Aliases for CDC23 Gene
Aliases for CDC23 Gene
External Ids for CDC23 Gene
- HGNC: 1724
- Entrez Gene: 8697
- Ensembl: ENSG00000094880
- OMIM: 603462
- UniProtKB: Q9UJX2
Previous GeneCards Identifiers for CDC23 Gene
- GC05M137398
- GC05M137554
- GC05M137599
- GC05M137552
- GC05M132714
Summaries for CDC23 Gene
-
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008]
GeneCards Summary for CDC23 Gene
CDC23 (Cell Division Cycle 23) is a Protein Coding gene. Among its related pathways are Cell Cycle, Mitotic and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include ubiquitin-protein transferase activity.
UniProtKB/Swiss-Prot for CDC23 Gene
-
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of Lys-11-linked polyubiquitin chains and, to a lower extent, the formation of Lys-48- and Lys-63-linked polyubiquitin chains.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDC23 Gene
Genomics for CDC23 Gene
GeneHancer (GH) Regulatory Elements for CDC23 Gene
Promoters and enhancers for CDC23 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CDC23 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for CDC23 Gene
Genomic Locations for CDC23 Gene
- chr5:138,187,648-138,213,343
- (GRCh38/hg38)
- Size:
- 25,696 bases
- Orientation:
- Minus strand
- chr5:137,523,337-137,549,032
- (GRCh37/hg19)
Genomic View for CDC23 Gene
Genes around CDC23 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q31.2 by Entrez Gene
- 5q31.2 by HGNC
- 5q31.2 by Ensembl
CDC23 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CDC23 Gene
Proteins for CDC23 Gene
-
Protein details for CDC23 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UJX2-CDC23_HUMAN
- Recommended name:
- Cell division cycle protein 23 homolog
- Protein Accession:
- Q9UJX2
- A8K6E5
- B4E3A2
- B7WP05
- D3DQB7
- O75433
- Q53FN2
- Q9BS73
Protein attributes for CDC23 Gene
- Size:
- 597 amino acids
- Molecular mass:
- 68834 Da
- Quaternary structure:
-
- The mammalian APC/C is composed of 14 distinct subunits that assemble into a complex of at least 19 chains with a combined molecular mass of around 1.2 MDa.
- SequenceCaution:
-
- Sequence=AAC70920.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH05258.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH10944.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH17713.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAS99353.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA75628.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAD96970.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAF84299.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for CDC23 Gene
Protein Expression for CDC23 Gene
Post-translational modifications for CDC23 Gene
- Phosphorylated. Phosphorylation on Thr-562 occurs specifically during mitosis.
- Ubiquitination at Lys547, posLast=453453, and posLast=445445
- Modification sites at PhosphoSitePlus
Other Protein References for CDC23 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for CDC23
- Invitrogen Antibodies for CDC23
- GeneTex CDC23 Antibody for CDC23
-
Custom Antibody ServicesProSci Antibodies for CDC23
-
Santa Cruz Biotechnology (SCBT) Antibodies for CDC23
Protein Products
-
OriGene Purified Proteins for CDC23
- Search Origene for MassSpec and Protein Over-expression Lysates for CDC23
- Origene Custom Protein Services for CDC23
- Search GeneTex for Proteins for CDC23
Assay Products
No data available for DME Specific Peptides for CDC23 Gene
Domains & Families for CDC23 Gene
Gene Families for CDC23 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
Protein Domains for CDC23 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CDC23 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UJX2- Family:
-
- Belongs to the APC8/CDC23 family.
Function for CDC23 Gene
Molecular function for CDC23 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of Lys-11-linked polyubiquitin chains and, to a lower extent, the formation of Lys-48- and Lys-63-linked polyubiquitin chains.
- GENATLAS Biochemistry:
- cell division cycle (CDC)23,S cerevisiae homolog,component of the anaphase promoting complex,involved in ubiquitin mediated proteolysis,commonly deleted in myeloid leukemias,but unlikely to be involved in the pathogenesis of this disease
Phenotypes From GWAS Catalog for CDC23 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | TAS | 12629511 |
| GO:0005515 | protein binding | IPI | 16189514 |
Phenotypes for CDC23 Gene
- GenomeRNAi human phenotypes for CDC23:
-
- Decreased viability ratio
- Effect on mitosis
- Dynamic nuclei (hole, folded or small irregular)
- Increased cell death HMECs cells
- Reduced mammosphere formation
- Decreased ionizing radiation sensitivity
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435)
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection
- Increased cell number in S
- shRNA abundance <= 50%
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CDC23
-
CRISPR Products
-
OriGene CRISPR knockouts for CDC23
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CDC23
- genomics-online: gRNA clones - Search results for available CDC23 gene related products
- Applied Biological Materials CRISPR for CDC23
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDC23
- GenScript: Design CRISPR guide RNA sequences for CDC23
miRNA for CDC23 Gene
- miRTarBase miRNAs that target CDC23
-
- hsa-mir-340-5p (MIRT019590)
- hsa-mir-29c-3p (MIRT020394)
- hsa-mir-34a-5p (MIRT025367)
- hsa-mir-98-5p (MIRT027586)
- hsa-mir-16-5p (MIRT031557)
- hsa-mir-4777-5p (MIRT095308)
- hsa-mir-204-5p (MIRT095328)
- hsa-mir-211-5p (MIRT095329)
- hsa-mir-623 (MIRT095331)
- hsa-mir-6832-3p (MIRT095335)
- hsa-mir-5006-3p (MIRT558843)
- hsa-mir-4755-5p (MIRT558844)
- hsa-mir-519e-5p (MIRT558845)
- hsa-mir-515-5p (MIRT558846)
- hsa-mir-4777-3p (MIRT558847)
- hsa-mir-767-5p (MIRT558848)
- hsa-mir-145-3p (MIRT558849)
- hsa-mir-3663-3p (MIRT558850)
- hsa-mir-5695 (MIRT558851)
- hsa-mir-519d-5p (MIRT558852)
- hsa-mir-6891-3p (MIRT558853)
- hsa-mir-6072 (MIRT558854)
- hsa-mir-335-5p (MIRT558855)
- hsa-mir-3938 (MIRT558856)
- hsa-mir-29b-3p (MIRT558857)
- hsa-mir-29a-3p (MIRT558858)
- hsa-mir-580-5p (MIRT558859)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CDC23
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CDC23
- genomics-online: shRNA clones - Search results for available CDC23 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CDC23
- VectorBuilder custom plasmid, inducible vectors for CDC23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDC23
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CDC23
- genomics-online: cdna clones - Search results for available CDC23 gene related products
- orf clones - Search results for available CDC23 gene related products
- Applied Biological Materials Clones for CDC23
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CDC23 Gene
Localization for CDC23 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| extracellular | 2 |
| endoplasmic reticulum | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IDA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005680 | anaphase-promoting complex | IDA,TAS | 14657031 |
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for CDC23 Gene
Pathways & Interactions for CDC23 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | CDK-mediated phosphorylation and removal of Cdc6 | ||
| 2 | APC-Cdc20 mediated degradation of Nek2A | ||
| 3 | Class I MHC mediated antigen processing and presentation | ||
| 4 | Cell Cycle, Mitotic |
.83
|
.60
|
| 5 | Cellular Senescence (REACTOME) | ||
Pathways by source for CDC23 Gene
31 Reactome pathways for CDC23 Gene
5 KEGG pathways for CDC23 Gene
6 Qiagen pathways for CDC23 Gene
1 Cell Signaling Technology pathway for CDC23 Gene
UniProtKB/Swiss-Prot Q9UJX2-CDC23_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for CDC23 Gene
Selected Interacting proteins:
Q9UJX2-CDC23_HUMAN
ENSP00000378350
for CDC23 Gene via
IID
UniProtKB
MINT
STRING
GPS-Prot Interaction Network for CDC23
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000278 | mitotic cell cycle | IDA | 14657031 |
| GO:0006511 | ubiquitin-dependent protein catabolic process | TAS | 9790767 |
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007080 | mitotic metaphase plate congression | IDA | 14657031 |
| GO:0007091 | metaphase/anaphase transition of mitotic cell cycle | TAS | 9790767 |
Transcripts for CDC23 Gene
mRNA/cDNA for CDC23 Gene
- (227) Selected AceView cDNA sequences:
- (10) Additional mRNA sequences :
- (1) REFSEQ mRNAs :
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000394884 1079 bps (uc003lcm.2)
- ENST00000394886 3155 bps (uc003lcl.3)
- ENST00000464806 562 bps (uc063hkc.1)
- ENST00000471692 1104 bps (uc063hke.1)
- ENST00000475021 473 bps (uc063hkd.1)
Unigene Clusters for CDC23 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CDC23
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CDC23
- genomics-online: gRNA clones - Search results for available CDC23 gene related products
- Applied Biological Materials CRISPR for CDC23
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CDC23
- GenScript: Design CRISPR guide RNA sequences for CDC23
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CDC23
- Browse OriGene Inhibitory RNA Products For CDC23
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CDC23
- genomics-online: shRNA clones - Search results for available CDC23 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CDC23
- VectorBuilder custom plasmid, inducible vectors for CDC23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDC23
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CDC23
- genomics-online: cdna clones - Search results for available CDC23 gene related products
- orf clones - Search results for available CDC23 gene related products
- Applied Biological Materials Clones for CDC23
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| SP6: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
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| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: |
| ExUns: | 17a | · | 17b |
|---|---|---|---|
| SP1: | |||
| SP2: | |||
| SP3: | |||
| SP4: | |||
| SP5: | |||
| SP6: | |||
| SP7: | |||
| SP8: | |||
| SP9: | |||
| SP10: |
Expression for CDC23 Gene
This gene is overexpressed in Bone marrow mesenchymal stem cell (53.2) and Breast (8.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CDC23 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CDC23 Gene:
CDC23SOURCE GeneReport for Unigene cluster for CDC23 Gene:
Hs.73625Evidence on tissue expression from TISSUES for CDC23 Gene
- Nervous system(4.8)
- Bone marrow(4.2)
- Intestine(4.2)
- Liver(4.2)
- Stomach(4.2)
- Pancreas(4.1)
Primer Products
-
OriGene qPCR primer pairs and template standards for CDC23
-
OriGene qPCR primer pairs for CDC23
- genomics-online: primer clones - Search results for available CDC23 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CDC23 Gene
Orthologs for CDC23 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CDC23 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | CDC23 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | CDC23 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | CDC23 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Cdc23 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Cdc23 16 34 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CDC23 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CDC23 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | CDC23 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cdc23 33 |
|
||
| Str.8410 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | cdc23 34 33 |
|
OneToOne | |
| zgc56013 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | cdc23 34 33 |
|
OneToMany | |
| CG2508 35 |
|
|
|||
| CG31687 34 |
|
OneToMany | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP009880 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | mat-3 34 35 |
|
OneToOne | |
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0A05258g 33 |
|
||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_ABR206W 33 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | CDC23 34 33 |
|
OneToOne | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | APC8 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os02g0656300 33 |
|
||
| Os.22624 33 |
|
||||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU01174 33 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | cut23 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.8976 34 |
|
OneToOne | |
| Cin.5916 33 |
|
||||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.5916 33 |
|
- Species where no ortholog for CDC23 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for CDC23 Gene
- ENSEMBL:
- Gene Tree for CDC23 (if available)
- TreeFam:
- Gene Tree for CDC23 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CDC23: view image
Paralogs for CDC23 Gene
No data available for Paralogs for CDC23 Gene
Variants for CDC23 Gene
| SNP ID | Clin | Chr 05 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000001862 | -- | 138,208,691(-) | T/C | intron_variant | |
| rs1000035697 | -- | 138,211,387(-) | G/C | intron_variant | |
| rs1000101623 | -- | 138,201,280(-) | T/A | intron_variant | |
| rs1000256745 | -- | 138,192,726(-) | G/T | intron_variant | |
| rs1000370993 | -- | 138,202,067(-) | G/A | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2670577 | CNV | deletion | 23128226 |
| esv3606919 | CNV | loss | 21293372 |
Residual Variation Intolerance Score:
16% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.54;
44.32% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CDC23 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDC23 Gene
Disorders for CDC23 Gene
Additional Disease Information for CDC23
No disorders were found for CDC23 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CDC23 Gene
Publications for CDC23 Gene
- Human CDC23: cDNA cloning, mapping to 5q31, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias. (PMID: 9790767) Zhao N … Le Beau MM (Genomics 1998) 2 3 4 22 58
- Molecular architecture and mechanism of the anaphase-promoting complex. (PMID: 25043029) Chang LF … Barford D (Nature 2014) 3 4 58
- Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. (PMID: 18485873) Jin L … Rape M (Cell 2008) 3 4 58
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil SA … Gygi SP (Nature biotechnology 2006) 3 4 58
- Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. (PMID: 16364912) Dube P … Stark H (Molecular cell 2005) 3 4 58
Products for CDC23 Gene
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- OriGene Purified Proteins for CDC23
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- Sino Biological Human cDNA Clone for CDC23
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for CDC23
- Novus Biologicals proteins and lysates for CDC23
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder custom plasmid, inducible vectors for CDC23
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CDC23
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 65 available CDC23 Antibodies ranked by validation data
- Compare Top CDC23 Antibodies
- antibodies-online: Search results for 20 available CDC23 Elisa Kits ranked by validation data
- Compare Top CDC23 Elisa Kits
- antibodies-online: Search results for 9 available CDC23 Proteins ranked by validation data
- Compare Top CDC23 Proteins
- GeneTex CDC23 Antibody for CDC23
- Search GeneTex for Proteins for CDC23
- Santa Cruz Biotechnology (SCBT) Antibodies for CDC23
- Search Santa Cruz Biotechnology (SCBT) for CDC23 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CDC23
- Custom Antibody ServicesProSci Antibodies for CDC23
- Search for CDC23 Proteins at ProSci
- genomics-online: cdna clones - Search results for available CDC23 gene related products
- orf clones - Search results for available CDC23 gene related products
- genomics-online: gRNA clones - Search results for available CDC23 gene related products
- genomics-online: primer clones - Search results for available CDC23 gene related products
- genomics-online: shRNA clones - Search results for available CDC23 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CDC23
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CDC23
- GeneCopoeia miRNA 3'UTR Target clone products for CDC23
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CDC23
Sources for CDC23 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio