Aliases for CDC42SE1 Gene
External Ids for CDC42SE1 Gene
Previous GeneCards Identifiers for CDC42SE1 Gene
GeneCards Summary for CDC42SE1 Gene
CDC42SE1 (CDC42 Small Effector 1) is a Protein Coding gene. Diseases associated with CDC42SE1 include Renal Cell Carcinoma, Papillary, 1. Among its related pathways are Actin Nucleation by ARP-WASP Complex and G-protein signaling RAC1 in cellular process. Gene Ontology (GO) annotations related to this gene include structural molecule activity and GTPase inhibitor activity. An important paralog of this gene is CDC42SE2.
UniProtKB/Swiss-Prot Summary for CDC42SE1 Gene
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.