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The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jul 2010] See more...
Aliases for CDK17 Gene
Aliases for CDK17 Gene
External Ids for CDK17 Gene
- HGNC: 8750
- NCBI Entrez Gene: 5128
- Ensembl: ENSG00000059758
- OMIM®: 603440
- UniProtKB/Swiss-Prot: Q00537
Previous HGNC Symbols for CDK17 Gene
- PCTK2
Previous GeneCards Identifiers for CDK17 Gene
- GC12M095196
- GC12M096673
- GC12M093733
Summaries for CDK17 Gene
-
The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jul 2010]
GeneCards Summary for CDK17 Gene
CDK17 (Cyclin Dependent Kinase 17) is a Protein Coding gene. Diseases associated with CDK17 include Corneal Dystrophy, Posterior Amorphous. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDK16.
UniProtKB/Swiss-Prot Summary for CDK17 Gene
-
May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity).
Additional gene information for CDK17 Gene
- HGNC (8750)
- NCBI Entrez Gene (5128)
- Ensembl (ENSG00000059758)
- OMIM® (603440)
- UniProtKB/Swiss-Prot (Q00537)
- Open Targets Platform(ENSG00000059758)
- Search for CDK17 at DataMed
- Search for CDK17 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CDK17 Gene
Genomics for CDK17 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CDK17 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CDK17 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CDK17
Genomic Locations for CDK17 Gene
Latest Assembly
- chr12:96,278,225-96,400,480
- (GRCh38/hg38)
- Size:
- 122,256 bases
- Orientation:
- Minus strand
Previous Assembly
- chr12:96,672,003-96,794,217
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 122,215 bases
- Orientation:
- Minus strand
- chr12:96,672,039-96,794,338
- (GRCh37/hg19 by Ensembl)
- Size:
- 122,300 bases
- Orientation:
- Minus strand
Genomic View for CDK17 Gene
Genes around CDK17 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q23.1 by HGNC
- 12q23.1 by Entrez Gene
- 12q23.1 by Ensembl
CDK17 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CDK17 Gene
Proteins for CDK17 Gene
-
Protein details for CDK17 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q00537-CDK17_HUMAN
- Recommended name:
- Cyclin-dependent kinase 17
- Protein Accession:
- Q00537
- A8K1U6
- B2RCQ2
- Q8NEB8
Protein attributes for CDK17 Gene
- Size:
- 523 amino acids
- Molecular mass:
- 59582 Da
- Quaternary structure:
-
- Found in a complex containing CABLES1, CDK16 and TDRD7. Interacts with TDRD7 (By similarity).
Protein Expression for CDK17 Gene
Selected DME Specific Peptides for CDK17 Gene
- Q00537:
-
- PQPLINHAPRLD
- LEKLGEG
- IFRLLGTP
- GELKLADFGLA
- DFGLARA
- LKHANIV
- LRGLAYCH
- SIFSLKEIQLQKDPG
- VVTLWYR
- LADFGLA
- KLGEGTYATV
- VLHRDLK
- GRPLFPGS
- GRPLFPG
- HRDLKPQN
- FKRRLSL
- PDVLLGS
- SMEDLNKRLSLP
Post-translational modifications for CDK17 Gene
Other Protein References for CDK17 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- G Biosciences Immunotag™ PCTK2 Antibody
-
Custom Antibody ServicesOriGene Antibodies for CDK17
- Novus Biologicals Antibodies for CDK17
-
Abcam antibodies for CDK17
- Invitrogen Antibodies for CDK17 (AFLGC-CDK17)
-
Boster Bio Antibodies for CDK17
-
Custom Antibody ServicesProSci Antibodies for CDK17
Protein products for research
-
OriGene Purified Proteins for CDK17
- Search Origene for MassSpec and Protein Over-expression Lysates for CDK17
- Origene Custom Protein Services for CDK17
- antibodies-online: Show 7 available CDK17 Proteins ranked by validation data
- Compare Top CDK17 Proteins
-
Quality Products:
-
Abcam proteins for CDK17
Assay products for research
Domains & Families for CDK17 Gene
Gene Families for CDK17 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for CDK17 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CDK17 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ75213 (A8K1U6_HUMAN)
- Serine/threonine-protein kinase PCTAIRE-2 (CDK17_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q00537UniProtKB/Swiss-Prot:
CDK17_HUMAN :- Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
- Family:
-
- Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Function for CDK17 Gene
Molecular function for CDK17 Gene
- UniProtKB/Swiss-Prot Function:
- May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity).
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.22;.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.22;.
Enzyme Numbers (IUBMB) for CDK17 Gene
Phenotypes From GWAS Catalog for CDK17 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0004672 | protein kinase activity | IEA,TAS | 1639063 |
| GO:0004674 | protein serine/threonine kinase activity | IEA | -- |
| GO:0004693 | cyclin-dependent protein serine/threonine kinase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 15161933 |
Phenotypes for CDK17 Gene
- MGI mutant phenotypes for CDK17:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CDK17:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased viability
- Resistant to vaccinia virus (VACV-A4L) infection
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Decreased substrate adherent cell growth
- Decreased homologous recombination repair frequency
- Increased IL-8 secretion
- Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435)
- Decreased human cytomegalovirus (HCMV) strain AD169 replication
- Increased ionizing radiation sensitivity
- Increased endosome-nucleus distance (endosomes dispersed in the cell periphery)
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for CDK17 - Starting at $85 >
- * CDK17 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for CDK17
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CDK17
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDK17
miRNA for CDK17 Gene
- miRTarBase miRNAs that target CDK17
-
- mmu-miR-15a-5p (MIRT011983)
- hsa-miR-335-5p (MIRT017391)
- hsa-miR-103a-3p (MIRT027115)
- hsa-miR-98-5p (MIRT027559)
- hsa-miR-16-5p (MIRT031589)
- hsa-miR-193b-3p (MIRT041319)
- hsa-miR-374b-3p (MIRT189030)
- hsa-miR-4524b-5p (MIRT548930)
- hsa-miR-4524a-5p (MIRT548931)
- hsa-miR-4645-3p (MIRT548932)
- hsa-miR-145-3p (MIRT548933)
- hsa-miR-1324 (MIRT548934)
- hsa-miR-101-5p (MIRT548935)
- hsa-miR-1244 (MIRT548936)
- hsa-miR-3908 (MIRT548937)
- hsa-miR-646 (MIRT548938)
- hsa-miR-580-5p (MIRT548939)
- hsa-miR-3129-5p (MIRT548940)
- hsa-miR-199a-3p (MIRT548941)
- hsa-miR-199b-3p (MIRT548942)
- hsa-miR-503-5p (MIRT548943)
- hsa-miR-497-5p (MIRT548944)
- hsa-miR-15b-5p (MIRT548945)
- hsa-miR-15a-5p (MIRT548946)
- hsa-miR-6838-5p (MIRT548947)
- hsa-miR-195-5p (MIRT548948)
- hsa-miR-424-5p (MIRT548949)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CDK17
- Browse OriGene Inhibitory RNA Products For CDK17
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CDK17
Clone products for research
- Applied Biological Materials (abm): Clones for CDK17 - Starting at $45 >
- * CDK17 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for CDK17
- Addgene plasmids for CDK17
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CDK17
Cell Lines for research
-
Horizon Cell Lines for CDK17
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CDK17 Gene
Localization for CDK17 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005737 | cytoplasm | IBA | 21873635 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for CDK17 Gene
Pathways & Interactions for CDK17 Gene
Pathways by source for CDK17 Gene
1 GeneTex pathway for CDK17 Gene
Interacting Proteins for CDK17 Gene
Selected Interacting proteins:
Q00537-CDK17_HUMAN
ENSP00000261211
for CDK17 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for CDK17
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle | IBA | 21873635 |
| GO:0006468 | protein phosphorylation | IEA,IBA | 21873635 |
| GO:0016310 | phosphorylation | IEA | -- |
| GO:0051726 | regulation of cell cycle | IEA | -- |
No data available for SIGNOR curated interactions for CDK17 Gene
Drugs & Compounds for CDK17 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| ADP |
|
58-64-0 |
|
Transcripts for CDK17 Gene
mRNA/cDNA for CDK17 Gene
- 2 REFSEQ mRNAs :
- 11 NCBI additional mRNA sequence :
- 12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000261211 4036 nts (view in UCSC)
- ENST00000542666 1769 nts (view in UCSC)
- ENST00000543119 2442 nts (view in UCSC)
- ENST00000548422 892 nts (view in UCSC)
- ENST00000548734 556 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for CDK17 - Starting at $85 >
- * CDK17 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for CDK17
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CDK17
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDK17
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CDK17
- Browse OriGene Inhibitory RNA Products For CDK17
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CDK17
Clone products for research
- Applied Biological Materials (abm): Clones for CDK17 - Starting at $45 >
- * CDK17 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for CDK17
- Addgene plasmids for CDK17
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CDK17
Relevant External Links for CDK17 Gene
- GeneLoc Exon Structure for
- CDK17
Expression for CDK17 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
This gene is overexpressed in Urine (36.2), Amniocyte (9.4), and Placenta (9.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CDK17 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CDK17
SOURCE GeneReport for Unigene cluster for CDK17 Gene:
Hs.506415Evidence on tissue expression from TISSUES for CDK17 Gene
- Nervous system(4.9)
Primer products for research
-
OriGene qPCR primer pairs for CDK17
-
OriGene qPCR primer pairs and template standards for CDK17
Gene Expression Assays for research
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CDK17 Gene
Orthologs for CDK17 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | CDK17 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | CDK17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | CDK17 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | CDK17 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | CDK17 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Cdk17 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Cdk17 30 |
|
||
| Chicken (Gallus gallus) |
Aves | CDK17 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | CDK17 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | cdk17 30 |
|
||
| Str.17214 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | cdk16 31 |
|
OneToOne | |
| LOC798487 30 |
|
||||
| Dr.26649 30 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.10983 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | pct-1 30 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | PHO85 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.10414 31 |
|
OneToMany |
- Species where no ortholog for CDK17 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for CDK17 Gene
- ENSEMBL:
- Gene Tree for CDK17 (if available)
- TreeFam:
- Gene Tree for CDK17 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CDK17: view image
Paralogs for CDK17 Gene
Paralogs for CDK17 Gene
(55) SIMAP similar genes for CDK17 Gene using alignment to 6 proteins:
- CDK17_HUMAN
- F5H6Z0_HUMAN
- F8VQZ9_HUMAN
- F8VUX2_HUMAN
- F8VZY6_HUMAN
- F8W1S5_HUMAN
- PCTK1
- PCTK3
- CDK5
- CDK3
- CDK1
- CDC2
- DKFZp686L20222
- CDK18
- CDK15
- CDK2
- CDK16
- CDK14
- CDK10
- CCRK
- CDK20
- MAPK7
- CDKL1
- CDK7
- CDK11B
- CDK11A
- CDC2L2
- CDC2L1
- CDKL4
- CDK6
- CAMK1
- MAK
- CDK4
- MOK
- MARK4
- CDK9
- PRKAA1
- DKFZp686O0215
- CDKL2
- MAPK1
- STK25
- STK17A
- GSK3A
- DKFZp686D0638
- CDKL3
- MAPK3
- STK36
- NUAK1
- CDK8
- ULK4
- STK11
- RPS6KA2
- MAPK8
- MAPK13
- CDK12
- DKFZp564L2416
- CDK19
- MAPK14
- DKFZp686M02159
- MAPK12
- MAPK11
Variants for CDK17 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CDK17 Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs141560239 | Benign: not provided | 96,297,725(-) |
C/T NM_002595.5(CDK17):c.716-4G>A |
INTRON | |
| rs764448325 | - |
p.Thr214Ile |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2676742 | CNV | deletion | 23128226 |
| esv3424108 | CNV | insertion | 20981092 |
| esv3630450 | CNV | loss | 21293372 |
| nsv1035411 | CNV | gain | 25217958 |
| nsv1149335 | CNV | duplication | 26484159 |
| nsv53730 | CNV | insertion | 16902084 |
| nsv7234 | OTHER | inversion | 18451855 |
| nsv836 | CNV | insertion | 18451855 |
| nsv983492 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
12% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.86;
17.93% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CDK17 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CDK17
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDK17 Gene
Disorders for CDK17 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| corneal dystrophy, posterior amorphous |
|
|
Search CDK17 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CDK17
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for CDK17 Gene
Publications for CDK17 Gene
- Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. (PMID: 22359512) Demirkan A … EUROSPAN consortium (PLoS genetics 2012) 3 41
- Cyclin-dependent kinases: a family portrait. (PMID: 19884882) Malumbres M … Wolgemuth DJ (Nature cell biology 2009) 2 3
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly expressed in terminally differentiated neurons. (PMID: 9370357) Hirose T … Okada M (European journal of biochemistry 1997) 2 3
- A family of human cdc2-related protein kinases. (PMID: 1639063) Meyerson M … Tsai LH (The EMBO journal 1992) 3 4
ExternalLinks
Products for CDK17 Gene
- Custom Antibody ServicesOriGene Antibodies for CDK17
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- Custom Assay Services
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- Search Origene for MassSpec and Protein Over-expression Lysates for CDK17
- Origene Custom Protein Services for CDK17
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CDK17
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- OriGene qPCR primer pairs for CDK17
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- High-throughput Antibody Production Service
- Protein Production Service
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- Novus Biologicals proteins and lysates for CDK17
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- VectorBuilder CRISPR vectors for CDK17 (ie. knockout, knockin, CRISPRa, CRISPRi)
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- VectorBuilder Stable cell line generation for CDK17
- Addgene plasmids for CDK17
- antibodies-online: Show 20 available CDK17 Antibodies ranked by validation data
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- antibodies-online: Search results for available CDK17 related products ranked by validation data
- antibodies-online: Show 7 available CDK17 Proteins ranked by validation data
- Compare Top CDK17 Proteins
- Quality Products:
- Horizon Cell Lines for CDK17
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CDK17
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CDK17
- Search GeneCopoeia for miRNA 3'UTR Target clone products for CDK17
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CDK17
- Boster Bio Antibodies for CDK17
- Browse Boster Bio ELISA Kits
Sources for CDK17 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB