Aliases for CDY2A Gene
External Ids for CDY2A Gene
Previous HGNC Symbols for CDY2A Gene
Previous GeneCards Identifiers for CDY2A Gene
This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. [provided by RefSeq, Jul 2008]
GeneCards Summary for CDY2A Gene
CDY2A (Chromodomain Y-Linked 2A) is a Protein Coding gene. Diseases associated with CDY2A include Spermatogenic Failure, Y-Linked, 2 and Y Chromosome Infertility. Gene Ontology (GO) annotations related to this gene include histone acetyltransferase activity. An important paralog of this gene is CDY2B.
UniProtKB/Swiss-Prot Summary for CDY2A Gene
May have histone acetyltransferase activity.