Aliases for CD27 Gene
Aliases for CD27 Gene
External Ids for CD27 Gene
- HGNC: 11922
- Entrez Gene: 939
- Ensembl: ENSG00000139193
- OMIM: 186711
- UniProtKB: P26842
Previous HGNC Symbols for CD27 Gene
- TNFRSF7
Previous GeneCards Identifiers for CD27 Gene
- GC12P006554
Summaries for CD27 Gene
-
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
GeneCards Summary for CD27 Gene
CD27 (CD27 Molecule) is a Protein Coding gene. Diseases associated with CD27 include Lymphoproliferative Syndrome 2 and Autosomal Recessive Lymphoproliferative Disease. Among its related pathways are Cytokine Signaling in Immune system and Akt Signaling. Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity and cysteine-type endopeptidase inhibitor activity involved in apoptotic process.
UniProtKB/Swiss-Prot for CD27 Gene
-
Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Additional gene information for CD27 Gene
- Monarch Initiative
- Search for CD27 at DataMed
- Search for CD27 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CD27 Gene
Genomics for CD27 Gene
GeneHancer (GH) Regulatory Elements for CD27 Gene
Promoters and enhancers for CD27 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CD27 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CD27 gene promoter:
Regulatory Element Products
Genomic Locations for CD27 Gene
Genomic Locations for CD27 Gene
- chr12:6,444,867-6,451,718
- (GRCh38/hg38)
- Size:
- 6,852 bases
- Orientation:
- Plus strand
- chr12:6,554,033-6,560,884
- (GRCh37/hg19)
Genomic View for CD27 Gene
Genes around CD27 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p13.31 by Ensembl
- 12p13.31 by Entrez Gene
- 12p13.31 by HGNC
CD27 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CD27 Gene
Proteins for CD27 Gene
-
Protein details for CD27 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P26842-CD27_HUMAN
- Recommended name:
- CD27 antigen
- Protein Accession:
- P26842
- B2RDZ0
Protein attributes for CD27 Gene
- Size:
- 260 amino acids
- Molecular mass:
- 29137 Da
- Quaternary structure:
-
- Homodimer. Interacts with SIVA1 and TRAF2.
Protein Expression for CD27 Gene
Post-translational modifications for CD27 Gene
- O-glycosylated with core 1 or possibly core 8 glycans.
- Phosphorylated.
- Glycosylation at posLast=9595 and Ser127
- Modification sites at PhosphoSitePlus
Other Protein References for CD27 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CD27 (CD27/TNFRSF7)
-
Custom Antibody ServicesOriGene Antibodies for CD27
- Novus Biologicals Antibodies for CD27
-
Abcam antibodies for CD27
-
Cloud-Clone Corp. Antibodies for CD27
- Invitrogen Antibodies for CD27
- antibodies-online: Search results for 538 available CD27 Antibodies ranked by validation data
- Compare Top CD27 Antibodies
-
Recommended
- 2 IHC Antibodies (anti-rat)
- 7 IP Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 17 WB Antibodies (anti-rat)
- 29 FACS Antibodies (anti-rat)
- 1 IHC (fro) Antibody (anti-human)
- 1 BCA Antibody (anti-human)
- 2 RIA Antibodies (anti-human)
- 6 ICFC Antibodies (anti-human)
- 10 IF Antibodies (anti-human)
- 12 IHC Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 20 IP Antibodies (anti-human)
- 41 IHC (p) Antibodies (anti-human)
- 80 WB Antibodies (anti-human)
- 238 FACS Antibodies (anti-human)
- 1 IF/ICC Antibody (anti-mouse)
- 1 ICC Antibody (anti-mouse)
- 2 IHC (fro) Antibodies (anti-mouse)
- 9 IHC Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 15 IP Antibodies (anti-mouse)
- 18 WB Antibodies (anti-mouse)
- 20 IHC (p) Antibodies (anti-mouse)
- 84 FACS Antibodies (anti-mouse)
- GeneTex CD27 antibody for CD27
-
Custom Antibody ServicesProSci Antibodies for CD27
-
Santa Cruz Biotechnology (SCBT) Antibodies for CD27
- Sino Biological Antibodies for CD27
Protein Products
- R&D Systems Proteins and Enzymes for CD27 (CD27/TNFRSF7)
-
OriGene Purified Proteins for CD27
- Search Origene for MassSpec and Protein Over-expression Lysates for CD27
- Origene Custom Protein Services for CD27
- Sino Biological Recombinant Proteins for CD27
- Sino Biological Cell Lysates for CD27
- ProSpec Recombinant Proteins for CD27
-
Cloud-Clone Corp. Proteins for CD27
- Search GeneTex for Proteins for CD27
-
ProSci Proteins for CD27
-
Abcam proteins for CD27
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for CD27
- R&D Systems ELISAs, Luminex Assays, and other biochemical assays for CD27 (CD27/TNFRSF7)
-
Cloud-Clone Corp. Assay Kits for CD27
-
Abcam assays for CD27
No data available for DME Specific Peptides for CD27 Gene
Domains & Families for CD27 Gene
Gene Families for CD27 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- CD markers
- Disease related genes
- Plasma proteins
- Predicted membrane proteins
Protein Domains for CD27 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CD27 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for CD27 Gene
Function for CD27 Gene
Molecular function for CD27 Gene
- UniProtKB/Swiss-Prot Function:
- Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Phenotypes From GWAS Catalog for CD27 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004888 | transmembrane signaling receptor activity | NAS | 14556986 |
| GO:0005031 | tumor necrosis factor-activated receptor activity | IBA | -- |
| GO:0005515 | protein binding | IPI | 9177220 |
| GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process | IDA | 12324477 |
Phenotypes for CD27 Gene
- MGI mutant phenotypes for CD27:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CD27:
Animal Models for CD27 Gene
- MGI Knock Outs for CD27:
-
- Cd27 tm1Jbo
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CD27
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CD27 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CD27 gene
- Search ViGene Biosciences for CD27
CRISPR Products
-
OriGene CRISPR knockouts for CD27
- genomics-online: gRNA clones - Search results for 166 available CD27 gene related products
- Overview of 166 available CD27 gene related products
- Applied Biological Materials CRISPR for CD27
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CD27
- GenScript: Design CRISPR guide RNA sequences for CD27
miRNA for CD27 Gene
- miRTarBase miRNAs that target CD27
miRNA Products
- Search ViGene Biosciences for CD27
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CD27
- Browse OriGene Inhibitory RNA Products For CD27
- genomics-online: shRNA clones - Search results for 166 available CD27 gene related products
- Overview of 166 available CD27 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CD27 gene
Clone Products
- Sino Biological Human cDNA Clone for CD27
- VectorBuilder custom plasmid, inducible vectors for CD27
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD27
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for CD27
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for CD27 (CD27/TNFRSF7)
Cell Line Products
-
Horizon Cell Lines for CD27
-
ViGene Biosciences adenoviral particle packaged cDNA for CD27 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CD27 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CD27 gene
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for CD27 Gene
Localization for CD27 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CD27 Gene
- Membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| cytosol | 2 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | NAS | 12624711 |
| GO:0005622 | intracellular | IEA | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | IBA,NAS | 12324477 |
| GO:0009897 | external side of plasma membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CD27 Gene
Pathways & Interactions for CD27 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Akt Signaling |
.60
.60
|
|
| 2 | PEDF Induced Signaling |
.47
|
|
| 3 | B Cell Development Pathways | ||
| 4 | T Cell Co-Signaling Pathway: Ligand-Receptor Interactions | ||
| 5 | PAK Pathway | ||
Pathways by source for CD27 Gene
4 Reactome pathways for CD27 Gene
1 KEGG pathway for CD27 Gene
1 GeneGo (Thomson Reuters) pathway for CD27 Gene
2 R&D Systems pathways for CD27 Gene
8 Qiagen pathways for CD27 Gene
Interacting Proteins for CD27 Gene
Selected Interacting proteins:
ENSP00000266557
P26842-CD27_HUMAN
for CD27 Gene via
STRING
UniProtKB
IID
SIGNOR curated interactions for CD27 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006915 | apoptotic process | IEA | -- |
| GO:0006954 | inflammatory response | IBA | -- |
| GO:0006955 | immune response | IBA | -- |
| GO:0007166 | cell surface receptor signaling pathway | NAS | 14556986 |
| GO:0007275 | multicellular organism development | IBA | -- |
Transcripts for CD27 Gene
mRNA/cDNA for CD27 Gene
- (5) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (4) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CD27
- genomics-online: gRNA clones - Search results for 166 available CD27 gene related products
- Overview of 166 available CD27 gene related products
- Applied Biological Materials CRISPR for CD27
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CD27
- GenScript: Design CRISPR guide RNA sequences for CD27
miRNA Products
- Search ViGene Biosciences for CD27
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CD27
- Browse OriGene Inhibitory RNA Products For CD27
- genomics-online: shRNA clones - Search results for 166 available CD27 gene related products
- Overview of 166 available CD27 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CD27 gene
Clone Products
- Sino Biological Human cDNA Clone for CD27
- VectorBuilder custom plasmid, inducible vectors for CD27
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD27
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for CD27
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for CD27 (CD27/TNFRSF7)
Expression for CD27 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Cardiovascular System)
- T-Cytotoxic Cells Thymus
- Hematopoietic Bone Marrow
- Double Positive Thymocytes Thymus
- Hematopoietic Stem Cells Liver Bud
- T Helper Cells Thymus
-
Thymus (Hematopoietic System)
- Thymus
- T-Cytotoxic Cells Thymus
- Double Positive Thymocytes Thymus
- T Helper Cells Thymus
-
Liver (Hepatobiliary System)
- Hematopoietic Stem Cells Liver Bud
-
Spleen (Hematopoietic System)
-
Tonsil (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for CD27 Gene
This gene is overexpressed in Spleen (x9.2), Whole Blood (x7.4), and Small Intestine - Terminal Ileum (x4.6).
This gene is overexpressed in Urine (31.2), Peripheral blood mononuclear cells (17.9), and Blymphocyte (9.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CD27 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CD27 Gene:
CD27SOURCE GeneReport for Unigene cluster for CD27 Gene:
Hs.355307mRNA Expression by UniProt/SwissProt for CD27 Gene:
P26842-CD27_HUMAN
Tissue specificity:
Found in most T-lymphocytes.
Evidence on tissue expression from TISSUES for CD27 Gene
- Blood(4.8)
- Lymph node(3.5)
- Spleen(3.3)
- Bone marrow(2.8)
- Intestine(2.7)
- Nervous system(2.6)
Phenotype-based relationships between genes and organs from Gene ORGANizer for CD27 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- immune
- lymphatic
- nervous
Regions:
Head and neck:
- brain
- head
- mouth
Abdomen:
- liver
- spleen
General:
- blood
- bone marrow
- coagulation system
- lymph node
- red blood cell
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for CD27
-
OriGene qPCR primer pairs and template standards for CD27
- genomics-online: primer clones - Search results for 166 available CD27 gene related products
- Overview of 166 available CD27 gene related products
Gene Expression Assay Products
Orthologs for CD27 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CD27 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | CD27 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | CD27 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cd27 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Cd27 33 16 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CD27 34 |
|
OneToOne |
- Species where no ortholog for CD27 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for CD27 Gene
No data available for Paralogs for CD27 Gene
Variants for CD27 Gene
| SNP ID | Clin | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs11830902 | benign, Lymphoproliferative syndrome 2 | 6,450,164(+) | T/C | intron_variant | |
| rs2532502 | benign, Lymphoproliferative syndrome 2, not specified | 6,451,307(+) | A/G/T | coding_sequence_variant, missense_variant, synonymous_variant | |
| rs34540052 | benign, Lymphoproliferative syndrome 2 | 6,445,125(+) | C/A/T | coding_sequence_variant, genic_upstream_transcript_variant, stop_gained, synonymous_variant, upstream_transcript_variant | |
| rs397514667 | pathogenic, Lymphoproliferative syndrome 2, Lymphoproliferative syndrome 2 (LPFS2) [MIM:615122] | 6,445,445(+) | G/A | coding_sequence_variant, genic_upstream_transcript_variant, missense_variant, upstream_transcript_variant | |
| rs398122933 | pathogenic, Lymphoproliferative syndrome 2 | 6,445,119(+) | G/A | coding_sequence_variant, genic_upstream_transcript_variant, stop_gained, upstream_transcript_variant |
Residual Variation Intolerance Score:
31% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.40;
77.11% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CD27 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CD27 Gene
Disorders for CD27 Gene
(21) MalaCards diseases for CD27 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| lymphoproliferative syndrome 2 |
|
|
| autosomal recessive lymphoproliferative disease |
|
|
| lymphoproliferative syndrome |
|
|
| precursor b lymphoblastic lymphoma/leukemia |
|
|
| pars planitis |
|
|
Search CD27 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
CD27_HUMAN- Lymphoproliferative syndrome 2 (LPFS2) [MIM:615122]: An autosomal recessive immunodeficiency disorder associated with persistent symptomatic EBV viremia, hypogammaglobulinemia, and impaired T-cell-dependent B-cell responses and T-cell dysfunction. The phenotype is highly variable, ranging from asymptomatic borderline-low hypogammaglobulinemia, to a full-blown symptomatic systemic inflammatory response with life-threatening EBV-related complications, including hemophagocytic lymphohistiocytosis, a lymphoproliferative disorder, and malignant lymphoma requiring stem cell transplantation. {ECO:0000269 PubMed:22197273, ECO:0000269 PubMed:22801960}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for CD27
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for CD27 Gene
Publications for CD27 Gene
- Isolation and regional assignment of human chromosome 12p cDNAs. (PMID: 8530100) Baens M … Marynen P (Genomics 1995) 2 3 22 58
- Genomic organization and chromosomal localization of the human CD27 gene. (PMID: 1334106) Loenen WA … Borst J (Journal of immunology (Baltimore, Md. : 1950) 1992) 3 4 22 58
- The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family. (PMID: 1655907) Camerini D … Seed B (Journal of immunology (Baltimore, Md. : 1950) 1991) 3 4 22 58
- Combined immunodeficiency with life-threatening EBV-associated lymphoproliferative disorder in patients lacking functional CD27. (PMID: 22801960) Salzer E … Seidel MG (Haematologica 2013) 3 4 58
- CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia. (PMID: 22197273) van Montfrans JM … Tesselaar K (The Journal of allergy and clinical immunology 2012) 3 4 58
Products for CD27 Gene
- R&D Systems Antibodies for CD27 (CD27/TNFRSF7)
- R&D Systems Proteins and Enzymes for CD27 (CD27/TNFRSF7)
- R&D Systems ELISAs, Luminex Assays, and other biochemical assays for CD27 (CD27/TNFRSF7)
- R&D Systems cDNA Clones for CD27 (CD27/TNFRSF7)
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for CD27
- Custom Assay ServicesOriGene ELISA Kits for CD27
- OriGene Purified Proteins for CD27
- Search Origene for MassSpec and Protein Over-expression Lysates for CD27
- Origene Custom Protein Services for CD27
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CD27
- Browse OriGene Inhibitory RNA Products For CD27
- OriGene qPCR primer pairs and template standards for CD27
- OriGene qPCR primer pairs for CD27
- OriGene CRISPR knockouts for CD27
- OriGene ORF clones in human for CD27
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CD27
- GenScript: Next-day shipping of latest version cDNA ORF clones for CD27 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CD27
- GenScript Custom Assay Services for CD27
- GenScript Custom overexpressing Cell Line Services for CD27
- GenScript: Design CRISPR guide RNA sequences for CD27
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CD27
- Sino Biological Human cDNA Clone for CD27
- Sino Biological Recombinant Proteins for CD27
- Sino Biological Cell Lysates for CD27
- Sino Biological Antibodies for CD27
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for CD27
- Novus Biologicals lysates and proteins for CD27
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for CD27
- Abcam proteins for CD27
- Abcam assays for CD27
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for CD27
- Cloud-Clone Corp. Antibodies for CD27
- Cloud-Clone Corp. Proteins for CD27
- Cloud-Clone Corp. Assay Kits for CD27
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for CD27
- VectorBuilder custom plasmid, inducible vectors for CD27
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD27
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 538 available CD27 Antibodies ranked by validation data
- Compare Top CD27 Antibodies
- Recommended
- 84 FACS Antibodies (anti-mouse)
- 20 IHC (p) Antibodies (anti-mouse)
- 18 WB Antibodies (anti-mouse)
- 15 IP Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 9 IHC Antibodies (anti-mouse)
- 2 IHC (fro) Antibodies (anti-mouse)
- 1 ICC Antibody (anti-mouse)
- 1 IF/ICC Antibody (anti-mouse)
- 238 FACS Antibodies (anti-human)
- 80 WB Antibodies (anti-human)
- 41 IHC (p) Antibodies (anti-human)
- 20 IP Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 12 IHC Antibodies (anti-human)
- 10 IF Antibodies (anti-human)
- 6 ICFC Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 1 BCA Antibody (anti-human)
- 1 IHC (fro) Antibody (anti-human)
- 29 FACS Antibodies (anti-rat)
- 17 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 7 IP Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
- antibodies-online: Search results for 24 available CD27 Elisa Kits ranked by validation data
- Compare Top CD27 Elisa Kits
- antibodies-online: Search results for 28 available CD27 Proteins ranked by validation data
- Compare Top CD27 Proteins
- GeneTex CD27 antibody for CD27
- Search GeneTex for Proteins for CD27
- ViGene Biosciences adenoviral particle packaged cDNA for CD27 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CD27 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CD27 gene
- Search ViGene Biosciences for CD27
- Santa Cruz Biotechnology (SCBT) Antibodies for CD27
- Search Santa Cruz Biotechnology (SCBT) for CD27 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CD27
- Custom Antibody ServicesProSci Antibodies for CD27
- ProSci Proteins for CD27
- Horizon Cell Lines for CD27
- genomics-online: cdna clones - Search results for 166 available CD27 gene related products
- Overview of 166 available CD27 gene related products
- orf clones - Search results for 166 available CD27 gene related products
- Overview of 166 available CD27 gene related products
- genomics-online: gRNA clones - Search results for 166 available CD27 gene related products
- Overview of 166 available CD27 gene related products
- genomics-online: primer clones - Search results for 166 available CD27 gene related products
- Overview of 166 available CD27 gene related products
- genomics-online: shRNA clones - Search results for 166 available CD27 gene related products
- Overview of 166 available CD27 gene related products
Sources for CD27 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems