Aliases for CDC42SE1 Gene
External Ids for CDC42SE1 Gene
Previous GeneCards Identifiers for CDC42SE1 Gene
GeneCards Summary for CDC42SE1 Gene
CDC42SE1 (CDC42 Small Effector 1) is a Protein Coding gene. Diseases associated with CDC42SE1 include Cardiomyopathy, Dilated, 1M and Cardiomyopathy, Familial Hypertrophic, 7. Among its related pathways are G-protein signaling RAC1 in cellular process and Actin Nucleation by ARP-WASP Complex. Gene Ontology (GO) annotations related to this gene include structural molecule activity and GTPase inhibitor activity. An important paralog of this gene is CDC42SE2.
UniProtKB/Swiss-Prot Summary for CDC42SE1 Gene
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.