Aliases for CDCA5 Gene
Aliases for CDCA5 Gene
External Ids for CDCA5 Gene
- HGNC: 14626
- Entrez Gene: 113130
- Ensembl: ENSG00000146670
- OMIM: 609374
- UniProtKB: Q96FF9
Previous GeneCards Identifiers for CDCA5 Gene
- GC11U990624
- GC11M065095
- GC11M064620
- GC11M064601
- GC11M064844
- GC11M061171
- GC11M064833
Summaries for CDCA5 Gene
GeneCards Summary for CDCA5 Gene
CDCA5 (Cell Division Cycle Associated 5) is a Protein Coding gene. Diseases associated with CDCA5 include Cornelia De Lange Syndrome. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Cell Cycle, Mitotic. Gene Ontology (GO) annotations related to this gene include chromatin binding.
UniProtKB/Swiss-Prot for CDCA5 Gene
-
Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDCA5 Gene
Genomics for CDCA5 Gene
GeneHancer (GH) Regulatory Elements for CDCA5 Gene
Promoters and enhancers for CDCA5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CDCA5 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CDCA5 gene promoter:
Regulatory Element Products
Genomic Locations for CDCA5 Gene
Genomic Locations for CDCA5 Gene
- chr11:65,061,009-65,084,164
- (GRCh38/hg38)
- Size:
- 23,156 bases
- Orientation:
- Minus strand
- chr11:64,833,772-64,851,636
- (GRCh37/hg19)
Genomic View for CDCA5 Gene
Genes around CDCA5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.1 by Ensembl
- 11q13.1 by Entrez Gene
- 11q13.1 by HGNC
CDCA5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CDCA5 Gene
Proteins for CDCA5 Gene
-
Protein details for CDCA5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96FF9-CDCA5_HUMAN
- Recommended name:
- Sororin
- Protein Accession:
- Q96FF9
- A8K625
Protein attributes for CDCA5 Gene
- Size:
- 252 amino acids
- Molecular mass:
- 27601 Da
- Quaternary structure:
-
- Interacts with the APC/C complex (By similarity). Interacts with the chromatin-bound cohesin complex; the interaction is indirect, occurs after DNA replication and requires acetylation of the cohesin component SMC3. Interacts (via the FGF motif) with PDS5A and PDS5B; the interaction is direct and prevents the interaction of PDS5A with WAPL.
- Miscellaneous:
-
- Named sororin after the Latin word soror, which means sister, because of its critical role in sister chromatid cohesion.
Protein Expression for CDCA5 Gene
Post-translational modifications for CDCA5 Gene
- Phosphorylated. Phosphorylation, as cells enter mitosis, disrupts the interaction with PDS5A and relieves the inhibition of WAPL by CDCA5.
- Ubiquitinated by the APC/C complex in G1, leading to its degradation.
- Ubiquitination at posLast=9999
- Modification sites at PhosphoSitePlus
Other Protein References for CDCA5 Gene
Antibody Products
- Novus Biologicals Antibodies for CDCA5
-
Abcam antibodies for CDCA5
- Invitrogen Antibodies for CDCA5
- GeneTex CDCA5 antibody for CDCA5
-
Santa Cruz Biotechnology (SCBT) Antibodies for CDCA5
Protein Products
-
OriGene Purified Proteins for CDCA5
- Search Origene for MassSpec and Protein Over-expression Lysates for CDCA5
- Origene Custom Protein Services for CDCA5
- Search GeneTex for Proteins for CDCA5
-
Abcam proteins for CDCA5
Assay Products
No data available for DME Specific Peptides for CDCA5 Gene
Domains & Families for CDCA5 Gene
Gene Families for CDCA5 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for CDCA5 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q96FF9UniProtKB/Swiss-Prot:
CDCA5_HUMAN :- The KEN box is required for the association with the APC/C complex.
- Belongs to the sororin family.
- Domain:
-
- The KEN box is required for the association with the APC/C complex.
- Family:
-
- Belongs to the sororin family.
Function for CDCA5 Gene
Molecular function for CDCA5 Gene
- UniProtKB/Swiss-Prot Function:
- Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003682 | chromatin binding | TAS | 15837422 |
| GO:0005515 | protein binding | IPI | 21111234 |
Phenotypes for CDCA5 Gene
- MGI mutant phenotypes for CDCA5:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CDCA5:
-
- Mitotic spindle defects
- Increased viability
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Lamellipodia cells
- Dynamic nuclei (hole, folded or small irregular)
- Decreased NF-kappaB reporter expression
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Increased G1 DNA content
- G0/1 arrest
- Effect on mitosis
- Decreased viability
- Increased number of mitotic cells
- Decreased Salmonella enterica Typhimurium invasion
- Increased cell number in S
- Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435)
- Increased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor)
- Decreased viability of wild-type and TP53 knockout cells
- Multipolar spindles
- Inhibition of centrosomal clustering
Animal Models for CDCA5 Gene
- MGI Knock Outs for CDCA5:
-
- Cdca5 tm1.1(KOMP)Vlcg
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CDCA5
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CDCA5 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CDCA5 gene
- Search ViGene Biosciences for CDCA5
CRISPR Products
-
OriGene CRISPR knockouts for CDCA5
- genomics-online: gRNA clones - Search results for available CDCA5 gene related products
- Applied Biological Materials CRISPR for CDCA5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDCA5
- GenScript: Design CRISPR guide RNA sequences for CDCA5
miRNA for CDCA5 Gene
- miRTarBase miRNAs that target CDCA5
miRNA Products
- Search ViGene Biosciences for CDCA5
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CDCA5
- Browse OriGene Inhibitory RNA Products For CDCA5
- genomics-online: shRNA clones - Search results for available CDCA5 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CDCA5 gene
Clone Products
- Sino Biological Human cDNA Clone for CDCA5
- VectorBuilder custom plasmid, inducible vectors for CDCA5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDCA5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available CDCA5 gene related products
- orf clones - Search results for available CDCA5 gene related products
- Applied Biological Materials Clones for CDCA5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for CDCA5 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CDCA5 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CDCA5 gene
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CDCA5 Gene
Localization for CDCA5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CDCA5 Gene
- Nucleus. Chromosome. Cytoplasm. Note=Associates with nuclear chromatin from S phase until metaphase and is released in the cytoplasm upon nuclear envelope breakdown.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| plasma membrane | 2 |
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000775 | chromosome, centromeric region | TAS | -- |
| GO:0000785 | chromatin | IEA | -- |
| GO:0000790 | nuclear chromatin | IEA,ISS | -- |
| GO:0005634 | nucleus | IBA,ISS | -- |
| GO:0005654 | nucleoplasm | IDA,TAS | -- |
Pathways & Interactions for CDCA5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cell Cycle, Mitotic |
.83
|
.60
|
| 2 | Mitotic Metaphase and Anaphase |
.94
|
|
| 3 | CDK-mediated phosphorylation and removal of Cdc6 |
.78
|
|
| 4 | Mitotic Prometaphase | ||
| 5 | MicroRNAs in cancer | ||
Pathways by source for CDCA5 Gene
10 Reactome pathways for CDCA5 Gene
1 KEGG pathway for CDCA5 Gene
Interacting Proteins for CDCA5 Gene
Selected Interacting proteins:
Q96FF9-CDCA5_HUMAN
ENSP00000275517
for CDCA5 Gene via
MINT
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000278 | mitotic cell cycle | IDA | 15837422 |
| GO:0006302 | double-strand break repair | IMP | 17349791 |
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007062 | sister chromatid cohesion | TAS | -- |
| GO:0007064 | mitotic sister chromatid cohesion | IPI,IEA | 21111234 |
No data available for SIGNOR curated interactions for CDCA5 Gene
Transcripts for CDCA5 Gene
mRNA/cDNA for CDCA5 Gene
- (8) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (311) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CDCA5 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CDCA5
- genomics-online: gRNA clones - Search results for available CDCA5 gene related products
- Applied Biological Materials CRISPR for CDCA5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDCA5
- GenScript: Design CRISPR guide RNA sequences for CDCA5
miRNA Products
- Search ViGene Biosciences for CDCA5
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CDCA5
- Browse OriGene Inhibitory RNA Products For CDCA5
- genomics-online: shRNA clones - Search results for available CDCA5 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CDCA5 gene
Clone Products
- Sino Biological Human cDNA Clone for CDCA5
- VectorBuilder custom plasmid, inducible vectors for CDCA5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDCA5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available CDCA5 gene related products
- orf clones - Search results for available CDCA5 gene related products
- Applied Biological Materials Clones for CDCA5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||
| SP3: | |||||||||||||||||||||
| SP4: |
Expression for CDCA5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Testis (Reproductive System)
- XY Germ Cells Testis Cord
-
Gonad
- XY Germ Cells Testis Cord
- Gut Tube (Gastrointestinal Tract)
- Kidney (Urinary System)
- Thymus (Hematopoietic System)
-
Lymph (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for CDCA5 Gene
This gene is overexpressed in Testis (x9.5).
This gene is overexpressed in Fetal ovary (55.8) and Fetal Liver (12.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CDCA5 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CDCA5 Gene:
CDCA5SOURCE GeneReport for Unigene cluster for CDCA5 Gene:
Hs.434886Evidence on tissue expression from TISSUES for CDCA5 Gene
- Lung(4.1)
- Nervous system(2.6)
Primer Products
-
OriGene qPCR primer pairs and template standards for CDCA5
-
OriGene qPCR primer pairs for CDCA5
- genomics-online: primer clones - Search results for available CDCA5 gene related products
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CDCA5 Gene
Orthologs for CDCA5 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CDCA5 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | LOC612071 33 |
|
||
| CDCA5 34 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | CDCA5 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC100910252 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Cdca5 33 16 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CDCA5 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cdca5 33 |
|
||
| Str.11789 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.12922 33 |
|
- Species where no ortholog for CDCA5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for CDCA5 Gene
No data available for Paralogs for CDCA5 Gene
Variants for CDCA5 Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000120658 | -- | 65,060,876(-) | A/G | downstream_transcript_variant | |
| rs1000325779 | -- | 65,072,230(-) | A/C | genic_downstream_transcript_variant, intron_variant | |
| rs1000382963 | -- | 65,071,901(-) | A/G | genic_downstream_transcript_variant, intron_variant | |
| rs1000642684 | -- | 65,078,371(-) | C/A/T | 3_prime_UTR_variant, intron_variant | |
| rs1000727908 | -- | 65,062,345(-) | C/T | downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant |
Residual Variation Intolerance Score:
80.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.47;
43.38% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CDCA5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CDCA5
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDCA5 Gene
Disorders for CDCA5 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| cornelia de lange syndrome |
|
|
Search CDCA5 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CDCA5
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for CDCA5 Gene
Publications for CDCA5 Gene
- Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates. (PMID: 15837422) Rankin S … Kirschner MW (Molecular cell 2005) 2 3 4 22 58
- Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase. (PMID: 17349791) Schmitz J … Peters JM (Current biology : CB 2007) 3 4 22 58
- Drug target discovery by gene expression analysis: cell cycle genes. (PMID: 12188893) Walker MG (Current cancer drug targets 2001) 2 3 4 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- Sororin mediates sister chromatid cohesion by antagonizing Wapl. (PMID: 21111234) Nishiyama T … Peters JM (Cell 2010) 3 4 58
Products for CDCA5 Gene
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- Novus Biologicals Antibodies for CDCA5
- Novus Biologicals lysates and proteins for CDCA5
- Novus Biologicals
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for CDCA5
- VectorBuilder custom plasmid, inducible vectors for CDCA5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDCA5
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 32 available CDCA5 Antibodies ranked by validation data
- Compare Top CDCA5 Antibodies
- antibodies-online: Search results for available CDCA5 related products ranked by validation data
- antibodies-online: Search results for 4 available CDCA5 Proteins ranked by validation data
- Compare Top CDCA5 Proteins
- GeneTex CDCA5 antibody for CDCA5
- Search GeneTex for Proteins for CDCA5
- ViGene Biosciences adenoviral particle packaged cDNA for CDCA5 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CDCA5 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CDCA5 gene
- Search ViGene Biosciences for CDCA5
- Santa Cruz Biotechnology (SCBT) Antibodies for CDCA5
- Search Santa Cruz Biotechnology (SCBT) for CDCA5 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CDCA5
- genomics-online: cdna clones - Search results for available CDCA5 gene related products
- orf clones - Search results for available CDCA5 gene related products
- genomics-online: gRNA clones - Search results for available CDCA5 gene related products
- genomics-online: primer clones - Search results for available CDCA5 gene related products
- genomics-online: shRNA clones - Search results for available CDCA5 gene related products
Sources for CDCA5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
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