Aliases for CDC23 Gene
Aliases for CDC23 Gene
External Ids for CDC23 Gene
- HGNC: 1724
- Entrez Gene: 8697
- Ensembl: ENSG00000094880
- OMIM: 603462
- UniProtKB: Q9UJX2
Previous GeneCards Identifiers for CDC23 Gene
- GC05M137398
- GC05M137554
- GC05M137599
- GC05M137552
- GC05M132714
Summaries for CDC23 Gene
-
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008]
GeneCards Summary for CDC23 Gene
CDC23 (Cell Division Cycle 23) is a Protein Coding gene. Among its related pathways are PAK Pathway and Actin Nucleation by ARP-WASP Complex. Gene Ontology (GO) annotations related to this gene include ubiquitin-protein transferase activity.
UniProtKB/Swiss-Prot for CDC23 Gene
-
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of Lys-11-linked polyubiquitin chains and, to a lower extent, the formation of Lys-48- and Lys-63-linked polyubiquitin chains.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDC23 Gene
Genomics for CDC23 Gene
GeneHancer (GH) Regulatory Elements for CDC23 Gene
Promoters and enhancers for CDC23 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CDC23 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for CDC23 Gene
Genomic Locations for CDC23 Gene
- chr5:138,187,648-138,213,343
- (GRCh38/hg38)
- Size:
- 25,696 bases
- Orientation:
- Minus strand
- chr5:137,523,337-137,549,032
- (GRCh37/hg19)
Genomic View for CDC23 Gene
Genes around CDC23 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q31.2 by Ensembl
- 5q31.2 by Entrez Gene
- 5q31.2 by HGNC
CDC23 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CDC23 Gene
Proteins for CDC23 Gene
-
Protein details for CDC23 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UJX2-CDC23_HUMAN
- Recommended name:
- Cell division cycle protein 23 homolog
- Protein Accession:
- Q9UJX2
- A8K6E5
- B4E3A2
- B7WP05
- D3DQB7
- O75433
- Q53FN2
- Q9BS73
Protein attributes for CDC23 Gene
- Size:
- 597 amino acids
- Molecular mass:
- 68834 Da
- Quaternary structure:
-
- The mammalian APC/C is composed of 14 distinct subunits that assemble into a complex of at least 19 chains with a combined molecular mass of around 1.2 MDa.
- SequenceCaution:
-
- Sequence=AAC70920.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH05258.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH10944.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH17713.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAS99353.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA75628.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAD96970.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAF84299.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for CDC23 Gene
Protein Expression for CDC23 Gene
Post-translational modifications for CDC23 Gene
- Phosphorylated. Phosphorylation on Thr-562 occurs specifically during mitosis.
- Ubiquitination at posLast=445445, Lys453, and Lys547
- Modification sites at PhosphoSitePlus
Other Protein References for CDC23 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for CDC23
-
Abcam antibodies for CDC23
-
Cloud-Clone Corp. Antibodies for CDC23
- Invitrogen Antibodies for CDC23
- GeneTex CDC23 antibody for CDC23
-
Custom Antibody ServicesProSci Antibodies for CDC23
-
Santa Cruz Biotechnology (SCBT) Antibodies for CDC23
Protein Products
-
OriGene Purified Proteins for CDC23
- Search Origene for MassSpec and Protein Over-expression Lysates for CDC23
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-
Cloud-Clone Corp. Proteins for CDC23
- Search GeneTex for Proteins for CDC23
-
Abcam proteins for CDC23
Assay Products
No data available for DME Specific Peptides for CDC23 Gene
Domains & Families for CDC23 Gene
Gene Families for CDC23 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
Protein Domains for CDC23 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CDC23 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UJX2- Family:
-
- Belongs to the APC8/CDC23 family.
Function for CDC23 Gene
Molecular function for CDC23 Gene
- GENATLAS Biochemistry:
- cell division cycle (CDC)23,S cerevisiae homolog,component of the anaphase promoting complex,involved in ubiquitin mediated proteolysis,commonly deleted in myeloid leukemias,but unlikely to be involved in the pathogenesis of this disease
- UniProtKB/Swiss-Prot Function:
- Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of Lys-11-linked polyubiquitin chains and, to a lower extent, the formation of Lys-48- and Lys-63-linked polyubiquitin chains.
Phenotypes From GWAS Catalog for CDC23 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | TAS | 12629511 |
| GO:0005515 | protein binding | IPI | 16189514 |
Phenotypes for CDC23 Gene
- GenomeRNAi human phenotypes for CDC23:
-
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased ionizing radiation sensitivity
- Decreased viability ratio
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection
- Dynamic nuclei (hole, folded or small irregular)
- Effect on mitosis
- Increased cell number in S
- Increased cell death HMECs cells
- Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435)
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CDC23
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CDC23 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CDC23 gene
- Search ViGene Biosciences for CDC23
CRISPR Products
-
OriGene CRISPR knockouts for CDC23
- genomics-online: gRNA clones - Search results for available CDC23 gene related products
- Applied Biological Materials CRISPR for CDC23
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDC23
- GenScript: Design CRISPR guide RNA sequences for CDC23
miRNA for CDC23 Gene
- miRTarBase miRNAs that target CDC23
-
- hsa-mir-340-5p (MIRT019590)
- hsa-mir-29c-3p (MIRT020394)
- hsa-mir-34a-5p (MIRT025367)
- hsa-mir-98-5p (MIRT027586)
- hsa-mir-16-5p (MIRT031557)
- hsa-mir-4777-5p (MIRT095308)
- hsa-mir-204-5p (MIRT095328)
- hsa-mir-211-5p (MIRT095329)
- hsa-mir-623 (MIRT095331)
- hsa-mir-6832-3p (MIRT095335)
- hsa-mir-5006-3p (MIRT558843)
- hsa-mir-4755-5p (MIRT558844)
- hsa-mir-519e-5p (MIRT558845)
- hsa-mir-515-5p (MIRT558846)
- hsa-mir-4777-3p (MIRT558847)
- hsa-mir-767-5p (MIRT558848)
- hsa-mir-145-3p (MIRT558849)
- hsa-mir-3663-3p (MIRT558850)
- hsa-mir-5695 (MIRT558851)
- hsa-mir-519d-5p (MIRT558852)
- hsa-mir-6891-3p (MIRT558853)
- hsa-mir-6072 (MIRT558854)
- hsa-mir-335-5p (MIRT558855)
- hsa-mir-3938 (MIRT558856)
- hsa-mir-29b-3p (MIRT558857)
- hsa-mir-29a-3p (MIRT558858)
- hsa-mir-580-5p (MIRT558859)
miRNA Products
- Search ViGene Biosciences for CDC23
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CDC23
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- genomics-online: shRNA clones - Search results for available CDC23 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CDC23 gene
Clone Products
- Sino Biological Human cDNA Clone for CDC23
- VectorBuilder custom plasmid, inducible vectors for CDC23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDC23
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available CDC23 gene related products
- orf clones - Search results for available CDC23 gene related products
- Applied Biological Materials Clones for CDC23
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for CDC23 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CDC23 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CDC23 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CDC23 Gene
Localization for CDC23 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| extracellular | 2 |
| endoplasmic reticulum | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IDA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005680 | anaphase-promoting complex | IDA,TAS | 14657031 |
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for CDC23 Gene
Pathways & Interactions for CDC23 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | CDK-mediated phosphorylation and removal of Cdc6 | ||
| 2 | APC-Cdc20 mediated degradation of Nek2A | ||
| 3 | Class I MHC mediated antigen processing and presentation | ||
| 4 | Cell Cycle, Mitotic |
.83
|
.60
|
| 5 | Cellular Senescence (REACTOME) | ||
Pathways by source for CDC23 Gene
31 Reactome pathways for CDC23 Gene
5 KEGG pathways for CDC23 Gene
6 Qiagen pathways for CDC23 Gene
1 Cell Signaling Technology pathway for CDC23 Gene
UniProtKB/Swiss-Prot Q9UJX2-CDC23_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for CDC23 Gene
Selected Interacting proteins:
Q9UJX2-CDC23_HUMAN
ENSP00000378350
for CDC23 Gene via
MINT
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000278 | mitotic cell cycle | IDA | 14657031 |
| GO:0006511 | ubiquitin-dependent protein catabolic process | TAS | 9790767 |
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007080 | mitotic metaphase plate congression | IDA | 14657031 |
| GO:0007091 | metaphase/anaphase transition of mitotic cell cycle | TAS | 9790767 |
Transcripts for CDC23 Gene
mRNA/cDNA for CDC23 Gene
- (1) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (227) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CDC23 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CDC23
- genomics-online: gRNA clones - Search results for available CDC23 gene related products
- Applied Biological Materials CRISPR for CDC23
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDC23
- GenScript: Design CRISPR guide RNA sequences for CDC23
miRNA Products
- Search ViGene Biosciences for CDC23
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CDC23
- Browse OriGene Inhibitory RNA Products For CDC23
- genomics-online: shRNA clones - Search results for available CDC23 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CDC23 gene
Clone Products
- Sino Biological Human cDNA Clone for CDC23
- VectorBuilder custom plasmid, inducible vectors for CDC23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDC23
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available CDC23 gene related products
- orf clones - Search results for available CDC23 gene related products
- Applied Biological Materials Clones for CDC23
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| SP2: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
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| SP6: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: |
| ExUns: | 17a | · | 17b |
|---|---|---|---|
| SP1: | |||
| SP2: | |||
| SP3: | |||
| SP4: | |||
| SP5: | |||
| SP6: | |||
| SP7: | |||
| SP8: | |||
| SP9: | |||
| SP10: |
Expression for CDC23 Gene
This gene is overexpressed in Bone marrow mesenchymal stem cell (53.2) and Breast (8.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CDC23 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CDC23 Gene:
CDC23SOURCE GeneReport for Unigene cluster for CDC23 Gene:
Hs.73625Evidence on tissue expression from TISSUES for CDC23 Gene
- Nervous system(4.8)
- Bone marrow(4.2)
- Intestine(4.2)
- Liver(4.2)
- Stomach(4.2)
- Pancreas(4.1)
Primer Products
-
OriGene qPCR primer pairs for CDC23
-
OriGene qPCR primer pairs and template standards for CDC23
- genomics-online: primer clones - Search results for available CDC23 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CDC23 Gene
Orthologs for CDC23 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CDC23 33 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CDC23 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | CDC23 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | CDC23 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cdc23 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Cdc23 33 16 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CDC23 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CDC23 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CDC23 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cdc23 33 |
|
||
| Str.8410 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | cdc23 33 34 |
|
||
| zgc56013 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | cdc23 33 34 |
|
||
| CG2508 35 |
|
|
|||
| CG31687 34 |
|
OneToMany | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP009880 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | mat-3 35 34 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0A05258g 33 |
|
||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_ABR206W 33 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | CDC23 33 34 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | APC8 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os02g0656300 33 |
|
||
| Os.22624 33 |
|
||||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU01174 33 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | cut23 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.8976 34 |
|
OneToOne | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.5916 33 |
|
- Species where no ortholog for CDC23 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for CDC23 Gene
No data available for Paralogs for CDC23 Gene
Variants for CDC23 Gene
| SNP ID | Clin | Chr 05 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000001862 | -- | 138,208,691(-) | T/C | intron_variant | |
| rs1000035697 | -- | 138,211,387(-) | G/C | intron_variant | |
| rs1000101623 | -- | 138,201,280(-) | T/A | intron_variant | |
| rs1000256745 | -- | 138,192,726(-) | G/T | intron_variant | |
| rs1000370993 | -- | 138,202,067(-) | G/A | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2670577 | CNV | deletion | 23128226 |
| esv3606919 | CNV | loss | 21293372 |
Residual Variation Intolerance Score:
16% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.54;
44.32% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CDC23 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDC23 Gene
Disorders for CDC23 Gene
Additional Disease Information for CDC23
No disorders were found for CDC23 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CDC23 Gene
Publications for CDC23 Gene
- Human CDC23: cDNA cloning, mapping to 5q31, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias. (PMID: 9790767) Zhao N … Le Beau MM (Genomics 1998) 2 3 4 22 58
- Molecular architecture and mechanism of the anaphase-promoting complex. (PMID: 25043029) Chang LF … Barford D (Nature 2014) 3 4 58
- Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. (PMID: 18485873) Jin L … Rape M (Cell 2008) 3 4 58
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil SA … Gygi SP (Nature biotechnology 2006) 3 4 58
- Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. (PMID: 16364912) Dube P … Stark H (Molecular cell 2005) 3 4 58
Products for CDC23 Gene
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- Browse ELISA Kits
- Abcam antibodies for CDC23
- Abcam proteins for CDC23
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Cloud-Clone Corp. Antibodies for CDC23
- Cloud-Clone Corp. Proteins for CDC23
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for CDC23
- VectorBuilder custom plasmid, inducible vectors for CDC23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDC23
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 65 available CDC23 Antibodies ranked by validation data
- Compare Top CDC23 Antibodies
- antibodies-online: Search results for 20 available CDC23 Elisa Kits ranked by validation data
- Compare Top CDC23 Elisa Kits
- antibodies-online: Search results for 9 available CDC23 Proteins ranked by validation data
- Compare Top CDC23 Proteins
- GeneTex CDC23 antibody for CDC23
- Search GeneTex for Proteins for CDC23
- ViGene Biosciences adenoviral particle packaged cDNA for CDC23 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CDC23 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CDC23 gene
- Search ViGene Biosciences for CDC23
- Santa Cruz Biotechnology (SCBT) Antibodies for CDC23
- Search Santa Cruz Biotechnology (SCBT) for CDC23 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CDC23
- Custom Antibody ServicesProSci Antibodies for CDC23
- Search for CDC23 Proteins at ProSci
- genomics-online: cdna clones - Search results for available CDC23 gene related products
- orf clones - Search results for available CDC23 gene related products
- genomics-online: gRNA clones - Search results for available CDC23 gene related products
- genomics-online: primer clones - Search results for available CDC23 gene related products
- genomics-online: shRNA clones - Search results for available CDC23 gene related products
Sources for CDC23 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
