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Aliases for CDRT15L2 Gene

Aliases for CDRT15L2 Gene

  • CMT1A Duplicated Region Transcript 15 Like 2 2 3 5
  • CMT1A Duplicated Region Transcript 15 Protein-Like Protein 3

External Ids for CDRT15L2 Gene

Previous GeneCards Identifiers for CDRT15L2 Gene

  • GC17P020424
  • GC17P020481
  • GC17P019685
  • GC17P020485
  • GC17P020726
  • GC17P021208
  • GC17P021467
  • GC17P021896
  • GC17P020944
  • GC17P021682
  • GC17P022498
  • GC17P022888
  • GC17P023176
  • GC17P023468
  • GC17P023766
  • GC17P024065

Summaries for CDRT15L2 Gene

GeneCards Summary for CDRT15L2 Gene

CDRT15L2 (CMT1A Duplicated Region Transcript 15 Like 2) is a Protein Coding gene. An important paralog of this gene is CDRT15.

Additional gene information for CDRT15L2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDRT15L2 Gene

Genomics for CDRT15L2 Gene

GeneHancer (GH) Regulatory Elements for CDRT15L2 Gene

Top Transcription factor binding sites by QIAGEN in the CDRT15L2 gene promoter:
  • PPAR-gamma2
  • PPAR-gamma1
  • SRF (504 AA)
  • SRF
  • CREB
  • deltaCREB
  • AhR
  • Arnt
  • AML1a

Genomic Locations for CDRT15L2 Gene

Genomic Locations for CDRT15L2 Gene
1,188 bases
Plus strand
1,188 bases
Plus strand

Genomic View for CDRT15L2 Gene

Genes around CDRT15L2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CDRT15L2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CDRT15L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CDRT15L2 Gene

Proteins for CDRT15L2 Gene

  • Protein details for CDRT15L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    CMT1A duplicated region transcript 15 protein-like protein
    Protein Accession:

    Protein attributes for CDRT15L2 Gene

    281 amino acids
    Molecular mass:
    30100 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CDRT15L2 Gene

Post-translational modifications for CDRT15L2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CDRT15L2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CDRT15L2 Gene

Domains & Families for CDRT15L2 Gene

Gene Families for CDRT15L2 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for CDRT15L2 Gene


Suggested Antigen Peptide Sequences for CDRT15L2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CDRT15L2: view

No data available for UniProtKB/Swiss-Prot for CDRT15L2 Gene

Function for CDRT15L2 Gene

Phenotypes for CDRT15L2 Gene

genes like me logo Genes that share phenotypes with CDRT15L2: view

Animal Model Products

miRNA for CDRT15L2 Gene

miRTarBase miRNAs that target CDRT15L2

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CDRT15L2 Gene

Localization for CDRT15L2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CDRT15L2 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CDRT15L2 gene
Compartment Confidence
mitochondrion 2
plasma membrane 1
nucleus 1
endoplasmic reticulum 1
cytosol 1

Gene Ontology (GO) - Cellular Components for CDRT15L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CDRT15L2: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for CDRT15L2 Gene

Pathways & Interactions for CDRT15L2 Gene

SuperPathways for CDRT15L2 Gene

No Data Available

Interacting Proteins for CDRT15L2 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: A8MXV6-CD15L_HUMAN ENSP00000382000 for CDRT15L2 Gene via IID STRING

Gene Ontology (GO) - Biological Process for CDRT15L2 Gene


No data available for Pathways by source and SIGNOR curated interactions for CDRT15L2 Gene

Drugs & Compounds for CDRT15L2 Gene

No Compound Related Data Available

Transcripts for CDRT15L2 Gene

mRNA/cDNA for CDRT15L2 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CDRT15L2 Gene

CMT1A duplicated region transcript 15-like 2:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CDRT15L2 Gene

No ASD Table

Relevant External Links for CDRT15L2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CDRT15L2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CDRT15L2 Gene

mRNA differential expression in normal tissues according to GTEx for CDRT15L2 Gene

This gene is overexpressed in Testis (x43.7) and Brain - Hippocampus (x7.5).

Protein differential expression in normal tissues from HIPED for CDRT15L2 Gene

This gene is overexpressed in Islet of Langerhans (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CDRT15L2 Gene

Protein tissue co-expression partners for CDRT15L2 Gene

NURSA nuclear receptor signaling pathways regulating expression of CDRT15L2 Gene:


SOURCE GeneReport for Unigene cluster for CDRT15L2 Gene:

genes like me logo Genes that share expression patterns with CDRT15L2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CDRT15L2 Gene

Orthologs for CDRT15L2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for CDRT15L2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC455056 33
  • 97.51 (n)
-- 34
  • 94 (a)
-- 34
  • 94 (a)
Species where no ortholog for CDRT15L2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CDRT15L2 Gene

Gene Tree for CDRT15L2 (if available)
Gene Tree for CDRT15L2 (if available)
Evolutionary constrained regions (ECRs) for CDRT15L2: view image

Paralogs for CDRT15L2 Gene

Variants for CDRT15L2 Gene

Sequence variations from dbSNP and Humsavar for CDRT15L2 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000880775 -- 20,579,452(+) T/A upstream_transcript_variant
rs1000973427 -- 20,579,214(+) G/A upstream_transcript_variant
rs1001793683 -- 20,578,013(+) C/T upstream_transcript_variant
rs1002396590 -- 20,579,981(+) C/T coding_sequence_variant, missense_variant
rs1003343407 -- 20,581,288(+) C/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CDRT15L2 Gene

Variant ID Type Subtype PubMed ID
dgv3121n100 CNV loss 25217958
esv23447 CNV gain+loss 19812545
esv2751619 CNV gain 17911159
esv2758680 CNV gain 17122850
esv3572487 CNV gain 25503493
esv3640207 CNV loss 21293372
esv3640208 CNV gain 21293372
nsv1059504 CNV gain 25217958
nsv457705 CNV loss 19166990
nsv510703 CNV deletion 20534489
nsv520772 CNV loss 19592680
nsv521025 CNV gain 19592680
nsv574581 CNV loss 21841781
nsv574596 CNV loss 21841781
nsv833399 CNV loss 17160897
nsv978389 CNV duplication 23825009

Variation tolerance for CDRT15L2 Gene

Gene Damage Index Score: 1.21; 24.35% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CDRT15L2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDRT15L2 Gene

Disorders for CDRT15L2 Gene

Additional Disease Information for CDRT15L2

No disorders were found for CDRT15L2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CDRT15L2 Gene

Publications for CDRT15L2 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 3 4 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58

Products for CDRT15L2 Gene

  • Biorbyt antibodies for CDRT15L2

Sources for CDRT15L2 Gene

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