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CECR7 Gene(RNA Gene)

Cat Eye Syndrome Chromosome Region, Candidate 7

GCID:
GC22P017048
GIFtS:
18
Genes Participants
UDN Logo

Aliases for CECR7 Gene

Subcategory (RNA class) for CECR7 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for CECR7 Gene

  • Cat Eye Syndrome Chromosome Region, Candidate 7 2 2 3
  • Cat Eye Syndrome Chromosome Region, Candidate 7 (Non-Protein Coding) 2 3 5
  • Cytochrome C-Like Antigen 3
  • SAHL1 3
  • CYCL 3

External Ids for CECR7 Gene

Previous GeneCards Identifiers for CECR7 Gene

  • GC22P014461
  • GC22P015892
  • GC22U900116
  • GC22P017517
  • GC22P001336

Summaries for CECR7 Gene

GeneCards Summary for CECR7 Gene

CECR7 (Cat Eye Syndrome Chromosome Region, Candidate 7) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with CECR7 include Hepatocellular Carcinoma and Cat Eye Syndrome.

Additional gene information for CECR7 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CECR7 Gene

Genomics for CECR7 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for CECR7 Gene

Promoters and enhancers for CECR7 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH22J017036 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 677.1 +0.4 378 1.9 ATF1 NFRKB SIN3A EGR1 ARID2 ZNF143 ZFP91 IKZF2 ZNF592 NFIC CECR7 IL17RA PIR45862
GH22J017084 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 29.7 +49.7 49717 4.3 HDGF PKNOX1 SIN3A DMAP1 IRF4 POLR2B ZNF143 ZNF263 SP3 REST IL17RA CECR7 ENSG00000273203 ADA2 CECR2 RPL31P62
GH22J017074 Enhancer 1.2 Ensembl ENCODE dbSUPER 19.2 +38.9 38856 1.2 ARNT KLF17 RAD21 ZNF335 ARID2 SCRT2 EGR2 ZNF654 YY2 REST CECR7 LINC01664 TMEM121B ADA2 CECR3 ENSG00000273203 ENSG00000273442
GH22J017063 Enhancer 0.7 Ensembl ENCODE 31.7 +27.7 27661 2.1 JUN MAX CBFA2T3 EGR2 CECR7 ENSG00000273203 PIR31163
GH22J018020 Enhancer 0.8 dbSUPER 10.3 +985.0 985012 1.3 ZNF493 ZFP64 MZF1 ZEB1 ZNF155 ZNF121 ZNF213 ZNF138 ZNF366 KLF7 RHEBP3 LINC01634 ENSG00000273203 MICAL3 PEX26 ENSG00000225335 ENSG00000236890 ENSG00000273442 CECR7 LOC102725072
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CECR7 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CECR7 gene promoter:
  • LCR-F1
  • AP-4
  • SREBP-1c
  • SREBP-1b
  • SREBP-1a
  • MyoD
  • Zic1
  • ZIC2
  • Roaz

Genomic Locations for CECR7 Gene

Genomic Locations for CECR7 Gene
chr22:17,036,570-17,060,825
(GRCh38/hg38)
Size:
24,256 bases
Orientation:
Plus strand
chr22:17,517,460-17,541,715
(GRCh37/hg19)
Size:
24,256 bases
Orientation:
Plus strand

Genomic View for CECR7 Gene

Genes around CECR7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CECR7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CECR7 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for CECR7 Gene

Proteins for CECR7 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for CECR7 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CECR7 Gene

Domains & Families for CECR7 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CECR7 Gene

Function for CECR7 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for CECR7 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CECR7 Gene

Localization for CECR7 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CECR7 Gene

Pathways & Interactions for CECR7 Gene

SuperPathways for CECR7 Gene

PathCards logo More details on SuperPathways for CECR7
No Data Available

Interacting Proteins for CECR7 Gene

Gene Ontology (GO) - Biological Process for CECR7 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CECR7 Gene

Drugs & Compounds for CECR7 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for CECR7 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for CECR7 Gene

(6) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(3) RNA Central transcripts :

Unigene Clusters for CECR7 Gene

Cat eye syndrome chromosome region, candidate 7 (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CECR7 Gene

No ASD Table

Relevant External Links for CECR7 Gene

GeneLoc Exon Structure for
CECR7
ECgene alternative splicing isoforms for
CECR7

Expression for CECR7 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CECR7 Gene

mRNA expression in normal human tissues for CECR7 Gene
mRNA expression by GTEx for CECR7 Gene

NURSA nuclear receptor signaling pathways regulating expression of CECR7 Gene:

CECR7

SOURCE GeneReport for Unigene cluster for CECR7 Gene:

Hs.660640
genes like me logo Genes that share expression patterns with CECR7: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CECR7 Gene

Orthologs for CECR7 Gene

Evolution for CECR7 Gene

ENSEMBL:
Gene Tree for CECR7 (if available)
TreeFam:
Gene Tree for CECR7 (if available)

No data available for Orthologs for CECR7 Gene

Paralogs for CECR7 Gene

No data available for Paralogs for CECR7 Gene

Variants for CECR7 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for CECR7 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000078519 -- 17,049,307(+) A/G intron_variant
rs1000352914 -- 17,043,266(+) T/C intron_variant
rs1000430883 -- 17,036,870(+) C/G non_coding_transcript_variant
rs1000514091 -- 17,053,691(+) T/A intron_variant
rs1000698662 -- 17,059,133(+) C/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CECR7 Gene

Variant ID Type Subtype PubMed ID
dgv4460n100 CNV gain 25217958
dgv4463n100 CNV gain 25217958
esv3568226 CNV loss 25503493
esv3647204 CNV gain 21293372
nsv1064641 CNV gain 25217958
nsv1067241 CNV loss 25217958

Additional Variant Information for CECR7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CECR7

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CECR7 Gene

Disorders for CECR7 Gene

MalaCards: The human disease database

(3) MalaCards diseases for CECR7 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
hepatocellular carcinoma
  • hcc
cat eye syndrome
  • ces
velocardiofacial syndrome
  • cayler cardiofacial syndrome
- elite association - COSMIC cancer census association via MalaCards
Search CECR7 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for CECR7

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with CECR7: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CECR7 Gene

Publications for CECR7 Gene

  1. Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere. (PMID: 11381032) Footz TK … McDermid HE (Genome research 2001) 2 3 58
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  4. Three duplicons form a novel chimeric transcription unit in the pericentromeric region of chromosome 22q11. (PMID: 12483300) Bridgland L … McDermid HE (Human genetics 2003) 3 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for CECR7 Gene

Sources for CECR7 Gene

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