Aliases for CD37 Gene
External Ids for CD37 Gene
Previous GeneCards Identifiers for CD37 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for CD37 Gene
CD37 (CD37 Molecule) is a Protein Coding gene. Diseases associated with CD37 include Osteogenesis Imperfecta, Type Iii and Leukemia, Chronic Lymphocytic. Among its related pathways are Hematopoietic cell lineage. An important paralog of this gene is CD82.