Aliases for CD96 Gene
External Ids for CD96 Gene
Previous GeneCards Identifiers for CD96 Gene
The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]
GeneCards Summary for CD96 Gene
CD96 (CD96 Molecule) is a Protein Coding gene. Diseases associated with CD96 include C Syndrome and Leukemia, Acute Myeloid. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Class I MHC mediated antigen processing and presentation.
UniProtKB/Swiss-Prot Summary for CD96 Gene
May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation.