Aliases for CEACAM8 Gene
External Ids for CEACAM8 Gene
Previous HGNC Symbols for CEACAM8 Gene
Previous GeneCards Identifiers for CEACAM8 Gene
GeneCards Summary for CEACAM8 Gene
CEACAM8 (CEA Cell Adhesion Molecule 8) is a Protein Coding gene. Diseases associated with CEACAM8 include Hemoglobinuria and Paroxysmal Nocturnal Hemoglobinuria. Among its related pathways are Degradation of the extracellular matrix and Cell surface interactions at the vascular wall. An important paralog of this gene is CEACAM6.
UniProtKB/Swiss-Prot Summary for CEACAM8 Gene
Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:8776764, PubMed:2022629, PubMed:11590190). Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:8776764, PubMed:2022629, PubMed:11590190). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764).