Aliases for CD2-LCR Gene
External Ids for CD2-LCR Gene
- Entrez Gene: 107126361
This element represents a locus control region (LCR) that can confer T cell-specific, copy number-dependent, position-independent expression on the CD2 gene in transgenic mice. It is located immediately downstream of the 3' terminal exon of the CD2 gene, and is characterized by three DNase I hypersensitive sites and a core enhancer region. This LCR and the enhancer sub-region have been used to drive T cell-specific expression of several heterologous genes in various vector systems, including retroviral and lentiviral vectors. A truncated version of the LCR has been shown to be heterochromatin-sensitive, and has thus been useful for studying chromatin-related processes, such as triplet-repeat-associated position effect variegation. [provided by RefSeq, Jan 2016]
GeneCards Summary for CD2-LCR Gene
CD2-LCR (CD2 Locus Control Region) is an Uncategorized gene.