Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CD300H Gene

Aliases for CD300H Gene

  • CD300H Molecule (Gene/Pseudogene) 2 3
  • CD300c Molecule-Like 3
  • AC079325.2 5
  • CD300Hs 3

External Ids for CD300H Gene

Summaries for CD300H Gene

Entrez Gene Summary for CD300H Gene

  • This gene belongs to the CD300 gene family, which in turn, belongs to the immunoglobulin (Ig) superfamily. This gene is located within a CD300 cluster on chromosome 17. The encoded protein may be involved in innate immunity as well as autoimmune response. A G>A mutation, represented by the single nucleotide polymorphism (SNP) rs905709, at the splice donor site of the 5' terminal exon may be associated with lack of expression of this gene in homozygous (AA) individuals. The human reference assembly (GRCh38.p2) represents the 'A' allele at this SNP. [provided by RefSeq, Apr 2016]

GeneCards Summary for CD300H Gene

CD300H (CD300H Molecule (Gene/Pseudogene)) is a Protein Coding gene. An important paralog of this gene is CD300C.

Additional gene information for CD300H Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CD300H Gene

Genomics for CD300H Gene

GeneHancer (GH) Regulatory Elements for CD300H Gene

Promoters and enhancers for CD300H Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J074566 Enhancer 0.8 Ensembl dbSUPER 650.7 +0.9 933 0.4 CTCF TRIM22 KLF14 RAD21 ZFHX2 ZNF143 ZNF444 EGR2 CD300H LOC101928343 CD300C CD300LB CD300LD CD300E GPR142 CD300A ENSG00000236770
GH17J074569 Enhancer 0.7 ENCODE dbSUPER 650.7 +1.2 1203 0 CTCF XRCC5 TRIM22 ZNF143 ZNF444 KLF14 RAD21 CD300H CD300LB CD300LD CD300E GPR142 ENSG00000236770
GH17J074567 Enhancer 0.5 Ensembl dbSUPER 650.7 +0.1 54 0.6 ZNF189 CD300H CD300C LOC101928343 CD300LB CD300LD CD300E RAB37 ENSG00000236770
GH17J074568 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.7 -2.0 -2022 1.5 ZNF473 ZSCAN4 SIN3A ZNF195 YBX1 GLI4 EGR1 FOS EGR2 YY2 CD300E NAT9 CD300C NUP85 CD300LB NT5C ENSG00000266765 LINC02092 ENSG00000265927 ENSG00000265935
GH17J074557 Enhancer 0.4 dbSUPER 0.4 +9.0 8970 1.9 NANOG POU5F1 CD300C ENSG00000236770 CD300LB CD300LD CD300E GPR142 LOC101928343 CD300H
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CD300H on UCSC Golden Path with GeneCards custom track

Genomic Locations for CD300H Gene

Genomic Locations for CD300H Gene
chr17:74,557,246-74,567,534
(GRCh38/hg38)
Size:
10,289 bases
Orientation:
Minus strand

Genomic View for CD300H Gene

Genes around CD300H on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CD300H Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CD300H Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CD300H Gene

Proteins for CD300H Gene

  • Protein details for CD300H Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A286YF48-A0A286YF48_HUMAN
    Recommended name:
    Uncharacterized protein
    Protein Accession:
    A0A286YF48

    Protein attributes for CD300H Gene

    Size:
    153 amino acids
    Molecular mass:
    16390 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CD300H Gene

Post-translational modifications for CD300H Gene

No Post-translational modifications

Other Protein References for CD300H Gene

No data available for DME Specific Peptides for CD300H Gene

Domains & Families for CD300H Gene

Protein Domains for CD300H Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CD300H: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CD300H Gene

Function for CD300H Gene

Gene Ontology (GO) - Molecular Function for CD300H Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI --
genes like me logo Genes that share ontologies with CD300H: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CD300H Gene

Localization for CD300H Gene

Gene Ontology (GO) - Cellular Components for CD300H Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CD300H: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for CD300H Gene

Pathways & Interactions for CD300H Gene

SuperPathways for CD300H Gene

No Data Available

Interacting Proteins for CD300H Gene

Gene Ontology (GO) - Biological Process for CD300H Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030593 neutrophil chemotaxis IDA --
genes like me logo Genes that share ontologies with CD300H: view

No data available for Pathways by source and SIGNOR curated interactions for CD300H Gene

Drugs & Compounds for CD300H Gene

No Compound Related Data Available

Transcripts for CD300H Gene

mRNA/cDNA for CD300H Gene

(4) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CD300H Gene

No ASD Table

Relevant External Links for CD300H Gene

GeneLoc Exon Structure for
CD300H
ECgene alternative splicing isoforms for
CD300H

Expression for CD300H Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CD300H Gene

Orthologs for CD300H Gene

This gene was present in the common ancestor of mammals.

Orthologs for CD300H Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia LOC100686047 33
  • 80.57 (n)
cow
(Bos Taurus)
Mammalia LOC614141 33
  • 74.81 (n)
Species where no ortholog for CD300H was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CD300H Gene

ENSEMBL:
Gene Tree for CD300H (if available)
TreeFam:
Gene Tree for CD300H (if available)

Paralogs for CD300H Gene

Paralogs for CD300H Gene

genes like me logo Genes that share paralogs with CD300H: view

Variants for CD300H Gene

Sequence variations from dbSNP and Humsavar for CD300H Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000143552 -- 74,559,438(-) T/A genic_downstream_transcript_variant, intron_variant
rs1000405486 -- 74,559,035(-) T/C genic_downstream_transcript_variant, intron_variant
rs1000789640 -- 74,564,425(-) G/A intron_variant
rs1001315162 -- 74,558,545(-) C/T genic_downstream_transcript_variant, intron_variant
rs1001397995 -- 74,563,073(-) G/A intron_variant

Additional Variant Information for CD300H Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CD300H

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for CD300H Gene

Disorders for CD300H Gene

Additional Disease Information for CD300H

No disorders were found for CD300H Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CD300H Gene

Publications for CD300H Gene

  1. Identification and Characterization of CD300H, a New Member of the Human CD300 Immunoreceptor Family. (PMID: 26221034) Niizuma K … Shibuya A (The Journal of biological chemistry 2015) 2 3 58

Products for CD300H Gene

Sources for CD300H Gene

Content
Loading form....