Aliases for CCT7 Gene
External Ids for CCT7 Gene
Previous GeneCards Identifiers for CCT7 Gene
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6. [provided by RefSeq, Oct 2009]
GeneCards Summary for CCT7 Gene
CCT7 (Chaperonin Containing TCP1 Subunit 7) is a Protein Coding gene. Diseases associated with CCT7 include Myocardial Infarction and Babesiosis. Among its related pathways are Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding and Cell cycle_Role of APC in cell cycle regulation. Gene Ontology (GO) annotations related to this gene include identical protein binding and unfolded protein binding.
UniProtKB/Swiss-Prot for CCT7 Gene
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).