no ortholog for CENPBD1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CENPBD1 Gene

ENSEMBL:
Gene Tree for CENPBD1 (if available)
TreeFam:
Gene Tree for CENPBD1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CENPBD1: view image

Paralogs for CENPBD1 Gene

(1) SIMAP similar genes for CENPBD1 Gene using alignment to 1 proteins:

  • CENP1_HUMAN

Pseudogenes.org Pseudogenes for CENPBD1 Gene

genes like me logo Genes that share paralogs with CENPBD1: view

No data available for Paralogs for CENPBD1 Gene

Variants for CENPBD1 Gene

Sequence variations from dbSNP and Humsavar for CENPBD1 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000069914 -- 89,969,866(-) C/G 3_prime_UTR_variant
rs1000464059 -- 89,972,592(-) C/T 5_prime_UTR_variant
rs1000744164 -- 89,973,444(-) G/A upstream_transcript_variant
rs1000794050 -- 89,972,738(-) C/T 5_prime_UTR_variant
rs1001177971 -- 89,973,271(-) C/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CENPBD1 Gene

Variant ID Type Subtype PubMed ID
esv2762221 CNV gain+loss 21179565
esv3639603 CNV gain 21293372
esv3892941 CNV gain 25118596
nsv1066499 CNV loss 25217958
nsv428331 CNV gain+loss 18775914
nsv457626 CNV loss 19166990
nsv471119 CNV loss 18288195
nsv482951 CNV loss 15286789
nsv509640 CNV insertion 20534489
nsv573799 CNV gain 21841781
nsv573810 CNV loss 21841781
nsv573841 CNV loss 21841781
nsv573842 CNV loss 21841781

Variation tolerance for CENPBD1 Gene

Gene Damage Index Score: 3.90; 59.28% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CENPBD1 Gene

Human Gene Mutation Database (HGMD)
CENPBD1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CENPBD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CENPBD1 Gene

Disorders for CENPBD1 Gene

Additional Disease Information for CENPBD1

No disorders were found for CENPBD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CENPBD1 Gene

Publications for CENPBD1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. (PMID: 14667819) Lehner B … Sanderson CM (Genomics 2004) 3 58
  3. A protein interaction framework for human mRNA degradation. (PMID: 15231747) Lehner B … Sanderson CM (Genome research 2004) 3 58
  4. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for CENPBD1 Gene

Sources for CENPBD1 Gene

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