Aliases for CD99L2 Gene
External Ids for CD99L2 Gene
Previous HGNC Symbols for CD99L2 Gene
Previous GeneCards Identifiers for CD99L2 Gene
This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
GeneCards Summary for CD99L2 Gene
CD99L2 (CD99 Molecule Like 2) is a Protein Coding gene. Diseases associated with CD99L2 include Chorioangioma. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling and Cell surface interactions at the vascular wall. An important paralog of this gene is CD99.
UniProtKB/Swiss-Prot Summary for CD99L2 Gene
Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1 (By similarity). Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity).