Aliases for CEACAM5 Gene
External Ids for CEACAM5 Gene
Previous HGNC Symbols for CEACAM5 Gene
Previous GeneCards Identifiers for CEACAM5 Gene
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
GeneCards Summary for CEACAM5 Gene
CEACAM5 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 5) is a Protein Coding gene. Diseases associated with CEACAM5 include Lung Cancer and Rectal Neoplasm. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and GPI anchor binding. An important paralog of this gene is CEACAM1.
UniProtKB/Swiss-Prot for CEACAM5 Gene
Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.