The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cycli... See more...

Aliases for CCND3 Gene

Aliases for CCND3 Gene

  • Cyclin D3 2 3 5
  • G1/S-Specific Cyclin-D3 3 4
  • D3-Type Cyclin 3
  • CCND3 5

External Ids for CCND3 Gene

Previous GeneCards Identifiers for CCND3 Gene

  • GC06M041904
  • GC06M041949
  • GC06M042010
  • GC06M041621

Summaries for CCND3 Gene

Entrez Gene Summary for CCND3 Gene

  • The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

CIViC Summary for CCND3 Gene

  • Cyclin D has been shown in many cancer types to be misregulated. Well established for their oncogenic properties, the cyclins and the cyclin-dependent kinases (CDK's) they activate have been the focus of major research and development efforts over the past decade. The methods by which the cyclins are misregulated are widely variable, ranging from genomic amplification to changes in promoter methylation. Cyclin D3 loss has been reported in T-ALL, a seemingly unique trend when compared to the amplifcations and overexpressions of the other cyclin D's. In a mouse study, the targeted therapeutic palbociclib significantly increased the median survival of the cyclin D3 knockouts.

GeneCards Summary for CCND3 Gene

CCND3 (Cyclin D3) is a Protein Coding gene. Diseases associated with CCND3 include Bladder Carcinoma In Situ and Retinoblastoma. Among its related pathways are E2F transcription factor network and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include protein kinase binding and cyclin-dependent protein serine/threonine kinase activity. An important paralog of this gene is CCND2.

UniProtKB/Swiss-Prot Summary for CCND3 Gene

  • Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

Gene Wiki entry for CCND3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CCND3 Gene

Genomics for CCND3 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CCND3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CCND3 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CCND3

Top Transcription factor binding sites by QIAGEN in the CCND3 gene promoter:
  • AML1a

Genomic Locations for CCND3 Gene

Genomic Locations for CCND3 Gene
chr6:41,934,933-42,050,357
(GRCh38/hg38)
Size:
115,425 bases
Orientation:
Minus strand
chr6:41,902,671-42,018,095
(GRCh37/hg19)
Size:
115,425 bases
Orientation:
Minus strand

Genomic View for CCND3 Gene

Genes around CCND3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCND3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCND3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCND3 Gene

Proteins for CCND3 Gene

  • Protein details for CCND3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P30281-CCND3_HUMAN
    Recommended name:
    G1/S-specific cyclin-D3
    Protein Accession:
    P30281
    Secondary Accessions:
    • B2RD63
    • B3KQ22
    • E9PAS4
    • E9PB36
    • Q5T8J0
    • Q6FG62
    • Q96F49

    Protein attributes for CCND3 Gene

    Size:
    292 amino acids
    Molecular mass:
    32520 Da
    Quaternary structure:
    • Interacts with the CDK4 and CDK6 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. Interacts with ATF5. Interacts with EIF3K. Component of the ternary complex cyclin D/CDK4/CDKN1B required for nuclear translocation and modulation of CDK4-mediated kinase activity. Can form similar complexes with either CDKN1A or CDKN2A.

    Three dimensional structures from OCA and Proteopedia for CCND3 Gene

    Alternative splice isoforms for CCND3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCND3 Gene

Post-translational modifications for CCND3 Gene

  • Polyubiquitinated by the SCF(FBXL2) complex, leading to proteasomal degradation.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for CCND3 Gene

Domains & Families for CCND3 Gene

Gene Families for CCND3 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Predicted intracellular proteins

Protein Domains for CCND3 Gene

Suggested Antigen Peptide Sequences for CCND3 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ32644 fis, clone SYNOV2001239, highly similar to G1/S-specific cyclin-D3 (B3KQ22_HUMAN)
  • cDNA FLJ38957 fis, clone NT2RI2000128, highly similar to G1/S-specific cyclin-D3 (B3KTY3_HUMAN)
  • G1/S-specific cyclin-D3 (CCND3_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P30281

UniProtKB/Swiss-Prot:

CCND3_HUMAN :
  • Belongs to the cyclin family. Cyclin D subfamily.
Family:
  • Belongs to the cyclin family. Cyclin D subfamily.
genes like me logo Genes that share domains with CCND3: view

Function for CCND3 Gene

Molecular function for CCND3 Gene

UniProtKB/Swiss-Prot Function:
Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
GENATLAS Biochemistry:
cyclin D3,regulator of progression through G1 phase during the cell cycle 3,33/34kDa,overexpressed with CDKN1B in agressive B cell lymphomas and in glioblastoma and gliosarcoma,involved in the loss of cell cycle control in a small fraction of malignant gliomas

Phenotypes From GWAS Catalog for CCND3 Gene

Gene Ontology (GO) - Molecular Function for CCND3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity IBA --
GO:0004693 cyclin-dependent protein serine/threonine kinase activity IEA --
GO:0005515 protein binding IPI 9106657
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IBA 21873635
GO:0019901 protein kinase binding IPI 8114739
genes like me logo Genes that share ontologies with CCND3: view
genes like me logo Genes that share phenotypes with CCND3: view

Animal Models for CCND3 Gene

MGI Knock Outs for CCND3:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CCND3

Clone Products

  • Addgene plasmids for CCND3

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CCND3 Gene

Localization for CCND3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCND3 Gene

Nucleus. Cytoplasm. Membrane. Note=Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated to the nucleus through interaction with KIP/CIP family members. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCND3 gene
Compartment Confidence
nucleus 5
cytosol 5
plasma membrane 3
extracellular 2
cytoskeleton 2
mitochondrion 2
endoplasmic reticulum 2
peroxisome 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nuclear bodies (3)
  • Nucleoplasm (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CCND3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000307 cyclin-dependent protein kinase holoenzyme complex IDA 8114739
GO:0005634 nucleus IBA 21873635
GO:0005654 nucleoplasm TAS --
GO:0005737 cytoplasm IBA 21873635
GO:0005829 cytosol IDA --
genes like me logo Genes that share ontologies with CCND3: view

Pathways & Interactions for CCND3 Gene

PathCards logo

SuperPathways for CCND3 Gene

genes like me logo Genes that share pathways with CCND3: view

Pathways by source for CCND3 Gene

9 GeneGo (Thomson Reuters) pathways for CCND3 Gene
  • Cell cycle Cell cycle (generic schema)
  • Cell cycle Regulation of G1/S transition (part 1)
  • Cell cycle Regulation of G1/S transition (part 2)
  • Cytoskeleton remodeling FAK signaling
  • Development IGF-1 receptor signaling
1 R&D Systems pathway for CCND3 Gene
9 Qiagen pathways for CCND3 Gene
  • Akt Signaling
  • Breast Cancer Regulation by Stathmin1
  • Calpain Protease Regulates Cellular Mechanics
  • Cyclins and Cell Cycle Regulation
  • G1-S Phase Transition
1 Cell Signaling Technology pathway for CCND3 Gene
1 GeneTex pathway for CCND3 Gene

SIGNOR curated interactions for CCND3 Gene

Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for CCND3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity IBA 21873635
GO:0000122 negative regulation of transcription by RNA polymerase II IEA --
GO:0001934 positive regulation of protein phosphorylation IDA 8114739
GO:0006468 protein phosphorylation IEA --
GO:0007049 cell cycle IEA --
genes like me logo Genes that share ontologies with CCND3: view

Drugs & Compounds for CCND3 Gene

(30) Drugs for CCND3 Gene - From: DGIdb and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
BAY1000394 Pharma Inhibition, Biomarker CDK4 Inhibitors, CDK2 Inhibitors 0
LEE011 Pharma inhibitor, Biomarker CDK4/6 inhibitor, CDK4 Inhibitors, Kinase Inhibitors 0
LY2835219 Pharma Inhibition, inhibitor, Biomarker CDK4/6 inhibitor,potent and selective, CDK4/6 inhibitor, CDK4 Inhibitors 0
PD 0332991 Pharma Biomarker CDK4 Inhibitors 0

(12) Additional Compounds for CCND3 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with CCND3: view

Transcripts for CCND3 Gene

mRNA/cDNA for CCND3 Gene

6 REFSEQ mRNAs :
26 NCBI additional mRNA sequence :
23 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CCND3

Clone Products

  • Addgene plasmids for CCND3

Alternative Splicing Database (ASD) splice patterns (SP) for CCND3 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c · 8d
SP1: - - - -
SP2: - - -
SP3: - - - - -
SP4: - -
SP5: - - - - -
SP6: -
SP7: -

Relevant External Links for CCND3 Gene

GeneLoc Exon Structure for
CCND3

Expression for CCND3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CCND3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCND3 Gene

This gene is overexpressed in Whole Blood (x10.8).

Protein differential expression in normal tissues from HIPED for CCND3 Gene

This gene is overexpressed in Pancreatic juice (53.7) and Peripheral blood mononuclear cells (15.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CCND3 Gene



Protein tissue co-expression partners for CCND3 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CCND3

SOURCE GeneReport for Unigene cluster for CCND3 Gene:

Hs.534307

Evidence on tissue expression from TISSUES for CCND3 Gene

  • Blood(4.8)
  • Lung(4.7)
  • Nervous system(4.6)
  • Spleen(3.4)
  • Bone marrow(3.3)
  • Intestine(3.2)
  • Lymph node(3.2)
  • Pancreas(3.2)
  • Muscle(2.8)
  • Skin(2.7)
  • Liver(2.6)
  • Kidney(2.6)
  • Heart(2.6)
  • Thyroid gland(2.6)
  • Eye(2.6)
  • Stomach(2.5)
  • Adrenal gland(2.3)
genes like me logo Genes that share expression patterns with CCND3: view

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCND3 Gene

Orthologs for CCND3 Gene

This gene was present in the common ancestor of animals.

Orthologs for CCND3 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia CCND3 30 31
  • 99.66 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia CCND3 30 31
  • 93.84 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia CCND3 30 31
  • 93.72 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Ccnd3 30 17 31
  • 90.41 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Ccnd3 30
  • 90.07 (n)
Oppossum
(Monodelphis domestica)
Mammalia CCND3 31
  • 84 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia CCND3 31
  • 80 (a)
OneToOne
Chicken
(Gallus gallus)
Aves CCND3 30 31
  • 73.68 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia CCND3 31
  • 71 (a)
OneToOne
Zebrafish
(Danio rerio)
Actinopterygii ccnd2b 31
  • 50 (a)
ManyToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012299 30
  • 52.7 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta CycD 31 32
  • 24 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 55 (a)
OneToMany
Species where no ortholog for CCND3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for CCND3 Gene

ENSEMBL:
Gene Tree for CCND3 (if available)
TreeFam:
Gene Tree for CCND3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CCND3: view image

Paralogs for CCND3 Gene

(4) SIMAP similar genes for CCND3 Gene using alignment to 8 proteins:

  • CCND3_HUMAN
  • B3KTY3_HUMAN
  • D6RDF8_HUMAN
  • D6RDL3_HUMAN
  • D6RI00_HUMAN
  • D6RIX2_HUMAN
  • H0Y8M4_HUMAN
  • Q5T8J1_HUMAN

Pseudogenes.org Pseudogenes for CCND3 Gene

genes like me logo Genes that share paralogs with CCND3: view

Variants for CCND3 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CCND3 Gene

SNP ID Clinical significance and condition Chr 06 pos Variation AA Info Type
711316 Benign: not provided 41,936,586(-) C/G SYNONYMOUS_VARIANT
719035 Benign: not provided 41,940,535(-) G/A SYNONYMOUS_VARIANT,INTRON_VARIANT
rs1051130 - p.Ser259Ala
rs3218089 - p.Pro134Ser
rs33966734 - p.Glu253Asp

Additional dbSNP identifiers (rs#s) for CCND3 Gene

Structural Variations from Database of Genomic Variants (DGV) for CCND3 Gene

Variant ID Type Subtype PubMed ID
dgv3305n106 CNV deletion 24896259
dgv3306n106 CNV deletion 24896259
esv1427717 CNV deletion 17803354
esv2301238 CNV deletion 18987734
esv2544548 CNV deletion 19546169
esv2659555 CNV deletion 23128226
esv2676088 CNV deletion 23128226
esv2731981 CNV deletion 23290073
esv2731982 CNV deletion 23290073
esv3567701 CNV deletion 23714750
esv3567702 CNV deletion 23714750
esv3567704 CNV deletion 23714750
esv3576144 CNV gain 25503493
esv3608793 CNV loss 21293372
esv3608794 CNV loss 21293372
nsv1074394 CNV deletion 25765185
nsv1114801 CNV deletion 24896259
nsv1117617 CNV deletion 24896259
nsv1124054 CNV deletion 24896259
nsv1137075 CNV deletion 24896259
nsv1142638 CNV deletion 24896259
nsv526116 CNV loss 19592680
nsv527131 CNV loss 19592680
nsv602989 CNV loss 21841781
nsv830646 CNV loss 17160897
nsv830649 CNV loss 17160897
nsv956532 CNV deletion 24416366

Variation tolerance for CCND3 Gene

Residual Variation Intolerance Score: 60% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.31; 41.28% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CCND3 Gene

Human Gene Mutation Database (HGMD)
CCND3
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCND3

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCND3 Gene

Disorders for CCND3 Gene

MalaCards: The human disease database

(29) MalaCards diseases for CCND3 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
bladder carcinoma in situ
  • bladder ca in situ
retinoblastoma
  • rb1
t-cell lymphoblastic leukemia/lymphoma
  • t-cell leukemia
splenic diffuse red pulp small b-cell lymphoma
  • sdrpl
gliosarcoma
  • glioblastoma with sarcomatous component
- elite association - COSMIC cancer census association via MalaCards
Search CCND3 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for CCND3

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
Tumor Gene Database
(TGDB)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with CCND3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CCND3 Gene

Publications for CCND3 Gene

  1. Genomic organization, chromosomal localization, and independent expression of human cyclin D genes. (PMID: 1386335) Inaba T … Look AT (Genomics 1992) 2 3 4 23
  2. The structure of CDK4/cyclin D3 has implications for models of CDK activation. (PMID: 19237555) Takaki T … Noble ME (Proceedings of the National Academy of Sciences of the United States of America 2009) 3 4 23
  3. Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk. (PMID: 19258477) Goode EL … Sellers TA (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009) 3 23 41
  4. Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis. (PMID: 19738611) Cunningham JM … Goode EL (British journal of cancer 2009) 3 23 41
  5. Polymorphic loci of E2F2, CCND1 and CCND3 are associated with HER2 status of breast tumors. (PMID: 19142864) Justenhoven C … Brauch H (International journal of cancer 2009) 3 23 41

Products for CCND3 Gene

  • Addgene plasmids for CCND3

Sources for CCND3 Gene