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CD248 (CD248 Molecule) is a Protein Coding gene. Diseases associated with CD248 include Vascular Cancer and Adult Fibrosarcoma. Gene Ontology (GO) annotations related to this gene include calcium ion binding and extracellular matrix binding. An important paralog of this gene is CD93.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003674 | molecular_function | ND | -- |
GO:0005509 | calcium ion binding | IEA | -- |
GO:0030246 | carbohydrate binding | IEA | -- |
GO:0050840 | extracellular matrix binding | IEA,IBA | 21873635 |
GO:1990430 | extracellular matrix protein binding | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IEA | -- |
GO:0009897 | external side of plasma membrane | IBA | 21873635 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO:0031012 | extracellular matrix | TAS | 10947988 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0008150 | biological_process | ND | -- |
GO:0008284 | positive regulation of cell proliferation | IEA | -- |
GO:0016477 | cell migration | IEA,IBA | 21873635 |
GO:0048535 | lymph node development | IEA | -- |
GO:0060033 | anatomical structure regression | IEA | -- |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
MORAB-004 | Pharma | 0 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | CD248 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | CD248 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | CD248 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Cd248 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Cd248 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | CD248 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | CD248 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | cd248b 31 |
|
OneToMany | |
cd248a 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
707881 | Benign: not provided | 66,315,321(-) | G/C | SYNONYMOUS_VARIANT | |
707892 | Benign: not provided | 66,316,725(-) | G/A | SYNONYMOUS_VARIANT | |
718523 | Benign: not provided | 66,315,792(-) | C/T | SYNONYMOUS_VARIANT | |
721839 | Benign: not provided | 66,314,997(-) | G/A | SYNONYMOUS_VARIANT | |
730132 | Likely Benign: not provided | 66,315,269(-) | T/G | MISSENSE_VARIANT |
Disorder | Aliases | PubMed IDs |
---|---|---|
vascular cancer |
|
|
adult fibrosarcoma |
|
|
acute cystitis |
|
|
granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type iii |
|
|
granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type i |
|
|