Aliases for CCNYL2 Gene

Aliases for CCNYL2 Gene

  • Cyclin Y Like 2 (Pseudogene) 2 3 5
  • Cyclin-Y-Like Protein 2 3 4
  • BA178A10.2 2 3
  • C10orf21 3 4
  • CCNYL2P 2 3
  • Chromosome 10 Open Reading Frame 21 2
  • Cyclin Y-Like 2 2
  • CCNYL2 5

External Ids for CCNYL2 Gene

Previous HGNC Symbols for CCNYL2 Gene

  • C10orf21

Previous GeneCards Identifiers for CCNYL2 Gene

  • GC10M042225
  • GC10M042903
  • GC10M039430
  • GC10M042418
  • GC10M042421
  • GC10M042446
  • GC10M042449
  • GC10M042452
  • GC10M042463
  • GC10M042423
  • GC10M042426
  • GC10M042429
  • GC10M042431
  • GC10M042434
  • GC10M042437
  • GC10M042440
  • GC10M042443

Summaries for CCNYL2 Gene

GeneCards Summary for CCNYL2 Gene

CCNYL2 (Cyclin Y Like 2 (Pseudogene)) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include protein kinase binding.

Additional gene information for CCNYL2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CCNYL2 Gene

Genomics for CCNYL2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CCNYL2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J042474 Promoter/Enhancer 1.3 EPDnew Ensembl ENCODE 250.7 -0.9 -938 2.6 ZIC2 SP2 CTCF GLIS1 L3MBTL2 RCOR1 ZFX POLR2A ZNF692 PATZ1 LINC00839 CCNYL2 lnc-ZNF33B-6 ZNF33B LOC441666 piR-54183
GH10J043042 Enhancer 0.7 Ensembl CraniofacialAtlas 5 -568.6 -568649 2.9 ZIC2 MYC FOXA1 MAX REST CTCF GLIS1 RAD21 ZFX EP300 LINC00839 CCNYL2 ENSG00000259869 ZNF33B HSALNG0077522 LINC01264 piR-32214-054 RET BMS1
GH10J042826 Enhancer 0.6 Ensembl ENCODE 3.9 -352.1 -352088 1.5 CTCF KLF1 RAD21 HE856085 piR-49555-001 LOC441666 CCNYL2 BMS1 RET
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CCNYL2 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the CCNYL2 gene promoter:
  • AML1a
  • AREB6
  • E47
  • FOXC1
  • p53
  • Pax-4a
  • Tal-1beta
  • USF-1:USF-2
  • USF1
  • USF2

Genomic Locations for CCNYL2 Gene

Latest Assembly
67,182 bases
Minus strand

Previous Assembly
(GRCh37/hg19 by Entrez Gene)
64,067 bases
Minus strand

(GRCh37/hg19 by Ensembl)
64,073 bases
Minus strand

Genomic View for CCNYL2 Gene

Genes around CCNYL2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCNYL2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCNYL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCNYL2 Gene

Proteins for CCNYL2 Gene

  • Protein details for CCNYL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Cyclin-Y-like protein 2
    Protein Accession:

    Protein attributes for CCNYL2 Gene

    361 amino acids
    Molecular mass:
    41278 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCNYL2 Gene

Post-translational modifications for CCNYL2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCNYL2 Gene

Domains & Families for CCNYL2 Gene

Gene Families for CCNYL2 Gene


Protein Domains for CCNYL2 Gene

Suggested Antigen Peptide Sequences for CCNYL2 Gene

GenScript: Design optimal peptide antigens:
  • Cyclin-Y-like protein 2 (CCYL2_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the cyclin family. Cyclin Y subfamily.
  • Belongs to the cyclin family. Cyclin Y subfamily.
genes like me logo Genes that share domains with CCNYL2: view

Function for CCNYL2 Gene

Phenotypes From GWAS Catalog for CCNYL2 Gene

Gene Ontology (GO) - Molecular Function for CCNYL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IBA 21873635
GO:0019901 protein kinase binding IEA --
genes like me logo Genes that share ontologies with CCNYL2: view
genes like me logo Genes that share phenotypes with CCNYL2: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCNYL2 Gene

Localization for CCNYL2 Gene

Gene Ontology (GO) - Cellular Components for CCNYL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA 21873635
GO:0005886 plasma membrane IBA 21873635
genes like me logo Genes that share ontologies with CCNYL2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for CCNYL2 Gene

Pathways & Interactions for CCNYL2 Gene

PathCards logo

SuperPathways for CCNYL2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCNYL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IBA 21873635
genes like me logo Genes that share ontologies with CCNYL2: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for CCNYL2 Gene

Drugs & Compounds for CCNYL2 Gene

No Compound Related Data Available

Transcripts for CCNYL2 Gene

mRNA/cDNA for CCNYL2 Gene

1 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CCNYL2 Gene

No ASD Table

Relevant External Links for CCNYL2 Gene

GeneLoc Exon Structure for

Expression for CCNYL2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CCNYL2 Gene

mRNA differential expression in normal tissues according to GTEx for CCNYL2 Gene

This gene is overexpressed in Testis (x25.8).

Protein differential expression in normal tissues from HIPED for CCNYL2 Gene

This gene is overexpressed in Pancreas (51.3) and Brain (17.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCNYL2 Gene

Protein tissue co-expression partners for CCNYL2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CCNYL2

genes like me logo Genes that share expression patterns with CCNYL2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCNYL2 Gene

Orthologs for CCNYL2 Gene

Evolution for CCNYL2 Gene

Gene Tree for CCNYL2 (if available)
Gene Tree for CCNYL2 (if available)

No data available for Orthologs for CCNYL2 Gene

Paralogs for CCNYL2 Gene

(8) SIMAP similar genes for CCNYL2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CCNYL2: view

No data available for Paralogs for CCNYL2 Gene

Variants for CCNYL2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CCNYL2 Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
rs2489720 - p.Arg176Gln
rs2490085 - p.Val57Glu
rs2505861 - p.Ile288Val

Structural Variations from Database of Genomic Variants (DGV) for CCNYL2 Gene

Variant ID Type Subtype PubMed ID
dgv1097n54 CNV gain 21841781
dgv1098n54 CNV gain 21841781
dgv1102n54 CNV gain 21841781
dgv1103n54 CNV gain 21841781
dgv113e214 CNV gain 21293372
dgv719n100 CNV gain 25217958
dgv78n27 CNV gain 19166990
dgv79n27 CNV gain 19166990
esv2328272 CNV deletion 18987734
esv2759746 CNV loss 17122850
esv3428772 CNV duplication 20981092
esv3576449 CNV gain 25503493
esv3623002 CNV gain 21293372
esv3623007 CNV loss 21293372
esv3623008 CNV gain 21293372
esv3623011 CNV loss 21293372
esv3891789 CNV gain 25118596
esv3891790 CNV gain 25118596
esv3891791 CNV gain 25118596
esv3891795 CNV gain 25118596
nsv1042764 CNV gain 25217958
nsv1051346 CNV gain 25217958
nsv1119805 CNV deletion 24896259
nsv433411 CNV gain 18776910
nsv466877 CNV gain 19166990
nsv469725 CNV gain 16826518
nsv470932 CNV gain 18288195
nsv471665 CNV gain 15918152
nsv550672 CNV gain 21841781
nsv550680 CNV loss 21841781
nsv825348 CNV loss 20364138
nsv947880 CNV duplication 23825009
nsv947881 CNV duplication 23825009

Additional Variant Information for CCNYL2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance and Variation tolerance for CCNYL2 Gene

Disorders for CCNYL2 Gene

Additional Disease Information for CCNYL2

No disorders were found for CCNYL2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCNYL2 Gene

Publications for CCNYL2 Gene

  1. Cellular redox sensor HSCARG negatively regulates the translesion synthesis pathway and exacerbates mammary tumorigenesis. (PMID: 31796584) Zang W … Zheng X (Proceedings of the National Academy of Sciences of the United States of America 2019) 3
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  3. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for CCNYL2 Gene

Sources for CCNYL2 Gene