Aliases for CD151 Gene
External Ids for CD151 Gene
Previous GeneCards Identifiers for CD151 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for CD151 Gene
CD151 (CD151 Molecule (Raph Blood Group)) is a Protein Coding gene. Diseases associated with CD151 include Nephropathy With Pretibial Epidermolysis Bullosa And Deafness and Raph Blood Group System. Among its related pathways are Cell junction organization and Degradation of the extracellular matrix. Gene Ontology (GO) annotations related to this gene include integrin binding. An important paralog of this gene is TSPAN11.