This gene is located within the CDKN2B-CDKN2A gene cluster at chromosome 9p21. The gene product is a functional RNA molecule that interacts with polycomb repressive complex-1 (PRC1) and -2 (PRC2), leading to epigenetic silencing of other genes in this cluster. This region is a significant genetic susceptibility locus for cardiovascular disease, and has also been linked to a num...
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Aliases for CDKN2B-AS1 Gene
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CDKN2B Antisense RNA 1
2
3
5
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CDKN2B-AS1 2
170
171
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Prostate Cancer Associated Transcript 12 2
3
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P15 Antisense RNA 2
3
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CDKN2B Antisense RNA 1 (Non-Protein Coding) 3
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Antisense Noncoding RNA In The INK4 Locus 3
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CDKN2B Antisense RNA (Non-Protein Coding) 2
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Antisense RNA In The INK4 Locus 2
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Non-Protein Coding RNA 89 2
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HSALNG0070397 169
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NONHSAG051899 94
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NCRNA00089 3
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CDKN2B-AS 3
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CDKN2BAS 3
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PCAT12 3
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ANRIL 3
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P15AS 3
External Ids for CDKN2B-AS1 Gene
Previous HGNC Symbols for CDKN2B-AS1 Gene
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This gene is located within the CDKN2B-CDKN2A gene cluster at chromosome 9p21. The gene product is a functional RNA molecule that interacts with polycomb repressive complex-1 (PRC1) and -2 (PRC2), leading to epigenetic silencing of other genes in this cluster. This region is a significant genetic susceptibility locus for cardiovascular disease, and has also been linked to a number of other pathologies, including several cancers, intracranial aneurysm, type-2 diabetes, periodontitis, Alzheimer's disease, endometriosis, frailty in the elderly, and glaucoma. Multiple alternatively processed transcript variants have been detected, some of which may take the form of circular RNA molecules (PMID:21151960). [provided by RefSeq, May 2014]
CDKN2B-AS1 (CDKN2B Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class.
Diseases associated with CDKN2B-AS1 include Intracranial Aneurysm and Periodontitis.
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CDKN2B antisense RNA 1 convserved region 3
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CDKN2B antisense RNA 1 convserved region 2
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CDKN2B antisense RNA 1 intronic convserved region
No data available for
CIViC Summary ,
UniProtKB/Swiss-Prot Summary ,
Tocris Summary ,
PharmGKB "VIP" Summary and
piRNA Summary
for CDKN2B-AS1 Gene