Aliases for CDCP1 Gene
External Ids for CDCP1 Gene
Previous GeneCards Identifiers for CDCP1 Gene
This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
GeneCards Summary for CDCP1 Gene
CDCP1 (CUB Domain Containing Protein 1) is a Protein Coding gene. Diseases associated with CDCP1 include Ovarian Clear Cell Carcinoma and Colorectal Cancer. Among its related pathways are Adhesion and Wnt / Hedgehog / Notch.
UniProtKB/Swiss-Prot Summary for CDCP1 Gene
May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.