Aliases for CDKN2C Gene
Aliases for CDKN2C Gene
External Ids for CDKN2C Gene
- HGNC: 1789
- Entrez Gene: 1031
- Ensembl: ENSG00000123080
- OMIM: 603369
- UniProtKB: P42773
Previous GeneCards Identifiers for CDKN2C Gene
- GC01P051060
- GC01P050315
- GC01P050784
- GC01P050796
- GC01P051138
- GC01P051427
- GC01P049551
Summaries for CDKN2C Gene
-
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
GeneCards Summary for CDKN2C Gene
CDKN2C (Cyclin Dependent Kinase Inhibitor 2C) is a Protein Coding gene. Diseases associated with CDKN2C include Choriocarcinoma Of The Testis and Oligodendroglioma. Among its related pathways are Cell Cycle, Mitotic and Mitotic G1-G1/S phases. Gene Ontology (GO) annotations related to this gene include protein kinase binding and cyclin-dependent protein serine/threonine kinase inhibitor activity. An important paralog of this gene is CDKN2D.
UniProtKB/Swiss-Prot for CDKN2C Gene
-
Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
Additional gene information for CDKN2C Gene
- Monarch Initiative
- Search for CDKN2C at DataMed
- Search for CDKN2C at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDKN2C Gene
Genomics for CDKN2C Gene
GeneHancer (GH) Regulatory Elements for CDKN2C Gene
Promoters and enhancers for CDKN2C Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around CDKN2C on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CDKN2C gene promoter:
-
- GR
- GR-alpha
- GATA-1
Regulatory Element Products
Genomic Locations for CDKN2C Gene
Genomic Locations for CDKN2C Gene
- chr1:50,960,745-50,974,637
- (GRCh38/hg38)
- Size:
- 13,893 bases
- Orientation:
- Plus strand
- chr1:51,426,417-51,440,309
- (GRCh37/hg19)
- Size:
- 13,893 bases
- Orientation:
- Plus strand
Genomic View for CDKN2C Gene
Genes around CDKN2C on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p32.3 by Entrez Gene
- 1p32.3 by HGNC
- 1p32.3 by Ensembl
CDKN2C Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CDKN2C Gene
Proteins for CDKN2C Gene
-
Protein details for CDKN2C Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P42773-CDN2C_HUMAN
- Recommended name:
- Cyclin-dependent kinase 4 inhibitor C
- Protein Accession:
- P42773
- Q8TB83
Protein attributes for CDKN2C Gene
- Size:
- 168 amino acids
- Molecular mass:
- 18127 Da
- Quaternary structure:
-
- Heterodimer of p18 with CDK6.
Protein Expression for CDKN2C Gene
Post-translational modifications for CDKN2C Gene
Other Protein References for CDKN2C Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CDKN2C (p18INK4c/CDKN2C)
- Novus Biologicals Antibodies for CDKN2C
-
Abcam antibodies for CDKN2C
- Invitrogen Antibodies for CDKN2C
- antibodies-online: Search results for 101 available CDKN2C Antibodies ranked by validation data
- Compare Top CDKN2C Antibodies
-
Recommended
- 72 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 4 IHC Antibodies (anti-human)
- 2 ICC Antibodies (anti-human)
- 16 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-rat)
- 7 WB Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
- GeneTex CDKN2C Antibody for CDKN2C
-
Boster Bio Antibodies for CDKN2C
-
Santa Cruz Biotechnology (SCBT) Antibodies for CDKN2C
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for CDKN2C
- Origene Custom Protein Services for CDKN2C
- ProSpec Recombinant Proteins for CDKN2C
- GeneTex Proteins for CDKN2C
-
ProSci Proteins for CDKN2C
-
Abcam proteins for CDKN2C
Assay Products
No data available for DME Specific Peptides for CDKN2C Gene
Domains & Families for CDKN2C Gene
Gene Families for CDKN2C Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for CDKN2C Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CDKN2C Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P42773- Family:
-
- Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
Function for CDKN2C Gene
Molecular function for CDKN2C Gene
- UniProtKB/Swiss-Prot Function:
- Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
- GENATLAS Biochemistry:
- cyclin dependent kinase 6 (CDK6),inhibitor p18,regulator of cell cycle,passage through the G1 checkpoint,altered in a low fraction of oligodendroglial tumors
Phenotypes From GWAS Catalog for CDKN2C Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity | IDA | 8001816 |
| GO:0005515 | protein binding | IPI | 8840966 |
| GO:0016301 | kinase activity | IEA | -- |
| GO:0019901 | protein kinase binding | IPI | 8001816 |
Phenotypes for CDKN2C Gene
- MGI mutant phenotypes for CDKN2C:
-
inferred from 2 alleles
- cardiovascular system phenotype
- respiratory system phenotype
- homeostasis/metabolism phenotype
- nervous system phenotype
- behavior/neurological phenotype
- neoplasm
- integument phenotype
- endocrine/exocrine gland phenotype
- mortality/aging
- cellular phenotype
- reproductive system phenotype
- renal/urinary system phenotype
- hematopoietic system phenotype
- immune system phenotype
- growth/size/body region phenotype
- GenomeRNAi human phenotypes for CDKN2C:
-
- Decreased viability in esophageal squamous lineage
- Increased Nanog expression
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Paclitaxel antagonistic effect
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Mildly decreased CFP-tsO45G cell surface transport
- Strongly decreased CFP-tsO45G cell surface transport
- Increased transferrin (TF) endocytosis
Animal Models for CDKN2C Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CDKN2C
-
CRISPR Products
-
OriGene CRISPR knockouts for CDKN2C
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CDKN2C
- genomics-online: gRNA clones - Search results for 85 available CDKN2C gene related products
- Overview of 85 available CDKN2C gene related products
- Applied Biological Materials CRISPR for CDKN2C
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDKN2C
- GenScript: Design CRISPR guide RNA sequences for CDKN2C
miRNA for CDKN2C Gene
- miRTarBase miRNAs that target CDKN2C
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CDKN2C
- Browse OriGene Inhibitory RNA Products For CDKN2C
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CDKN2C
- genomics-online: shRNA clones - Search results for 85 available CDKN2C gene related products
- Overview of 85 available CDKN2C gene related products
Clone Products
- Sino Biological Human cDNA Clone for CDKN2C
- VectorBuilder custom plasmid, inducible vectors for CDKN2C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDKN2C
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CDKN2C
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CDKN2C
- Applied Biological Materials Clones for CDKN2C
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CDKN2C
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for CDKN2C Gene
Localization for CDKN2C Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | 11800646 |
| GO:0005737 | cytoplasm | IDA | 11800646 |
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for CDKN2C Gene
Pathways & Interactions for CDKN2C Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cyclins and Cell Cycle Regulation |
.31
|
|
| 2 | Cellular Senescence (REACTOME) | ||
| 3 | Glioma | ||
| 4 | Cell Cycle, Mitotic |
.83
|
|
| 5 | Mitotic G1-G1/S phases | ||
Pathways by source for CDKN2C Gene
1 GeneTex pathway for CDKN2C Gene
3 BioSystems pathways for CDKN2C Gene
10 Reactome pathways for CDKN2C Gene
5 KEGG pathways for CDKN2C Gene
4 Qiagen pathways for CDKN2C Gene
1 Cell Signaling Technology pathway for CDKN2C Gene
Interacting Proteins for CDKN2C Gene
Selected Interacting proteins:
P42773-CDN2C_HUMAN
ENSP00000262662
for CDKN2C Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for CDKN2C
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | IDA | 8001816 |
| GO:0000082 | G1/S transition of mitotic cell cycle | IDA | 10208428 |
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007050 | cell cycle arrest | IDA | 10208428 |
| GO:0008285 | negative regulation of cell proliferation | IDA | 10208428 |
Drugs & Compounds for CDKN2C Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| AT7519 | Investigational | Pharma | Multi-CDK inhibitor | 0 | ||
| Kenpaullone | Pharma | 0 | ||||
| ML167 | Pharma | Clk4 inhibitor,highly selective | 0 | |||
| Nu 6027 | Pharma | ATR/CDK inhibitor, potent and selective | 0 | |||
| PHA-848125 | Pharma | CDK inhibitor,potent and ATP-competitive | 0 |
(8) ApexBio Compounds for CDKN2C Gene
| Compound | Action | Cas Number |
|---|---|---|
| AT7519 | Multi-CDK inhibitor | 844442-38-2 |
| Kenpaullone | 142273-20-9 | |
| ML167 | Clk4 inhibitor,highly selective | 1285702-20-6 |
| Nu 6027 | ATR/CDK inhibitor, potent and selective | 220036-08-8 |
| PHA-848125 | CDK inhibitor,potent and ATP-competitive | 802539-81-7 |
| Purvalanol B | CDK1/CDK2/CDK4 inhibitor | 212844-54-7 |
| R547 | CDK1/2/4 inhibitor,ATP-competitive | 741713-40-6 |
| Ro 3306 | An ATP-competitive, potent CDK1 inhibitor | 872573-93-8 |
Transcripts for CDKN2C Gene
mRNA/cDNA for CDKN2C Gene
- (2) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (156) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000262662 2904 bps (uc057gkh.1)
- ENST00000371761 1220 bps (uc001csg.4)
- ENST00000396148 2086 bps (uc001csf.4)
Unigene Clusters for CDKN2C Gene
CRISPR Products
-
OriGene CRISPR knockouts for CDKN2C
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CDKN2C
- genomics-online: gRNA clones - Search results for 85 available CDKN2C gene related products
- Overview of 85 available CDKN2C gene related products
- Applied Biological Materials CRISPR for CDKN2C
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDKN2C
- GenScript: Design CRISPR guide RNA sequences for CDKN2C
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CDKN2C
- Browse OriGene Inhibitory RNA Products For CDKN2C
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CDKN2C
- genomics-online: shRNA clones - Search results for 85 available CDKN2C gene related products
- Overview of 85 available CDKN2C gene related products
Clone Products
- Sino Biological Human cDNA Clone for CDKN2C
- VectorBuilder custom plasmid, inducible vectors for CDKN2C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDKN2C
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CDKN2C
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CDKN2C
- Applied Biological Materials Clones for CDKN2C
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for CDKN2C Gene
This gene is overexpressed in Ovary (22.9) and Uterus (6.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CDKN2C Gene
NURSA nuclear receptor signaling pathways regulating expression of CDKN2C Gene:
CDKN2CSOURCE GeneReport for Unigene cluster for CDKN2C Gene:
Hs.525324mRNA Expression by UniProt/SwissProt for CDKN2C Gene:
P42773-CDN2C_HUMAN
Tissue specificity:
Highest levels found in skeletal muscle. Also found in pancreas and heart.
Evidence on tissue expression from TISSUES for CDKN2C Gene
- Nervous system(4.8)
- Kidney(4.2)
- Bone marrow(2.3)
Phenotype-based relationships between genes and organs from Gene ORGANizer for CDKN2C Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- endocrine
- immune
- integumentary
- lymphatic
- nervous
- reproductive
- skeletal muscle
- skeleton
- urinary
Regions:
Head and neck:
- brain
- ear
- eye
- face
- head
- jaw
- mandible
- maxilla
- mouth
- neck
- parathyroid
- pituitary gland
- skull
- thyroid
Thorax:
- chest wall
- clavicle
- esophagus
- heart
- lung
- rib
- rib cage
- scapula
- sternum
Abdomen:
- adrenal gland
- gallbladder
- intestine
- kidney
- large intestine
- liver
- pancreas
- small intestine
- stomach
Pelvis:
- ovary
- pelvis
- uterus
Limb:
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
General:
- blood
- blood vessel
- lymph node
- peripheral nerve
- peripheral nervous system
- skin
- spinal column
- sweat gland
- vertebrae
- white blood cell
Primer Products
-
OriGene qPCR primer pairs and template standards for CDKN2C
-
OriGene qPCR primer pairs for CDKN2C
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Protein tissue co-expression partners for CDKN2C Gene
Orthologs for CDKN2C Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CDKN2C 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | CDKN2C 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | CDKN2C 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Cdkn2c 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cdkn2c 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CDKN2C 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CDKN2C 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | CDKN2C 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cdkn2c 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | cdkn2c 34 33 |
|
OneToOne |
- Species where no ortholog for CDKN2C was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for CDKN2C Gene
- ENSEMBL:
- Gene Tree for CDKN2C (if available)
- TreeFam:
- Gene Tree for CDKN2C (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CDKN2C: view image
Paralogs for CDKN2C Gene
(40) SIMAP similar genes for CDKN2C Gene using alignment to 3 proteins:
- CDN2C_HUMAN
- Q6ICV4_HUMAN
- Q9P1T2_HUMAN
Variants for CDKN2C Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| VAR_001490 | Breast cancer | p.Ala72Pro | |||
| rs1000741886 | -- | 50,971,795(+) | T/C | intron_variant | |
| rs1001048828 | -- | 50,971,209(+) | C/T | intron_variant | |
| rs1001143288 | -- | 50,971,584(+) | A/G | intron_variant | |
| rs1001387016 | -- | 50,969,451(+) | C/G/T | 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1004803 | CNV | gain | 25217958 |
| nsv546205 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
48.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.85;
17.77% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CDKN2C Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDKN2C Gene
Disorders for CDKN2C Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| choriocarcinoma of the testis |
|
|
| oligodendroglioma |
|
|
| multiple endocrine neoplasia, type i |
|
|
| anaplastic oligodendroglioma |
|
|
| parathyroid adenoma |
|
Search CDKN2C in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CDKN2C
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for CDKN2C Gene
Publications for CDKN2C Gene
- Structure of the gene encoding the human cyclin-dependent kinase inhibitor p18 and mutational analysis in breast cancer. (PMID: 9636670) Blais A … Labrie C (Biochemical and biophysical research communications 1998) 2 3 4 22 58
- Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. (PMID: 8001816) Guan KL … Xiong Y (Genes & development 1994) 2 3 4 22 58
- Rare germline mutations in cyclin-dependent kinase inhibitor genes in multiple endocrine neoplasia type 1 and related states. (PMID: 19141585) Agarwal SK … Marx SJ (The Journal of clinical endocrinology and metabolism 2009) 3 22 44 58
- Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population. (PMID: 18174243) Driver KE … Studies in Epidemiology and Risks of Cancer Heredity (SEARCH) Team (Carcinogenesis 2008) 3 22 44 58
- Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort. (PMID: 18507837) Azzato EM … Pharoah PD (Breast cancer research : BCR 2008) 3 22 44 58
Products for CDKN2C Gene
- R&D Systems Antibodies for CDKN2C (p18INK4c/CDKN2C)
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- Abcam antibodies for CDKN2C
- Abcam proteins for CDKN2C
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- ProSpec Recombinant Proteins for CDKN2C
- Cyagen custom Knockout/knockin (KOKI) mouse models for CDKN2C
- VectorBuilder custom plasmid, inducible vectors for CDKN2C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDKN2C
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CDKN2C
- antibodies-online: Search results for 101 available CDKN2C Antibodies ranked by validation data
- Compare Top CDKN2C Antibodies
- Recommended
- 72 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 4 IHC Antibodies (anti-human)
- 2 ICC Antibodies (anti-human)
- 16 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-rat)
- 7 WB Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
- antibodies-online: Search results for 6 available CDKN2C Elisa Kits ranked by validation data
- Compare Top CDKN2C Elisa Kits
- Recommended
- antibodies-online: Search results for 11 available CDKN2C Proteins ranked by validation data
- Compare Top CDKN2C Proteins
- GeneTex CDKN2C Antibody for CDKN2C
- GeneTex Proteins for CDKN2C
- Santa Cruz Biotechnology (SCBT) Antibodies for CDKN2C
- Search Santa Cruz Biotechnology (SCBT) for CDKN2C siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CDKN2C
- Search for CDKN2C Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for CDKN2C
- Horizon Cell Lines for CDKN2C
- genomics-online: cdna clones - Search results for 85 available CDKN2C gene related products
- Overview of 85 available CDKN2C gene related products
- orf clones - Search results for 85 available CDKN2C gene related products
- Overview of 85 available CDKN2C gene related products
- genomics-online: gRNA clones - Search results for 85 available CDKN2C gene related products
- Overview of 85 available CDKN2C gene related products
- genomics-online: primer clones - Search results for 85 available CDKN2C gene related products
- Overview of 85 available CDKN2C gene related products
- genomics-online: shRNA clones - Search results for 85 available CDKN2C gene related products
- Overview of 85 available CDKN2C gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CDKN2C
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CDKN2C
- GeneCopoeia miRNA 3'UTR Target clone products for CDKN2C
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CDKN2C
- Boster Bio Antibodies for CDKN2C
- Browse Boster Bio ELISA Kits
Sources for CDKN2C Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt