Aliases for CD1B Gene
Aliases for CD1B Gene
External Ids for CD1B Gene
- HGNC: 1635
- Entrez Gene: 910
- Ensembl: ENSG00000158485
- OMIM: 188360
- UniProtKB: P29016
Previous HGNC Symbols for CD1B Gene
- CD1
Previous GeneCards Identifiers for CD1B Gene
- GC01M156089
- GC01M154030
- GC01M155075
- GC01M155514
- GC01M155110
- GC01M156564
- GC01M129655
Summaries for CD1B Gene
-
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008]
GeneCards Summary for CD1B Gene
CD1B (CD1b Molecule) is a Protein Coding gene. Diseases associated with CD1B include Mycobacterium Malmoense and Mycobacterium Tuberculosis 1. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Tight junction. Gene Ontology (GO) annotations related to this gene include beta-2-microglobulin binding and endogenous lipid antigen binding. An important paralog of this gene is CD1C.
UniProtKB/Swiss-Prot for CD1B Gene
-
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CD1B Gene
Genomics for CD1B Gene
GeneHancer (GH) Regulatory Elements for CD1B Gene
Promoters and enhancers for CD1B Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH01J158331 | Promoter/Enhancer | 0.7 | EPDnew dbSUPER | 650.7 | 0.0 | -20 | 0.1 | CD1B CD1E | ||
| GH01J158335 | Enhancer | 0.5 | Ensembl dbSUPER | 650.7 | -2.0 | -1970 | 0.2 | SRF | CD1B CD1E | |
| GH01J158283 | Promoter/Enhancer | 2 | EPDnew FANTOM5 Ensembl ENCODE dbSUPER | 10.1 | +43.4 | 43413 | 9.8 | HDGF PKNOX1 RB1 STAT5A BMI1 BATF KLF5 IRF4 ZNF143 ATF7 | CD1C GC01P158286 CD1B CD1E GC01P158293 GC01P158292 | |
| GH01J158247 | Promoter/Enhancer | 1.8 | EPDnew FANTOM5 Ensembl ENCODE dbSUPER | 3.8 | +82.8 | 82830 | 2.2 | SRF CBFB MAX POLR2A SCRT2 IKZF1 EED ETV6 MLLT1 MYC | CD1A CD1C CD1E CD1D CD1B OR10T2 GC01P158260 GC01P158261 | |
| GH01J158333 | Enhancer | 0.5 | FANTOM5 dbSUPER | 8.2 | -2.4 | -2449 | 0.2 | CD1E CD1B OR6Y1 OR10K2 OR6K6 OR10T2 CD1C |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around CD1B on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CD1B gene promoter:
-
- MRF-2
- CREB
- deltaCREB
- LCR-F1
- SREBP-1a
- SREBP-1b
- SREBP-1c
Regulatory Element Products
Genomic Locations for CD1B Gene
Genomic Locations for CD1B Gene
- chr1:158,327,950-158,331,531
- (GRCh38/hg38)
- Size:
- 3,582 bases
- Orientation:
- Minus strand
- chr1:158,297,740-158,301,321
- (GRCh37/hg19)
- Size:
- 3,582 bases
- Orientation:
- Minus strand
Genomic View for CD1B Gene
Genes around CD1B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q23.1 by Entrez Gene
- 1q23.1 by HGNC
- 1q23.1 by Ensembl
CD1B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CD1B Gene
Proteins for CD1B Gene
-
Protein details for CD1B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P29016-CD1B_HUMAN
- Recommended name:
- T-cell surface glycoprotein CD1b
- Protein Accession:
- P29016
- Q5TDK9
- Q5TDL0
- Q9UMM2
Protein attributes for CD1B Gene
- Size:
- 333 amino acids
- Molecular mass:
- 36939 Da
- Quaternary structure:
-
- Heterodimer with B2M (beta-2-microglobulin). Interacts with saposin C.
- Miscellaneous:
-
- During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes or lysosomes, before trafficking back to the cell surface. Interaction with saposin C is required for the loading of bacterial lipid antigens onto CD1B in the lysosome.
- SequenceCaution:
-
- Sequence=CAI10852.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for CD1B Gene
Protein Expression for CD1B Gene
Post-translational modifications for CD1B Gene
Other Protein References for CD1B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CD1B (CD1b)
- Novus Biologicals Antibodies for CD1B
- Invitrogen Antibodies for CD1B
- GeneTex CD1B Antibody for CD1B
-
Santa Cruz Biotechnology (SCBT) Antibodies for CD1B
Protein Products
-
OriGene Purified Proteins for CD1B
- Search Origene for MassSpec and Protein Over-expression Lysates for CD1B
- Origene Custom Protein Services for CD1B
- Sino Biological Recombinant Proteins for CD1B
- Sino Biological Cell Lysates for CD1B
- ProSpec Recombinant Proteins for CD1B
- Search GeneTex for Proteins for CD1B
-
Abcam proteins for CD1B
Assay Products
- antibodies-online: Search results for 1 available CD1b Elisa Kits ranked by validation data
- Compare Top CD1b Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for CD1B Gene
Domains & Families for CD1B Gene
Gene Families for CD1B Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- CD markers
- Predicted membrane proteins
Protein Domains for CD1B Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CD1B Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for CD1B Gene
Function for CD1B Gene
Molecular function for CD1B Gene
- UniProtKB/Swiss-Prot Function:
- Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
- GENATLAS Biochemistry:
- cell differentiation antigen CD1B,45kDa,membrane glycoprotein,B2M associated,identified by monoclonal antibodies WM-25,4A76,NUT2 (see CD1@)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 12118248 |
| GO:0030881 | beta-2-microglobulin binding | IBA | -- |
| GO:0030883 | endogenous lipid antigen binding | IBA | -- |
| GO:0030884 | exogenous lipid antigen binding | IBA | -- |
| GO:0071723 | lipopeptide binding | IBA | -- |
Phenotypes for CD1B Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CD1B
-
CRISPR Products
-
OriGene CRISPR knockouts for CD1B
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- genomics-online: gRNA clones - Search results for 55 available CD1b gene related products
- Overview of 55 available CD1b gene related products
- Applied Biological Materials CRISPR for CD1B
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CD1B
- GenScript: Design CRISPR guide RNA sequences for CD1B
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CD1B
- Browse OriGene Inhibitory RNA Products For CD1B
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- genomics-online: shRNA clones - Search results for 55 available CD1b gene related products
- Overview of 55 available CD1b gene related products
Clone Products
- Sino Biological Human cDNA Clone for CD1B
- VectorBuilder custom plasmid, inducible vectors for CD1B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD1B
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CD1B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CD1B
- Applied Biological Materials Clones for CD1B
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for CD1B (CD1b)
Cell Line Products
-
Horizon Cell Lines for CD1B
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CD1B Gene
Localization for CD1B Gene
Subcellular locations from UniProtKB/Swiss-Prot for CD1B Gene
- Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. {ECO:0000269 PubMed:10899914, ECO:0000269 PubMed:10981968, ECO:0000269 PubMed:14716313}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| lysosome | 4 |
| endosome | 4 |
| extracellular | 2 |
| peroxisome | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005764 | lysosome | IEA | -- |
| GO:0005765 | lysosomal membrane | IEA | -- |
| GO:0005768 | endosome | IEA | -- |
| GO:0005886 | plasma membrane | IBA,TAS | -- |
| GO:0009986 | cell surface | HDA | 23981064 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CD1B Gene
Pathways & Interactions for CD1B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Hematopoietic cell lineage | ||
| 2 | Tight junction | ||
| 3 | Class I MHC mediated antigen processing and presentation | ||
| 4 | Innate Immune System |
.61
|
|
| 5 | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | ||
Pathways by source for CD1B Gene
3 Reactome pathways for CD1B Gene
2 KEGG pathways for CD1B Gene
Interacting Proteins for CD1B Gene
Selected Interacting proteins:
ENSP00000357150
P29016-CD1B_HUMAN
for CD1B Gene via
STRING
IID
UniProtKB
GPS-Prot Interaction Network for CD1B
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002250 | adaptive immune response | IEA | -- |
| GO:0002376 | immune system process | IEA | -- |
| GO:0048007 | antigen processing and presentation, exogenous lipid antigen via MHC class Ib | IBA | -- |
| GO:0050776 | regulation of immune response | TAS | -- |
No data available for SIGNOR curated interactions for CD1B Gene
Drugs & Compounds for CD1B Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| 3-Dehydrosphinganine |
|
16105-69-4 |
|
|||
| 3-O-Sulfogalactosylceramide (d18:1/12:0) |
|
852100-88-0 |
|
|||
| 3-O-Sulfogalactosylceramide (d18:1/14:0) |
|
|
||||
| 3-O-Sulfogalactosylceramide (d18:1/16:0) |
|
862509-48-6 |
|
|||
| 3-O-Sulfogalactosylceramide (d18:1/18:0) |
|
244215-65-4 |
|
Drug Products
Transcripts for CD1B Gene
mRNA/cDNA for CD1B Gene
- (5) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (22) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000451207 1024 bps (uc057mfi.1)
- ENST00000368168 1395 bps (uc001frx.4)
CRISPR Products
-
OriGene CRISPR knockouts for CD1B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CD1B
- genomics-online: gRNA clones - Search results for 55 available CD1b gene related products
- Overview of 55 available CD1b gene related products
- Applied Biological Materials CRISPR for CD1B
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CD1B
- GenScript: Design CRISPR guide RNA sequences for CD1B
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CD1B
- Browse OriGene Inhibitory RNA Products For CD1B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CD1B
- genomics-online: shRNA clones - Search results for 55 available CD1b gene related products
- Overview of 55 available CD1b gene related products
Clone Products
- Sino Biological Human cDNA Clone for CD1B
- VectorBuilder custom plasmid, inducible vectors for CD1B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD1B
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CD1B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CD1B
- Applied Biological Materials Clones for CD1B
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for CD1B (CD1b)
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||
| SP2: | |||||||||||||||||
| SP3: |
Expression for CD1B Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Monocytes Peripheral Blood
- Double Negative 2 Thymocytes Thymus
- Double Negative 3 Thymocytes Thymus
-
Thymus (Hematopoietic System)
- Double Negative 2 Thymocytes Thymus
- Double Negative 3 Thymocytes Thymus
mRNA differential expression in normal tissues according to GTEx for CD1B Gene
This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (x6.5), Spleen (x4.9), and Whole Blood (x4.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CD1B Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CD1B Gene:
CD1BSOURCE GeneReport for Unigene cluster for CD1B Gene:
Hs.1310mRNA Expression by UniProt/SwissProt for CD1B Gene:
P29016-CD1B_HUMAN
Tissue specificity:
Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
Evidence on tissue expression from TISSUES for CD1B Gene
- Lung(4.2)
- Blood(2.9)
- Lymph node(2.4)
- Spleen(2.2)
- Skin(2)
Primer Products
-
OriGene qPCR primer pairs for CD1B
- genomics-online: primer clones - Search results for 55 available CD1b gene related products
- Overview of 55 available CD1b gene related products
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CD1B Gene
Orthologs for CD1B Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CD1B 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | CD1B5 34 33 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| CD1B3 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | CD1B 34 33 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CD1A1 34 |
|
ManyToMany | |
| CD1.2 34 |
|
ManyToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany |
- Species where no ortholog for CD1B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for CD1B Gene
- ENSEMBL:
- Gene Tree for CD1B (if available)
- TreeFam:
- Gene Tree for CD1B (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CD1B: view image
Paralogs for CD1B Gene
Variants for CD1B Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000018316 | -- | 158,332,576(-) | T/C | upstream_transcript_variant | |
| rs1000025086 | -- | 158,300,913(-) | C/G | genic_downstream_transcript_variant, intron_variant | |
| rs1000087849 | -- | 158,316,170(-) | A/T | genic_downstream_transcript_variant, intron_variant | |
| rs1000129912 | -- | 158,327,758(-) | C/T | 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant | |
| rs1000198869 | -- | 158,304,716(-) | G/A | genic_downstream_transcript_variant, intron_variant |
Residual Variation Intolerance Score:
80.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.03;
37.34% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CD1B Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CD1B
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CD1B Gene
Disorders for CD1B Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| mycobacterium malmoense |
|
|
| mycobacterium tuberculosis 1 |
|
|
| immune system organ benign neoplasm |
|
|
| thymus lipoma |
|
|
| leprosy 3 |
|
|
Search CD1B in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CD1B
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for CD1B Gene
Publications for CD1B Gene
- Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b. (PMID: 16874306) Garcia-Alles LF … Mourey L (The EMBO journal 2006) 3 4 22 58
- Saposin C is required for lipid presentation by human CD1b. (PMID: 14716313) Winau F … Schaible UE (Nature immunology 2004) 3 4 22 58
- Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens. (PMID: 10899914) Briken V … Porcelli SA (The Journal of experimental medicine 2000) 3 4 22 58
- Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c. (PMID: 2447586) Martin LH … Milstein C (Proceedings of the National Academy of Sciences of the United States of America 1987) 2 3 4 58
- CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice. (PMID: 19808251) Felio K … Wang CR (The Journal of experimental medicine 2009) 3 22 58
Products for CD1B Gene
- R&D Systems Antibodies for CD1B (CD1b)
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CD1B
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CD1B
- antibodies-online: Search results for 207 available CD1b Antibodies ranked by validation data
- Compare Top CD1b Antibodies
- antibodies-online: Search results for 1 available CD1b Elisa Kits ranked by validation data
- Compare Top CD1b Elisa Kits
- Quality Products:
- antibodies-online: Search results for 11 available CD1b Proteins ranked by validation data
- Compare Top CD1b Proteins
- Quality Products:
- GeneTex CD1B Antibody for CD1B
- Search GeneTex for Proteins for CD1B
- Santa Cruz Biotechnology (SCBT) Antibodies for CD1B
- Search Santa Cruz Biotechnology (SCBT) for CD1B siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CD1B
- Horizon Cell Lines for CD1B
- genomics-online: cdna clones - Search results for 55 available CD1b gene related products
- Overview of 55 available CD1b gene related products
- orf clones - Search results for 55 available CD1b gene related products
- Overview of 55 available CD1b gene related products
- genomics-online: gRNA clones - Search results for 55 available CD1b gene related products
- Overview of 55 available CD1b gene related products
- genomics-online: primer clones - Search results for 55 available CD1b gene related products
- Overview of 55 available CD1b gene related products
- genomics-online: shRNA clones - Search results for 55 available CD1b gene related products
- Overview of 55 available CD1b gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CD1B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CD1B
- GeneCopoeia miRNA 3'UTR Target clone products for CD1B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CD1B
Sources for CD1B Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt