Aliases for CDK5RAP1 Gene
External Ids for CDK5RAP1 Gene
Previous HGNC Symbols for CDK5RAP1 Gene
Previous GeneCards Identifiers for CDK5RAP1 Gene
This gene encodes a regulator of cyclin-dependent kinase 5 activity. This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013]
GeneCards Summary for CDK5RAP1 Gene
CDK5RAP1 (CDK5 Regulatory Subunit Associated Protein 1) is a Protein Coding gene. Diseases associated with CDK5RAP1 include Chorea Gravidarum and Inflammatory Bowel Disease 17. Gene Ontology (GO) annotations related to this gene include protein kinase binding and transferase activity. An important paralog of this gene is CDKAL1.
UniProtKB/Swiss-Prot Summary for CDK5RAP1 Gene
Specifically inhibits CDK5 activation by CDK5R1.