The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the ... See more...

Aliases for CD38 Gene

Aliases for CD38 Gene

  • CD38 Molecule 2 3 5
  • ADP-Ribosyl Cyclase 1 2 3 4
  • ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1 3 4
  • 2'-Phospho-Cyclic-ADP-Ribose Transferase 3 4
  • 2'-Phospho-ADP-Ribosyl Cyclase 3 4
  • Cyclic ADP-Ribose Hydrolase 1 3 4
  • NAD(+) Nucleosidase 2 3
  • CD38 Antigen (P45) 2 3
  • ADPRC 1 3 4
  • 2'-Phospho-ADP-Ribosyl Cyclase/2'-Phospho-Cyclic-ADP-Ribose Transferase 4
  • Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase 3
  • Cluster Of Differentiation 38 3
  • CADPr Hydrolase 1 4
  • CD38 Antigen 4
  • EC 2.4.99.20 4
  • EC 3.2.2.6 4
  • ADPRC1 3
  • CD38 5
  • T10 4

External Ids for CD38 Gene

Previous GeneCards Identifiers for CD38 Gene

  • GC04P015595
  • GC04P015722
  • GC04P015468
  • GC04P015530
  • GC04P015457
  • GC04P015130

Summaries for CD38 Gene

Entrez Gene Summary for CD38 Gene

  • The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

GeneCards Summary for CD38 Gene

CD38 (CD38 Molecule) is a Protein Coding gene. Diseases associated with CD38 include Richter's Syndrome and Prolymphocytic Leukemia. Among its related pathways are Calcium signaling pathway and Cell-type Dependent Selectivity of CCK2R Signaling. Gene Ontology (GO) annotations related to this gene include transferase activity and hydrolase activity, acting on glycosyl bonds. An important paralog of this gene is BST1.

UniProtKB/Swiss-Prot Summary for CD38 Gene

  • Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

Gene Wiki entry for CD38 Gene

Additional gene information for CD38 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CD38 Gene

Genomics for CD38 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CD38 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J015778 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 622 +0.8 818 2.6 CTCF REST POLR2A BACH1 RELA TCF12 IKZF2 SP1 TRIM22 EZH2 CD38 lnc-FBXL5-9 FBXL5 BST1 piR-50129-170 FGFBP1
GH04J015776 Promoter/Enhancer 0.6 Ensembl dbSUPER 600.7 -0.8 -774 0.2 EBF1 CD38 HSALNG0033065 lnc-FBXL5-9 piR-37895-111 BST1
GH04J015753 Enhancer 1.1 FANTOM5 ENCODE dbSUPER 34.2 -22.9 -22862 4.4 CTCF SP1 ARID3A DPF2 CEBPB RUNX3 ARNT NR2F2 NR2F1 RAD21 LOC107986186 CD38 RPL10AP7 TAPT1 FBXL5 LOC100288771 BST1
GH04J015771 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 25.9 -5.5 -5521 3.9 RELA IKZF2 TRIM22 PKNOX1 EED CEBPB SP1 RFX1 DPF2 RELB CD38 FGFBP2 PROM1 ENSG00000273133 FBXL5 HSALNG0033065 piR-32214-519 BST1
GH04J015811 Enhancer 0.7 Ensembl ENCODE 32 +33.9 33907 1.2 TEAD4 REST NFE2 ATF4 ATF3 ATF2 SP1 CD38 FGFBP2 PROM1 piR-38351-326 piR-56759-419 FGFBP1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CD38 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CD38

Top Transcription factor binding sites by QIAGEN in the CD38 gene promoter:
  • AML1a
  • FOXI1
  • HFH-3
  • IRF-1
  • Nkx2-5
  • p53
  • Pax-3
  • PPAR-alpha
  • PPAR-gamma1
  • PPAR-gamma2

Genomic Locations for CD38 Gene

Genomic Locations for CD38 Gene
chr4:15,778,275-15,853,232
(GRCh38/hg38)
Size:
74,958 bases
Orientation:
Plus strand
chr4:15,779,898-15,854,853
(GRCh37/hg19)
Size:
74,956 bases
Orientation:
Plus strand

Genomic View for CD38 Gene

Genes around CD38 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CD38 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CD38 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CD38 Gene

Proteins for CD38 Gene

  • Protein details for CD38 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P28907-CD38_HUMAN
    Recommended name:
    ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
    Protein Accession:
    P28907
    Secondary Accessions:
    • O00121
    • O00122
    • Q96HY4

    Protein attributes for CD38 Gene

    Size:
    300 amino acids
    Molecular mass:
    34328 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

    Three dimensional structures from OCA and Proteopedia for CD38 Gene

    Alternative splice isoforms for CD38 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CD38 Gene

Post-translational modifications for CD38 Gene

  • Glycosylation at Asn100, Asn164, Asn209, and Asn219
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect
    • CD38_HUMAN (997)

Other Protein References for CD38 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Abcam antibodies for CD38

No data available for DME Specific Peptides for CD38 Gene

Domains & Families for CD38 Gene

Gene Families for CD38 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • CD markers
  • Enzymes
  • Predicted intracellular proteins

Protein Domains for CD38 Gene

InterPro:
Blocks:
  • ADP-ribosyl cyclase (CD38/157)
ProtoNet:

Suggested Antigen Peptide Sequences for CD38 Gene

GenScript: Design optimal peptide antigens:
  • T10 (CD38_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P28907

UniProtKB/Swiss-Prot:

CD38_HUMAN :
  • Belongs to the ADP-ribosyl cyclase family.
Family:
  • Belongs to the ADP-ribosyl cyclase family.
genes like me logo Genes that share domains with CD38: view

Function for CD38 Gene

Molecular function for CD38 Gene

UniProtKB/Swiss-Prot Function:
Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide; Xref=Rhea:RHEA:16301, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17154, ChEBI:CHEBI:57540, ChEBI:CHEBI:57967; EC=3.2.2.6; Evidence={ECO:0000269|PubMed:16690024};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=NADP(+) + nicotinate = nicotinamide + nicotinate-adenine dinucleotide phosphate; Xref=Rhea:RHEA:38599, ChEBI:CHEBI:17154, ChEBI:CHEBI:32544, ChEBI:CHEBI:58349, ChEBI:CHEBI:75967; EC=2.4.99.20; Evidence={ECO:0000269|PubMed:16690024};.
UniProtKB/Swiss-Prot EnzymeRegulation:
ATP inhibits the hydrolyzing activity.
GENATLAS Biochemistry:
cell differentiation antigen CD38 (T10),45kDa,membrane glycoprotein,integral,identified by monoclonal antibody OKT10,HB-7,homolog to Aplysia ADRC gene,involved in insulin secretion through mobi-calcium of mobilisation

Enzyme Numbers (IUBMB) for CD38 Gene

Phenotypes From GWAS Catalog for CD38 Gene

Gene Ontology (GO) - Molecular Function for CD38 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003953 NAD+ nucleosidase activity IEA,TAS --
GO:0016740 transferase activity IEA --
GO:0016787 hydrolase activity IEA --
GO:0016798 hydrolase activity, acting on glycosyl bonds IEA --
GO:0016849 phosphorus-oxygen lyase activity IBA 21873635
genes like me logo Genes that share ontologies with CD38: view
genes like me logo Genes that share phenotypes with CD38: view

Animal Models for CD38 Gene

MGI Knock Outs for CD38:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CD38

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CD38 Gene

Localization for CD38 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CD38 Gene

Membrane. Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CD38 gene
Compartment Confidence
plasma membrane 5
extracellular 5
nucleus 4
cytosol 3
cytoskeleton 2
mitochondrion 2
endoplasmic reticulum 2
endosome 2
lysosome 2
golgi apparatus 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Plasma membrane (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CD38 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005623 cell IEA --
GO:0005634 nucleus IEA --
GO:0005886 plasma membrane IEA,TAS --
GO:0009986 cell surface IEA --
GO:0016020 membrane TAS 8253715
genes like me logo Genes that share ontologies with CD38: view

Pathways & Interactions for CD38 Gene

genes like me logo Genes that share pathways with CD38: view

Gene Ontology (GO) - Biological Process for CD38 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001666 response to hypoxia IEA --
GO:0007165 signal transduction NAS 8253715
GO:0007204 positive regulation of cytosolic calcium ion concentration IEA --
GO:0007565 female pregnancy IEA --
GO:0008284 positive regulation of cell proliferation IEA --
genes like me logo Genes that share ontologies with CD38: view

No data available for SIGNOR curated interactions for CD38 Gene

Drugs & Compounds for CD38 Gene

(43) Drugs for CD38 Gene - From: DrugBank, ClinicalTrials, DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Daratumumab Approved Pharma Target, antibody 188
Dexamethasone Approved, Investigational, Vet_approved Pharma Agonist Anti-inflammatory glucocorticoid 2886
Nicotinamide Approved, Investigational Pharma 427,427
NADH Approved Nutra 0
Isatuximab Approved, Investigational Pharma Target, inhibitor 0

(20) Additional Compounds for CD38 Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • 5'-Adenylphosphoric acid
  • Adenosine 5'-diphosphate
  • ADENOSINE-5'-diphosphATE
  • H3ADP
  • 5'-Adenylphosphate
Agonist, Full agonist, Partial agonist, Gating inhibitor, Antagonist 58-64-0
(E)-3-(2,3-Dihydroxyphenyl)-2-propenoic acid
  • 3-(2,3-Dihydroxyphenyl)-2-propenoic acid
  • 3-(2,3-Dihydroxyphenyl)acrylic acid
  • 3-(2,3-Dihydroxyphenyl)-2-propenoate
  • (e)-3-(2,3-Dihydroxyphenyl)-2-propenoate
  • 3-(2,3-Dihydroxyphenyl)acrylate
38481-04-8
Adenosine diphosphate ribose
  • (Rib5)ppa
  • 5-(Adenosine 5'-pyrophosphoryl)-D-ribose
  • a5'pp5RIb
  • Adenosine 5'-diphosphoribose
  • AdoPPRib
20762-30-5
cis-4-decenoic acid
  • 2'-Phosphoadenosine 5'-[3-(D-ribofuranosyl) dihydrogen diphosphate]
  • ADP-D-Ribose 2'-phosphate
  • ADPribose 2'-phosphate
57602-94-5, 26303-90-2
genes like me logo Genes that share compounds with CD38: view

Transcripts for CD38 Gene

mRNA/cDNA for CD38 Gene

1 REFSEQ mRNAs :
9 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CD38

Alternative Splicing Database (ASD) splice patterns (SP) for CD38 Gene

No ASD Table

Relevant External Links for CD38 Gene

GeneLoc Exon Structure for
CD38

Expression for CD38 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CD38 Gene

mRNA differential expression in normal tissues according to GTEx for CD38 Gene

This gene is overexpressed in Spleen (x5.8).

Protein differential expression in normal tissues from HIPED for CD38 Gene

This gene is overexpressed in Seminal vesicle (11.0), Stomach (9.4), Oral epithelium (9.1), and NK cells (8.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CD38 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CD38

SOURCE GeneReport for Unigene cluster for CD38 Gene:

Hs.479214

mRNA Expression by UniProt/SwissProt for CD38 Gene:

P28907-CD38_HUMAN
Tissue specificity: Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.

Evidence on tissue expression from TISSUES for CD38 Gene

  • Liver(4.6)
  • Pancreas(4.4)
  • Bone marrow(3.8)
  • Blood(3.7)
  • Lymph node(3.7)
  • Spleen(3.7)
  • Nervous system(3.1)
  • Heart(3)
  • Intestine(2.9)
  • Lung(2.8)
  • Muscle(2.7)
  • Skin(2.4)
  • Kidney(2.4)
  • Bone(2.3)
  • Urine(2.1)
  • Stomach(2)
genes like me logo Genes that share expression patterns with CD38: view

No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for CD38 Gene

Orthologs for CD38 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CD38 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia CD38 30 31
  • 99.33 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia CD38 30 31
  • 73.87 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Cd38 30
  • 72.75 (n)
Mouse
(Mus musculus)
Mammalia Cd38 30 17 31
  • 72.3 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia CD38 31
  • 47 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia CD38 31
  • 43 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia CD38 31
  • 42 (a)
OneToOne
Chicken
(Gallus gallus)
Aves CD38 30 31
  • 60.73 (n)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia cd38 30
  • 52.36 (n)
Zebrafish
(Danio rerio)
Actinopterygii LOC101886891 30
  • 48.65 (n)
CR318624.1 31
  • 30 (a)
OneToMany
Species where no ortholog for CD38 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for CD38 Gene

ENSEMBL:
Gene Tree for CD38 (if available)
TreeFam:
Gene Tree for CD38 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CD38: view image

Paralogs for CD38 Gene

Paralogs for CD38 Gene

(1) SIMAP similar genes for CD38 Gene using alignment to 2 proteins:

  • CD38_HUMAN
  • H0Y950_HUMAN
genes like me logo Genes that share paralogs with CD38: view

Variants for CD38 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CD38 Gene

SNP ID Clinical significance and condition Chr 04 pos Variation AA Info Type
744664 Likely Benign: not provided 15,840,467(+) T/G MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
790390 Benign: not provided 15,778,624(+) C/T NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
791971 Benign: not provided 15,838,170(+) A/G INTRON_VARIANT
rs1800561 - p.Arg140Trp

Additional dbSNP identifiers (rs#s) for CD38 Gene

Structural Variations from Database of Genomic Variants (DGV) for CD38 Gene

Variant ID Type Subtype PubMed ID
dgv5145n100 CNV gain 25217958
esv2676893 CNV deletion 23128226
esv3893885 CNV loss 25118596
nsv10460 CNV loss 18304495
nsv527861 CNV gain 19592680

Variation tolerance for CD38 Gene

Residual Variation Intolerance Score: 82.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.18; 23.72% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CD38 Gene

Human Gene Mutation Database (HGMD)
CD38
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CD38

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CD38 Gene

Disorders for CD38 Gene

MalaCards: The human disease database

(63) MalaCards diseases for CD38 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
richter's syndrome
  • richter syndrome
prolymphocytic leukemia
  • leukemia prolymphocytic
leukemia, chronic lymphocytic 2
  • leukemia, chronic lymphocytic, susceptibility to, 2
plasma cell leukemia
  • pcl
b cell prolymphocytic leukemia
  • leukemia, b cell prolymphocytic
- elite association - COSMIC cancer census association via MalaCards
Search CD38 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for CD38

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with CD38: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CD38 Gene

Publications for CD38 Gene

  1. A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro. (PMID: 9754820) Yagui K … Kanatsuka A (Diabetologia 1998) 3 4 23 41
  2. Human gene encoding CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase): organization, nucleotide sequence and alternative splicing. (PMID: 9074508) Nata K … Okamoto H (Gene 1997) 2 3 4 23
  3. Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation. (PMID: 2319135) Jackson DG … Bell JI (Journal of immunology (Baltimore, Md. : 1950) 1990) 2 3 4 23
  4. CD38 gene polymorphisms contribute to genetic susceptibility to B-cell chronic lymphocytic leukemia: evidence from two case-control studies in Polish Caucasians. (PMID: 19240243) Jamroziak K … Robak T (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009) 3 23 41
  5. CD38 gene polymorphism and chronic lymphocytic leukemia: a role in transformation to Richter syndrome? (PMID: 18424664) Aydin S … Deaglio S (Blood 2008) 3 23 41

Products for CD38 Gene

Sources for CD38 Gene