CECR7 Gene (RNA Gene)

Cat Eye Syndrome Chromosome Region, Candidate 7

GC22P017087
GIFtS:
17
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Aliases for CECR7 Gene

Data sources for CECR7 Gene:

Subcategory (RNA class) for CECR7 Gene

lncRNA

Aliases for CECR7 Gene

External Ids for CECR7 Gene

Previous GeneCards Identifiers for CECR7 Gene

  • GC22P014461
  • GC22P015892
  • GC22U900116
  • GC22P017517
  • GC22P001336
  • GC22P017048
  • GC22P017063
  • GC22P017068
  • GC22P017072

Summaries for CECR7 Gene

GeneCards Summary for CECR7 Gene

CECR7 (Cat Eye Syndrome Chromosome Region, Candidate 7) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with CECR7 include Hepatocellular Carcinoma and Congenital Aphakia.

Additional gene information for CECR7 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CECR7 Gene

Genomics for CECR7 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for CECR7 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH22J017036 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE 277.1 +1.1 1131 3.4 ZFP91 SKIL ZNF316 PRDM10 NFE2 BHLHE40 SMARCA4 CTCF NRF1 EP400 CECR7 IL17RA piR-51863 GAB4
GH22J017084 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 29.7 +49.7 49732 4.6 TBP ZBTB10 BCL11A IKZF1 SMAD5 POLR2A ELF1 NONO ZIC2 THAP11 IL17RA CECR7 ENSG00000273203 ADA2 CECR2 HSALNG0133863 TMEM121B
GH22J017035 Enhancer 0.2 Ensembl 275.9 -1.1 -1108 0.3 CECR7 lnc-GAB4-5 GAB4 IL17RA
GH22J017074 Enhancer 1.1 Ensembl ENCODE dbSUPER 30 +39.9 39932 3.8 TBP CTCF REST ZNF639 NBN MAFF SMC3 RAD21 KLF9 ZNF316 RF00017-3735 RF00017-3736 CECR7 TMEM121B LINC01664 ADA2 CECR3 ENSG00000273203 IL17RA GAB4
GH22J017058 Enhancer 0.8 Ensembl ENCODE 27.8 +21.8 21763 0.7 IKZF1 CTCF REST IRF4 TRIM22 SMC3 RAD21 TEAD3 BCL6 EHMT2 piR-30164 CECR7 ENSG00000273203 piR-51863 IL17RA GAB4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CECR7 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the CECR7 gene promoter:
  • AP-4
  • LCR-F1
  • MyoD
  • Roaz
  • SREBP-1a
  • SREBP-1b
  • SREBP-1c
  • Zic1
  • ZIC2

Genomic Locations for CECR7 Gene

Latest Assembly
chr22:17,036,569-17,060,825
(GRCh38/hg38)
Size:
24,257 bases
Orientation:
Plus strand

Previous Assembly
chr22:17,517,460-17,540,960
(GRCh37/hg19 by Entrez Gene)
Size:
23,501 bases
Orientation:
Plus strand

chr22:17,517,460-17,541,715
(GRCh37/hg19 by Ensembl)
Size:
24,256 bases
Orientation:
Plus strand

Genomic View for CECR7 Gene

Genes around CECR7 on UCSC Golden Path with GeneCards custom track
CECR7 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
CECR7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CECR7 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for CECR7 Gene

Proteins for CECR7 Gene

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  1. Antibodies for research
  2. Protein products for research
  3. Assay products for research

Post-translational modifications for CECR7 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CECR7 Gene

Domains & Families for CECR7 Gene

Gene Families for CECR7 Gene

HGNC:
genes like me logo Genes that share domains with CECR7: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for CECR7 Gene

Function for CECR7 Gene

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  1. Animal Models for research
  2. CRISPR products for research
  3. miRNA products for research
  4. Inhibitory RNAs for research
  5. Clone products for research
  6. Cell Lines for research

Phenotypes From GWAS Catalog for CECR7 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CECR7 Gene

Localization for CECR7 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CECR7 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CECR7 Gene

Pathways & Interactions for CECR7 Gene

PathCards logo

SuperPathways for CECR7 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CECR7 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for CECR7 Gene

Drugs & Compounds for CECR7 Gene

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  1. Drug products for research
No Compound Related Data Available

Transcripts for CECR7 Gene

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  2. miRNA products for research
  3. Inhibitory RNAs for research
  4. Clone products for research

Non-coding RNA (ncRNA) Transcripts from RNAcentral for CECR7 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000CCE07B_9606 lncRNA 4004 1

RefSeq: NR_015352,

URS0000CCDFFB_9606 lncRNA 3942 1

RefSeq: NR_152825,

URS0000CCE10D_9606 lncRNA 3560 1

RefSeq: NR_152826,

URS00008C0DAD_9606 lncRNA 385 3

LncBook: HSALNT0275004,

LNCipedia: lnc-IL17RA-33:8,

NONCODE: NONHSAT083177.2,

URS00008C2ABB_9606 lncRNA 280 3

LncBook: HSALNT0275003,

LNCipedia: lnc-IL17RA-33:7,

NONCODE: NONHSAT083176.2,

CECR7 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for CECR7 Gene

6 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR products for research

Alternative Splicing Database (ASD) splice patterns (SP) for CECR7 Gene

No ASD Table

Relevant External Links for CECR7 Gene

GeneLoc Exon Structure for
CECR7

Expression for CECR7 Gene

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  2. Gene Expression Assays for research

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CECR7 Gene

mRNA expression in normal human tissues for CECR7 Gene
mRNA expression by GTEx for CECR7 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CECR7

SOURCE GeneReport for Unigene cluster for CECR7 Gene:

Hs.660640
genes like me logo Genes that share expression patterns with CECR7: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CECR7 Gene

Orthologs for CECR7 Gene

Evolution for CECR7 Gene

ENSEMBL:
Gene Tree for CECR7 (if available)
TreeFam:
Gene Tree for CECR7 (if available)

No data available for Orthologs for CECR7 Gene

Paralogs for CECR7 Gene

No data available for Paralogs for CECR7 Gene

Variants for CECR7 Gene

Products:

  1. SNP Genotyping and Copy Number Assays for research

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for CECR7 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for CECR7 Gene

Variant ID Type Subtype PubMed ID
dgv4460n100 CNV gain 25217958
dgv4463n100 CNV gain 25217958
esv3568226 CNV loss 25503493
esv3647204 CNV gain 21293372
nsv1064641 CNV gain 25217958
nsv1067241 CNV loss 25217958

Additional Variant Information for CECR7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CECR7

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for CECR7 Gene

Disorders for CECR7 Gene

MalaCards: The human disease database

(3) MalaCards diseases for CECR7 Gene - From: LNC and COP

Disorder Aliases PubMed IDs
hepatocellular carcinoma
  • hcc
congenital aphakia
  • aphakia, congenital primary
total anomalous pulmonary venous return 1
  • tapvr1
- elite association - COSMIC cancer census association via MalaCards
Search CECR7 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for CECR7

Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with CECR7: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CECR7 Gene

Publications for CECR7 Gene

  1. Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere. (PMID: 11381032) Footz TK … McDermid HE (Genome research 2001) 2 3
  2. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. (PMID: 28611215) Fei T … Brown M (Proceedings of the National Academy of Sciences of the United States of America 2017) 3
  3. Cancer Specific Long Noncoding RNAs Show Differential Expression Patterns and Competing Endogenous RNA Potential in Hepatocellular Carcinoma. (PMID: 26492393) Zhang J … Lai PB (PloS one 2015) 74
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3

ExternalLinks

View latest publications for CECR7 gene in Mastermind

Products for CECR7 Gene

Sources for CECR7 Gene