Aliases for CD37 Gene
External Ids for CD37 Gene
Previous GeneCards Identifiers for CD37 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for CD37 Gene
CD37 (CD37 Molecule) is a Protein Coding gene. Diseases associated with CD37 include Relapsed/Refractory Diffuse Large B-Cell Lymphoma and Osteogenesis Imperfecta, Type Iii. Among its related pathways are Hematopoietic cell lineage. An important paralog of this gene is CD82.