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CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recogni... See more...
Aliases for CD180 Gene
Aliases for CD180 Gene
External Ids for CD180 Gene
- HGNC: 6726
- Entrez Gene: 4064
- Ensembl: ENSG00000134061
- OMIM: 602226
- UniProtKB: Q99467
Previous HGNC Symbols for CD180 Gene
- LY64
Previous GeneCards Identifiers for CD180 Gene
- GC05M066514
- GC05M063436
Summaries for CD180 Gene
-
CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008]
GeneCards Summary for CD180 Gene
CD180 (CD180 Molecule) is a Protein Coding gene. Diseases associated with CD180 include Retinitis Pigmentosa 14. Among its related pathways are Activated TLR4 signalling and IL-2 Pathway. An important paralog of this gene is TLR8.
UniProtKB/Swiss-Prot Summary for CD180 Gene
-
May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity).
Additional gene information for CD180 Gene
- HGNC(6726)
- Entrez Gene(4064)
- Ensembl(ENSG00000134061)
- OMIM(602226)
- UniProtKB(Q99467)
- Open Targets Platform(ENSG00000134061)
- Search for CD180 at DataMed
- Search for CD180 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CD180 Gene
Genomics for CD180 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CD180 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CD180 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CD180
- Top Transcription factor binding sites by QIAGEN in the CD180 gene promoter:
-
- COMP1
- FOXJ2
- FOXJ2 (long isoform)
- IRF-1
- LCR-F1
- LUN-1
- Oct-B1
- oct-B2
- POU2F2 (Oct-2.1)
- RORalpha1
Genomic Locations for CD180 Gene
Genomic Locations for CD180 Gene
- chr5:67,179,613-67,196,799
- (GRCh38/hg38)
- Size:
- 17,187 bases
- Orientation:
- Minus strand
- chr5:66,478,103-66,492,627
- (GRCh37/hg19)
- Size:
- 14,525 bases
- Orientation:
- Minus strand
Genomic View for CD180 Gene
Genes around CD180 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q12.3 by HGNC
- 5q12.3 by Entrez Gene
- 5q12.3 by Ensembl
CD180 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CD180 Gene
Proteins for CD180 Gene
-
Protein details for CD180 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q99467-CD180_HUMAN
- Recommended name:
- CD180 antigen
- Protein Accession:
- Q99467
- B2R7Z7
- Q32MM5
Protein attributes for CD180 Gene
- Size:
- 661 amino acids
- Molecular mass:
- 74179 Da
- Quaternary structure:
-
- M-shaped tetramer of two CD180-LY86 heterodimers.
Protein Expression for CD180 Gene
Post-translational modifications for CD180 Gene
Other Protein References for CD180 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ CD180 Antibody
-
Custom Antibody ServicesOriGene Antibodies for CD180
- Novus Biologicals Antibodies for CD180
-
Abcam antibodies for CD180
- Invitrogen Antibodies for CD180 (AFLGC-Cd180)
- antibodies-online: Show 45 available CD180 Antibodies ranked by validation data
- Compare Top CD180 Antibodies
-
Recommended
- 3 WB Antibodies (anti-rat)
- 18 WB Antibodies (anti-mouse)
- 15 FACS Antibodies (anti-mouse)
- 1 IHC (p) Antibody (anti-mouse)
- 1 IP Antibody (anti-mouse)
- 46 WB Antibodies (anti-human)
- 31 FACS Antibodies (anti-human)
- 27 IP Antibodies (anti-human)
- 8 IHC Antibodies (anti-human)
- 3 IHC (p) Antibodies (anti-human)
- 1 IF Antibody (anti-human)
- 1 IHC (fro) Antibody (anti-human)
-
Custom Antibody ServicesProSci Antibodies for CD180
-
Santa Cruz Biotechnology (SCBT) Antibodies for CD180
- Sino Biological Antibodies for CD180
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CD180
- Origene Custom Protein Services for CD180
- Novus Biologicals proteins for CD180
- Sino Biological Cell Lysates for CD180
- Sino Biological Recombinant Proteins for CD180
-
Abcam proteins for CD180
Assay Products
- antibodies-online: Show 3 available CD180 Elisa Kits ranked by validation data
- Compare Top CD180 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for CD180 Gene
Domains & Families for CD180 Gene
Gene Families for CD180 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- CD markers
- Predicted membrane proteins
Protein Domains for CD180 Gene
- InterPro:
- Blocks:
-
- Cysteine-rich flanking region, C-terminal
- ProtoNet:
Suggested Antigen Peptide Sequences for CD180 Gene
- GenScript: Design optimal peptide antigens:
-
- Radioprotective 105 kDa protein (CD180_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q99467- Family:
-
- Belongs to the Toll-like receptor family.
Function for CD180 Gene
Molecular function for CD180 Gene
- UniProtKB/Swiss-Prot Function:
- May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity).
Phenotypes From GWAS Catalog for CD180 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 21857663 |
Phenotypes for CD180 Gene
- MGI mutant phenotypes for CD180:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CD180:
Animal Models for CD180 Gene
- MGI Knock Outs for CD180:
-
- Cd180 Cd180<tm1Kmiy>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CD180 - Select products 50% OFF >
- * CD180 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for CD180
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CD180
-
Santa Cruz Biotechnology (SCBT) CRISPR for CD180
miRNA for CD180 Gene
- miRTarBase miRNAs that target CD180
-
- hsa-miR-4291 (MIRT496004)
- hsa-miR-3622b-5p (MIRT496005)
- hsa-miR-107 (MIRT496006)
- hsa-miR-103a-3p (MIRT496007)
- hsa-miR-5702 (MIRT496008)
- hsa-miR-761 (MIRT496009)
- hsa-miR-3619-5p (MIRT496010)
- hsa-miR-214-3p (MIRT496011)
- hsa-miR-922 (MIRT496012)
- hsa-miR-6838-5p (MIRT496013)
- hsa-miR-497-5p (MIRT496014)
- hsa-miR-424-5p (MIRT496015)
- hsa-miR-195-5p (MIRT496016)
- hsa-miR-16-5p (MIRT496017)
- hsa-miR-15b-5p (MIRT496018)
- hsa-miR-15a-5p (MIRT496019)
- hsa-miR-1277-5p (MIRT519161)
- hsa-miR-190a-3p (MIRT519162)
- hsa-miR-4789-5p (MIRT519163)
- hsa-miR-3941 (MIRT519164)
- hsa-miR-5011-5p (MIRT519165)
- hsa-miR-4789-3p (MIRT519166)
- hsa-miR-603 (MIRT519167)
- hsa-miR-362-3p (MIRT519168)
- hsa-miR-329-3p (MIRT519169)
- hsa-miR-8485 (MIRT519170)
- hsa-miR-5192 (MIRT612094)
- hsa-miR-4644 (MIRT612095)
- hsa-miR-4306 (MIRT612096)
- hsa-miR-185-5p (MIRT612097)
- hsa-miR-6514-5p (MIRT612098)
- hsa-miR-8076 (MIRT612099)
- hsa-miR-4802-5p (MIRT612100)
- hsa-miR-5580-3p (MIRT612101)
- hsa-miR-101-3p (MIRT735792)
- hsa-miR-25-3p (MIRT739351)
- hsa-miR-25-5p (MIRT739374)
- hsa-miR-32-5p (MIRT741245)
- hsa-miR-363-3p (MIRT741796)
- hsa-miR-367-3p (MIRT742112)
- hsa-miR-4325 (MIRT744077)
- hsa-miR-4459 (MIRT744785)
- hsa-miR-582-5p (MIRT751517)
- hsa-miR-6087 (MIRT751902)
- hsa-miR-655-5p (MIRT753474)
- hsa-miR-658 (MIRT753511)
- hsa-miR-6807-5p (MIRT756516)
- hsa-miR-7703 (MIRT759707)
- hsa-miR-92a-3p (MIRT760615)
- hsa-miR-92b-3p (MIRT760643)
- hsa-miR-1288-5p (MIRT762250)
- hsa-miR-149-3p (MIRT762771)
- hsa-miR-30c-1-3p (MIRT764648)
- hsa-miR-30c-2-3p (MIRT764693)
- hsa-miR-3122 (MIRT764799)
- hsa-miR-3190-5p (MIRT765357)
- hsa-miR-3614-5p (MIRT766031)
- hsa-miR-383-3p (MIRT767555)
- hsa-miR-3913-5p (MIRT767603)
- hsa-miR-3926 (MIRT767699)
- hsa-miR-4433a-3p (MIRT768986)
- hsa-miR-450a-1-3p (MIRT769836)
- hsa-miR-4728-5p (MIRT771686)
- hsa-miR-4768-3p (MIRT772064)
- hsa-miR-548s (MIRT774490)
- hsa-miR-6089 (MIRT775730)
- hsa-miR-6500-3p (MIRT776438)
- hsa-miR-6513-5p (MIRT776989)
- hsa-miR-6785-5p (MIRT779096)
- hsa-miR-6788-5p (MIRT779225)
- hsa-miR-6799-5p (MIRT779386)
- hsa-miR-6849-3p (MIRT780257)
- hsa-miR-6883-5p (MIRT780892)
- hsa-miR-7106-5p (MIRT781321)
- hsa-miR-7112-5p (MIRT781452)
- hsa-miR-7977 (MIRT782279)
- hsa-miR-887-5p (MIRT782547)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CD180
- Browse OriGene Inhibitory RNA Products For CD180
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CD180
Clone Products
- Applied Biological Materials (abm): Clones for CD180 - Select products 50% OFF >
- * CD180 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for CD180
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CD180
Cell Line Products
-
Horizon Cell Lines for CD180
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CD180 Gene
Localization for CD180 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CD180 Gene
- Cell membrane. Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 4 |
| nucleus | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| cytosol | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | extracellular space | IBA | 21873635 |
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0031012 | extracellular matrix | IBA | 21873635 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CD180 Gene
Pathways & Interactions for CD180 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Innate Immune System |
.61
|
|
| 2 | Activated TLR4 signalling | ||
| 3 | IL-2 Pathway |
PI3K Signaling in B-Lymphocyte
.35
|
|
| 4 | Toll-like Receptor Signaling Pathway | ||
Pathways by source for CD180 Gene
1 BioSystems pathway for CD180 Gene
4 Reactome pathways for CD180 Gene
1 Qiagen pathway for CD180 Gene
- PI3K Signaling in B-Lymphocyte
Interacting Proteins for CD180 Gene
Selected Interacting proteins:
Q99467-CD180_HUMAN
ENSP00000256447
for CD180 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for CD180
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002322 | B cell proliferation involved in immune response | IEA,IBA | 21873635 |
| GO:0002376 | immune system process | IEA | -- |
| GO:0006954 | inflammatory response | IEA | -- |
| GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway | IBA,IGI | 10880523 |
| GO:0045087 | innate immune response | IEA | -- |
No data available for SIGNOR curated interactions for CD180 Gene
Transcripts for CD180 Gene
mRNA/cDNA for CD180 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000256447 5388 nts (view in UCSC)
- ENST00000515027 511 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CD180 - Select products 50% OFF >
- * CD180 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for CD180
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CD180
-
Santa Cruz Biotechnology (SCBT) CRISPR for CD180
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CD180
- Browse OriGene Inhibitory RNA Products For CD180
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CD180
Clone Products
- Applied Biological Materials (abm): Clones for CD180 - Select products 50% OFF >
- * CD180 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for CD180
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CD180
Relevant External Links for CD180 Gene
- GeneLoc Exon Structure for
- CD180
Expression for CD180 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for CD180 Gene
This gene is overexpressed in Spleen (x11.4) and Whole Blood (x7.0).
This gene is overexpressed in Blymphocyte (24.0), Monocytes (19.8), and Lymph node (15.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CD180 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CD180
SOURCE GeneReport for Unigene cluster for CD180 Gene:
Hs.87205mRNA Expression by UniProt/SwissProt for CD180 Gene:
Q99467-CD180_HUMAN
Tissue specificity:
Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
Evidence on tissue expression from TISSUES for CD180 Gene
- Lung(4.3)
- Liver(4.3)
- Spleen(3)
- Lymph node(2.8)
- Blood(2.7)
- Bone marrow(2.5)
- Intestine(2)
Primer Products
-
OriGene qPCR primer pairs for CD180
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CD180 Gene
Orthologs for CD180 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | CD180 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | CD180 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | CD180 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Cd180 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Cd180 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | CD180 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | CD180 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | CD180 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | CD180 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | cd180 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | LOC101885327 30 |
|
||
| CD180 (2 of 2) 31 |
|
OneToMany | |||
| cd180 31 |
|
OneToMany |
- Species where no ortholog for CD180 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for CD180 Gene
- ENSEMBL:
- Gene Tree for CD180 (if available)
- TreeFam:
- Gene Tree for CD180 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CD180: view image
Paralogs for CD180 Gene
Variants for CD180 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CD180 Gene
| SNP ID | Clinical significance and condition | Chr 05 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 709971 | Benign: not provided | 67,183,091(-) | C/T | SYNONYMOUS_VARIANT | |
| 725876 | Likely Benign: not provided | 67,183,037(-) | C/T | SYNONYMOUS_VARIANT | |
| 725877 | Benign: not provided | 67,184,177(-) | C/T | SYNONYMOUS_VARIANT | |
| 757510 | Likely Benign: not provided | 67,184,177(-) | C/G | SYNONYMOUS_VARIANT | |
| 782700 | Benign: not provided | 67,183,649(-) | C/T | SYNONYMOUS_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2759347 | CNV | gain | 17122850 |
Residual Variation Intolerance Score:
71.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.03;
75.07% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CD180 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CD180
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CD180 Gene
Disorders for CD180 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| retinitis pigmentosa 14 |
|
|
Search CD180 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CD180
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for CD180 Gene
Publications for CD180 Gene
- RP105 is associated with MD-1 and transmits an activation signal in human B cells. (PMID: 9763566) Miura Y … Kimoto M (Blood 1998) 2 3 4 23
- Molecular cloning of a human RP105 homologue and chromosomal localization of the mouse and human RP105 genes (Ly64 and LY64). (PMID: 8975706) Miura Y … Kimoto M (Genomics 1996) 2 3 4 23
- A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. (PMID: 22219177) Tao S … Sun J (Carcinogenesis 2012) 3 41
- Crystal structures of mouse and human RP105/MD-1 complexes reveal unique dimer organization of the toll-like receptor family. (PMID: 21959264) Ohto U … Shimizu T (Journal of molecular biology 2011) 3 4
- Potentiation of TLR9 responses for human naïve B-cell growth through RP105 signaling. (PMID: 20133206) Yamazaki K … Agematsu K (Clinical immunology (Orlando, Fla.) 2010) 3 23
ExternalLinks
Products for CD180 Gene
- Custom Antibody ServicesOriGene Antibodies for CD180
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CD180
- Origene Custom Protein Services for CD180
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CD180
- Browse OriGene Inhibitory RNA Products For CD180
- OriGene qPCR primer pairs for CD180
- OriGene CRISPR knockouts for CD180
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CD180
- Sino Biological Human cDNA Clone for CD180
- Sino Biological Cell Lysates for CD180
- Sino Biological Recombinant Proteins for CD180
- Sino Biological Antibodies for CD180
- Browse Sino Biological Assays
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- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for CD180
- Novus Biologicals proteins for CD180
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for CD180
- Abcam proteins for CD180
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
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- Browse Matched Antibody Pairs
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- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for CD180 (AFLGC-Cd180)
- VectorBuilder Custom and pre-made DNA vectors for CD180 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for CD180 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for CD180 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for CD180 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for CD180
- antibodies-online: Show 45 available CD180 Antibodies ranked by validation data
- Compare Top CD180 Antibodies
- Recommended
- 3 WB Antibodies (anti-rat)
- 18 WB Antibodies (anti-mouse)
- 15 FACS Antibodies (anti-mouse)
- 1 IHC (p) Antibody (anti-mouse)
- 1 IP Antibody (anti-mouse)
- 46 WB Antibodies (anti-human)
- 31 FACS Antibodies (anti-human)
- 27 IP Antibodies (anti-human)
- 8 IHC Antibodies (anti-human)
- 3 IHC (p) Antibodies (anti-human)
- 1 IF Antibody (anti-human)
- 1 IHC (fro) Antibody (anti-human)
- antibodies-online: Show 3 available CD180 Elisa Kits ranked by validation data
- Compare Top CD180 Elisa Kits
- Quality Products:
- antibodies-online: Show 7 available CD180 Proteins ranked by validation data
- Compare Top CD180 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for CD180
- Search Santa Cruz Biotechnology (SCBT) for CD180 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CD180
- Custom Antibody ServicesProSci Antibodies for CD180
- Search for CD180 Proteins at ProSci
- Horizon Cell Lines for CD180
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CD180
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CD180
- Search GeneCopoeia for miRNA 3'UTR Target clone products for CD180
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CD180
Sources for CD180 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB