Aliases for CDH6 Gene
External Ids for CDH6 Gene
Previous GeneCards Identifiers for CDH6 Gene
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011]
GeneCards Summary for CDH6 Gene
CDH6 (Cadherin 6) is a Protein Coding gene. Diseases associated with CDH6 include Craniofacial-Deafness-Hand Syndrome and Renal Cell Carcinoma, Nonpapillary. Among its related pathways are Presenilin-Mediated Signaling and Cell junction organization. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH9.
UniProtKB/Swiss-Prot Summary for CDH6 Gene
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.