Aliases for CDK5R2 Gene
External Ids for CDK5R2 Gene
Previous GeneCards Identifiers for CDK5R2 Gene
The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008]
GeneCards Summary for CDK5R2 Gene
CDK5R2 (Cyclin Dependent Kinase 5 Regulatory Subunit 2) is a Protein Coding gene. Diseases associated with CDK5R2 include Bardet-Biedl Syndrome 9. Among its related pathways are Lissencephaly gene (LIS1) in neuronal migration and development and Reelin Pathway (Cajal-Retzius cells). Gene Ontology (GO) annotations related to this gene include lipid binding and cyclin-dependent protein kinase 5 activator activity. An important paralog of this gene is CDK5R1.
UniProtKB/Swiss-Prot Summary for CDK5R2 Gene
Activator of CDK5/TPKII.